{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Early+Rheumatoid+Arthritis&page=2", "query": { "condition": "Early Rheumatoid Arthritis", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Early+Rheumatoid+Arthritis&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-07-24T07:33:19.312Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00195663", "title": "Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Early Rheumatoid Arthritis" ], "interventions": [ { "name": "Adalimumab", "type": "BIOLOGICAL" }, { "name": "Methotrexate", "type": "DRUG" }, { "name": "Adalimumab placebo", "type": "BIOLOGICAL" }, { "name": "Methotrexate placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "AbbVie (prior sponsor, Abbott)", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 799, "start_date": "2000-12", "completion_date": "2012-04", "has_results": true, "last_update_posted_date": "2013-07-12", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 31, "location_summary": "Scottsdale, Arizona • La Jolla, California • Los Angeles, California + 24 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00195663" }, { "nct_id": "NCT02386527", "title": "Consortium of Early Arthritis Cohorts USA", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [], "intervention_types": [], "sponsor": "Hospital for Special Surgery, New York", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 119, "start_date": "2014-12-01", "completion_date": "2024-04", "has_results": false, "last_update_posted_date": "2025-04-13", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02386527" }, { "nct_id": "NCT00122382", "title": "Remission and Joint Damage Progression in Early Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Abatacept", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" }, { "name": "methotrexate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1052, "start_date": "2005-07", "completion_date": "2009-02", "has_results": true, "last_update_posted_date": "2010-11-16", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 19, "location_summary": "Huntsville, Alabama • Huntington Beach, California • Colorado Springs, Colorado + 15 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Trumbull", "state": "Connecticut" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00122382" }, { "nct_id": "NCT00443430", "title": "Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Juvenile Chronic Polyarthritis", "Juvenile Idiopathic Arthritis", "Juvenile Rheumatoid Arthritis" ], "interventions": [ { "name": "methotrexate", "type": "DRUG" }, { "name": "methotrexate - etanercept - prednisolone arm", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Seattle Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "2 Years to 17 Years" }, "enrollment_count": 85, "start_date": "2007-05", "completion_date": "2010-10", "has_results": true, "last_update_posted_date": "2013-05-31", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 15, "location_summary": "Palo Alto, California • San Diego, California • San Francisco, California + 12 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Hackensack", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00443430" }, { "nct_id": "NCT01519791", "title": "A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Certolizumab Pegol", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Methotrexate", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "UCB Pharma SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 880, "start_date": "2012-01", "completion_date": "2015-09", "has_results": true, "last_update_posted_date": "2018-07-31", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 70, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 63 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Paradise Valley", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01519791" }, { "nct_id": "NCT02504268", "title": "Effects of Abatacept in Patients With Early Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Abatacept", "type": "DRUG" }, { "name": "Methotrexate", "type": "DRUG" }, { "name": "Abatacept Placebo", "type": "OTHER" }, { "name": "Methotrexate Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 994, "start_date": "2015-09-03", "completion_date": "2020-03-19", "has_results": true, "last_update_posted_date": "2021-06-28", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 42, "location_summary": "Huntsville, Alabama • Glendale, Arizona • Mesa, Arizona + 36 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02504268" }, { "nct_id": "NCT06671054", "title": "A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis (RA)" ], "interventions": [ { "name": "AP1189, 40 mg", "type": "DRUG" }, { "name": "AP1189, 70 mg", "type": "DRUG" }, { "name": "AP1189, 100 mg", "type": "DRUG" }, { "name": "AP1189 matching placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "SynAct Pharma Aps", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 240, "start_date": "2024-10-01", "completion_date": "2025-12", "has_results": false, "last_update_posted_date": "2025-10-06", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 3, "location_summary": "Cutler Bay, Florida • Miami, Florida • Duncansville, Pennsylvania", "locations": [ { "city": "Cutler Bay", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Duncansville", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT06671054" }, { "nct_id": "NCT00815425", "title": "Consortium for the Longitudinal Evaluation of African Americans With Early Rheumatoid Arthritis (The CLEAR Registry)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 1613, "start_date": "2000-09", "completion_date": "2012-03", "has_results": false, "last_update_posted_date": "2014-12-02", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00815425" }, { "nct_id": "NCT01007435", "title": "A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Tocilizumab", "type": "DRUG" }, { "name": "Placebo to tocilizumab", "type": "DRUG" }, { "name": "Methotrexate", "type": "DRUG" }, { "name": "Placebo to methotrexate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1162, "start_date": "2009-10-31", "completion_date": "2014-01-28", "has_results": true, "last_update_posted_date": "2017-07-26", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 61, "location_summary": "Anniston, Alabama • Huntsville, Alabama • Tuscaloosa, Alabama + 54 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01007435" }, { "nct_id": "NCT01341314", "title": "Finding Early Rheumatoid Arthritis", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Joint Pain", "Stiffness" ], "interventions": [], "intervention_types": [], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2010-01", "completion_date": "2013-07", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-07-24T07:33:19.312Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01341314" } ] }