{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ehlers+Danlos+Syndrome&page=2",
    "query": {
      "condition": "Ehlers Danlos Syndrome",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ehlers+Danlos+Syndrome&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T13:27:11.410Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05279937",
      "title": "The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Ehlers-Danlos Syndrome",
        "Low Back Pain",
        "Sacroiliac Instability"
      ],
      "interventions": [
        {
          "name": "Dextrose 50% Intravenous Solution",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine 1% Injectable Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tulane University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-06",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05279937"
    },
    {
      "nct_id": "NCT03602482",
      "title": "Standing Cognition and Co-morbidities of POTS Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postural Tachycardia Syndrome",
        "Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "Standing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Supine",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "13 Years to 60 Years"
      },
      "enrollment_count": 139,
      "start_date": "2018-06-23",
      "completion_date": "2019-12-17",
      "has_results": true,
      "last_update_posted_date": "2021-04-14",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03602482"
    },
    {
      "nct_id": "NCT04734041",
      "title": "Integrative Medicine for Hypermobility Spectrum Disorder and Ehlers-Danlos Syndromes (IMforHSDandEDS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ehlers-Danlos Syndrome",
        "Hypermobile EDS (hEDS)",
        "Hypermobility Syndrome",
        "EDS"
      ],
      "interventions": [
        {
          "name": "Anti-inflammatory (Mediterranean-style) diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral and psychosocial support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National University of Natural Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-12-23",
      "completion_date": "2021-07-02",
      "has_results": false,
      "last_update_posted_date": "2021-07-15",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04734041"
    },
    {
      "nct_id": "NCT05561270",
      "title": "Light Exposure on Pain in Hypermobile Ehlers-Danlos Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ehlers-Danlos Syndrome",
        "Pain, Chronic"
      ],
      "interventions": [
        {
          "name": "White LED light",
          "type": "DEVICE"
        },
        {
          "name": "Green LED light",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2022-11-21",
      "completion_date": "2025-11",
      "has_results": false,
      "last_update_posted_date": "2024-05-06",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05561270"
    },
    {
      "nct_id": "NCT06571721",
      "title": "The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Collagen Degeneration",
        "Wrinkle",
        "Pigmentation",
        "Elastic Skin",
        "Sebum Deficiency"
      ],
      "interventions": [
        {
          "name": "Topical Product: Almond Oil",
          "type": "OTHER"
        },
        {
          "name": "Topical Product: Almond oil augmented with 0.5% Vitamin E",
          "type": "OTHER"
        },
        {
          "name": "Topical Product: 0.025% Tretinoin oil augmented with castor oil",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Integrative Skin Science and Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 90,
      "start_date": "2024-07-22",
      "completion_date": "2025-07-22",
      "has_results": false,
      "last_update_posted_date": "2024-08-28",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06571721"
    },
    {
      "nct_id": "NCT02761928",
      "title": "Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Low Back Pain, Mechanical",
        "Spinal Stenosis",
        "Nerve Root Disorder",
        "Radiculopathy, Cervical",
        "Benign Hypermobility Syndrome"
      ],
      "interventions": [
        {
          "name": "Beighton score for hypermobility",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2016-01",
      "completion_date": "2017-08-01",
      "has_results": false,
      "last_update_posted_date": "2020-11-12",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02761928"
    },
    {
      "nct_id": "NCT05405257",
      "title": "Oxytocin for Hypermobile Ehlers-Danlos Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypermobile Ehlers-Danlos Syndrome",
        "Pain Assessment"
      ],
      "interventions": [
        {
          "name": "Oxytocin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 2,
      "start_date": "2022-05-13",
      "completion_date": "2025-03-11",
      "has_results": true,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05405257"
    },
    {
      "nct_id": "NCT02213484",
      "title": "Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Marfan Syndrome",
        "Loeys-Dietz Syndrome",
        "Thoracic Aortic Aneurysm and Dissection Syndromes",
        "Ehlers-Danlos Type IV Syndrome",
        "Turner Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Days to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2014-07-01",
      "completion_date": "2016-07-01",
      "has_results": false,
      "last_update_posted_date": "2017-03-15",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02213484"
    },
    {
      "nct_id": "NCT03093493",
      "title": "Genetics of Ehlers-Danlos Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Genetics Syndrome",
        "Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "Genotyping",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 334,
      "start_date": "2017-08-25",
      "completion_date": "2025-04-03",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03093493"
    },
    {
      "nct_id": "NCT07565636",
      "title": "3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ehlers-Danlos Syndrome Hypermobility Type (hEDS)"
      ],
      "interventions": [
        {
          "name": "3D scanned and 3D printed wrist hand orthosis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ELewis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2025-08-21",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-06-10T13:27:11.410Z",
      "location_count": 1,
      "location_summary": "Lowell, Massachusetts",
      "locations": [
        {
          "city": "Lowell",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07565636"
    }
  ]
}