{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=E+Cig+Use&page=3",
    "query": {
      "condition": "E Cig Use",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 373,
    "total_pages": 38,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=E+Cig+Use&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=E+Cig+Use&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T08:59:47.695Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06077240",
      "title": "Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Smoking Behaviors",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette with 2.4% Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette with 5% Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 3mg Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 6mg Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 6mg Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 256,
      "start_date": "2024-08-20",
      "completion_date": "2028-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06077240"
    },
    {
      "nct_id": "NCT03491059",
      "title": "Feasibility of PET/CT to Detect the Oral/Pulmonary Distribution of Nicotine Following E-cigarette Use",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "E-cigarette Use"
      ],
      "interventions": [
        {
          "name": "C-11 labeled nicotine",
          "type": "DRUG"
        },
        {
          "name": "PET/CT imaging",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "DRUG",
        "RADIATION"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 2,
      "start_date": "2018-02-16",
      "completion_date": "2025-02-16",
      "has_results": false,
      "last_update_posted_date": "2024-01-18",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03491059"
    },
    {
      "nct_id": "NCT06965296",
      "title": "AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence, Cigarettes"
      ],
      "interventions": [
        {
          "name": "AI-enhanced smartphone app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "AI-enhanced smartphone app, but with delayed access",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "14 Years to 20 Years"
      },
      "enrollment_count": 100,
      "start_date": "2026-08-24",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-06",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06965296"
    },
    {
      "nct_id": "NCT04107779",
      "title": "Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "Cigarette Use, Electronic",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch to Dual-use of JUUL 5% and UB of Combustible Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Tobacco/Nicotine Abstention",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand of cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 279,
      "start_date": "2019-09-17",
      "completion_date": "2020-06-24",
      "has_results": false,
      "last_update_posted_date": "2020-07-28",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 5,
      "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Rogers",
          "state": "Arkansas"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04107779"
    },
    {
      "nct_id": "NCT07934875",
      "title": "Understanding Vape Counter-Marketing Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-Cigarette Use",
        "E-cigarette Use/Vaping Prevention",
        "Vaping Teens",
        "Vaping",
        "Adolescent Behavior",
        "Nicotine",
        "Tobacco"
      ],
      "interventions": [
        {
          "name": "Influencer Intervention Videos",
          "type": "OTHER"
        },
        {
          "name": "Public Domain Messaging Videos",
          "type": "OTHER"
        },
        {
          "name": "Influencer Control Videos",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "13 Years to 21 Years"
      },
      "enrollment_count": 2556,
      "start_date": "2026-11-15",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-11-13",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07934875"
    },
    {
      "nct_id": "NCT04450537",
      "title": "PACE Vape Messaging Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vaping",
        "E-cigarette Use",
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Vape Messaging Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 569,
      "start_date": "2020-06-23",
      "completion_date": "2020-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-11-03",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04450537"
    },
    {
      "nct_id": "NCT06868368",
      "title": "Perceptions of Vaping Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abuse Tobacco",
        "Exposure"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "OTHER"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        },
        {
          "name": "Vaping Topography",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Participant's Own Preferred E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicotine E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "6-methyl-nicotine (metatine) e-cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "34 Years",
        "sex": "ALL",
        "summary": "21 Years to 34 Years"
      },
      "enrollment_count": 53,
      "start_date": "2025-03-03",
      "completion_date": "2025-11-04",
      "has_results": false,
      "last_update_posted_date": "2026-09-08",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06868368"
    },
    {
      "nct_id": "NCT05958966",
      "title": "Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "E-Cig Use",
        "Cigarette Smoking",
        "Cigarette Use, Electronic"
      ],
      "interventions": [
        {
          "name": "E-cigarette e-liquid self-administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 73,
      "start_date": "2022-04-01",
      "completion_date": "2023-05-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-25",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05958966"
    },
    {
      "nct_id": "NCT06027723",
      "title": "Nicotine and Pavlovian Bias",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Nicotine Vaping",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2023-10-25",
      "completion_date": "2024-10-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-09",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06027723"
    },
    {
      "nct_id": "NCT03473483",
      "title": "Cigarette Harm Reduction With Electronic Cigarette Use",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Toxicity",
        "Nicotine Dependence, Cigarettes",
        "Cardiovascular Risk Factor",
        "Nicotine Withdrawal"
      ],
      "interventions": [
        {
          "name": "SREC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-08-01",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-12-09",
      "last_synced_at": "2026-11-15T08:59:47.695Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03473483"
    }
  ]
}