{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Early-Onset+Sepses%2C+Neonatal",
    "query": {
      "condition": "Early-Onset Sepses, Neonatal"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:39:16.200Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01825421",
      "title": "A Pilot Randomized Controlled Trial for Antibiotic Exposure in Neonatal Sepsis Using Neutrophil CD64",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Early-onset Sepsis",
        "Neonatal Late-onset Sepsis"
      ],
      "interventions": [
        {
          "name": "Intervention is to stop antibiotics at 24h .",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "5 Months",
        "sex": "ALL",
        "summary": "1 Hour to 5 Months"
      },
      "enrollment_count": 0,
      "start_date": "2014-10",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2020-03-30",
      "last_synced_at": "2026-05-22T03:39:16.200Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01825421"
    },
    {
      "nct_id": "NCT02410486",
      "title": "Early-Onset Sepsis an NICHD/CDC Surveillance Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infant, Newborn, Diseases",
        "Early Onset Neonatal Sepsis",
        "Early-Onset Meningitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 570,
      "start_date": "2015-04",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2019-03-11",
      "last_synced_at": "2026-05-22T03:39:16.200Z",
      "location_count": 20,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02410486"
    },
    {
      "nct_id": "NCT03694613",
      "title": "Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Infant",
        "Early-Onset Neonatal Sepsis",
        "Umbilical Cord"
      ],
      "interventions": [
        {
          "name": "Placental/Umbilical Cord Blood sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Day",
        "sex": "ALL",
        "summary": "Up to 1 Day"
      },
      "enrollment_count": 65,
      "start_date": "2019-06-01",
      "completion_date": "2020-08-20",
      "has_results": true,
      "last_update_posted_date": "2021-08-10",
      "last_synced_at": "2026-05-22T03:39:16.200Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03694613"
    },
    {
      "nct_id": "NCT03997266",
      "title": "NICU Antibiotics and Outcomes Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Microbial Colonization",
        "Extreme Prematurity",
        "Early-Onset Neonatal Sepsis",
        "Late-Onset Neonatal Sepsis",
        "Necrotizing Enterocolitis of Newborn",
        "Death; Neonatal"
      ],
      "interventions": [
        {
          "name": "Ampicillin",
          "type": "DRUG"
        },
        {
          "name": "Gentamycin",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Michael Morowitz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "4 Hours",
        "sex": "ALL",
        "summary": "Up to 4 Hours"
      },
      "enrollment_count": 359,
      "start_date": "2020-08-05",
      "completion_date": "2026-01-15",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T03:39:16.200Z",
      "location_count": 14,
      "location_summary": "Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03997266"
    },
    {
      "nct_id": "NCT04513691",
      "title": "A Chart Review of Newborns With the Presence of Confirmed or Suspected Maternal Chorioamnionitis and Utilization of the Early Onset Sepsis Calculator",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Maternal; Chorioamnionitis, Affecting Fetus",
        "Early-Onset Sepses, Neonatal"
      ],
      "interventions": [
        {
          "name": "EOS Calculator",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Weeks and older"
      },
      "enrollment_count": 236,
      "start_date": "2020-09-30",
      "completion_date": "2022-08-10",
      "has_results": false,
      "last_update_posted_date": "2022-11-22",
      "last_synced_at": "2026-05-22T03:39:16.200Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04513691"
    }
  ]
}