{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Drugs%2C+Non-Prescription",
    "query": {
      "condition": "Drugs, Non-Prescription"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 97,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Drugs%2C+Non-Prescription&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T10:57:07.457Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04452344",
      "title": "Opioid Analgesic Reduction Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "opioid-containing analgesic",
          "type": "DRUG"
        },
        {
          "name": "two over-the-counter analgesics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1815,
      "start_date": "2021-01-04",
      "completion_date": "2026-07-31",
      "has_results": true,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 5,
      "location_summary": "Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Newark",
          "state": "New Jersey"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04452344"
    },
    {
      "nct_id": "NCT04134767",
      "title": "Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use",
        "HIV Infections",
        "HCV Infection",
        "Sexually Transmitted Infections (Not HIV or Hepatitis)",
        "Overdose, Drug",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Health Linkage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Overdose Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "April M Young",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 234,
      "start_date": "2019-11-15",
      "completion_date": "2022-10-27",
      "has_results": true,
      "last_update_posted_date": "2023-12-21",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04134767"
    },
    {
      "nct_id": "NCT01174706",
      "title": "Impact of Information Prescriptions on Medication Adherence in Emergency Department (ED) Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patient Compliance",
        "Medication Adherence",
        "Medication Non-Adherence"
      ],
      "interventions": [
        {
          "name": "Information prescriptions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3940,
      "start_date": "2010-11",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2018-08-21",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Columbia, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Columbia",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01174706"
    },
    {
      "nct_id": "NCT00681265",
      "title": "Tear Film Break-up Time After Instillation of Artificial Tears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keratoconjunctivitis Sicca"
      ],
      "interventions": [
        {
          "name": "glycerin",
          "type": "DRUG"
        },
        {
          "name": "polyethylene glycol 400/propylene glycol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Calm Water Therapeutics LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2008-06",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2012-10-26",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00681265"
    },
    {
      "nct_id": "NCT04315961",
      "title": "Effects of Dietary Conditions on Drug Response",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Blinded drug dose conditions",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 1,
      "start_date": "2020-09-18",
      "completion_date": "2023-02-02",
      "has_results": true,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04315961"
    },
    {
      "nct_id": "NCT06948513",
      "title": "Effect of Over-the-counter Analgesics on Postoperative Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain Management"
      ],
      "interventions": [
        {
          "name": "Naproxen",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen (Standard of Care)",
          "type": "DRUG"
        },
        {
          "name": "ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Zitelli & Brodland Skin Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 200,
      "start_date": "2022-12-22",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Clairton, Pennsylvania",
      "locations": [
        {
          "city": "Clairton",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06948513"
    },
    {
      "nct_id": "NCT04069403",
      "title": "An Opioid Prescribing Nudge",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use, Unspecified",
        "Prescription Drug Abuse (Not Dependent)",
        "Prescription Drug Abuse and Dependency",
        "Health Behavior",
        "Benzodiazepine Abuse",
        "Benzodiazepine Dependent"
      ],
      "interventions": [
        {
          "name": "Automated Reports on prescription patterns for their patients",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 427,
      "start_date": "2019-09-10",
      "completion_date": "2020-06-15",
      "has_results": false,
      "last_update_posted_date": "2020-06-30",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04069403"
    },
    {
      "nct_id": "NCT00610480",
      "title": "Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "1st visit Optive, then 2nd visit Systane",
          "type": "DRUG"
        },
        {
          "name": "1st visit Systane, then 2nd visit Optive",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2007-11",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00610480"
    },
    {
      "nct_id": "NCT02749123",
      "title": "Comparison of Prescription Lidocaine Patch to Over the Counter Lidocaine Patch and Placebo for Back Pain and Arthritis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Back Pain",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "lidocaine 5% patch",
          "type": "DRUG"
        },
        {
          "name": "lidocaine 3.6%, menthol 1.25%",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "J.A.R. Laboratories",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2016-04",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-04-22",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "Barrington, Illinois",
      "locations": [
        {
          "city": "Barrington",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02749123"
    },
    {
      "nct_id": "NCT03165175",
      "title": "Mobile Application for Prescription Drug-Abuse Education (MAPDE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prescription Drug Abuse (Not Dependent)"
      ],
      "interventions": [
        {
          "name": "prescription drug-abuse education smartphone application",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Naval Health Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 80,
      "start_date": "2017-05-22",
      "completion_date": "2018-10-17",
      "has_results": true,
      "last_update_posted_date": "2019-08-05",
      "last_synced_at": "2026-07-22T10:57:07.457Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03165175"
    }
  ]
}