{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ehlers-Danlos+Syndrome+%28EDS%29&page=2",
    "query": {
      "condition": "Ehlers-Danlos Syndrome (EDS)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ehlers-Danlos+Syndrome+%28EDS%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:08:40.386Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05405257",
      "title": "Oxytocin for Hypermobile Ehlers-Danlos Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypermobile Ehlers-Danlos Syndrome",
        "Pain Assessment"
      ],
      "interventions": [
        {
          "name": "Oxytocin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 2,
      "start_date": "2022-05-13",
      "completion_date": "2025-03-11",
      "has_results": true,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05405257"
    },
    {
      "nct_id": "NCT06571721",
      "title": "The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Collagen Degeneration",
        "Wrinkle",
        "Pigmentation",
        "Elastic Skin",
        "Sebum Deficiency"
      ],
      "interventions": [
        {
          "name": "Topical Product: Almond Oil",
          "type": "OTHER"
        },
        {
          "name": "Topical Product: Almond oil augmented with 0.5% Vitamin E",
          "type": "OTHER"
        },
        {
          "name": "Topical Product: 0.025% Tretinoin oil augmented with castor oil",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Integrative Skin Science and Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 90,
      "start_date": "2024-07-22",
      "completion_date": "2025-07-22",
      "has_results": false,
      "last_update_posted_date": "2024-08-28",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06571721"
    },
    {
      "nct_id": "NCT01367977",
      "title": "Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ehlers Danlos Syndrome",
        "External Hydrocephalus",
        "Dysautonomia",
        "Postural Orthostatic Tachycardia Syndrome",
        "Venous Insufficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Genetic Disease Investigators",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2011-05",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2024-02-14",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Colleyville, Texas",
      "locations": [
        {
          "city": "Colleyville",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01367977"
    },
    {
      "nct_id": "NCT07464093",
      "title": "STABLE Pilates for Hypermobility",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ehlers-Danlos Syndrome (EDS)",
        "Hypermobile EDS (hEDS)",
        "Hypermobile Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "Pilates",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-08",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Chestnut Hill, Massachusetts",
      "locations": [
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07464093"
    },
    {
      "nct_id": "NCT06105541",
      "title": "Hypermobile Ehlers-Danlos Syndrome - Transcutaneous Auricular Neuromodulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypermobile Ehlers-Danlos Syndrome",
        "Hypermobile Spectrum Disorder",
        "Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Auricular Neurostimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 25,
      "start_date": "2023-07-05",
      "completion_date": "2026-02-04",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06105541"
    },
    {
      "nct_id": "NCT00270686",
      "title": "Studies of Heritable Disorders of Connective Tissue",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ehlers-Danlos Syndrome",
        "Stickler Syndrome",
        "Marfan Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 929,
      "start_date": "2003-01-21",
      "completion_date": "2015-01-02",
      "has_results": false,
      "last_update_posted_date": "2018-04-05",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00270686"
    },
    {
      "nct_id": "NCT04734041",
      "title": "Integrative Medicine for Hypermobility Spectrum Disorder and Ehlers-Danlos Syndromes (IMforHSDandEDS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ehlers-Danlos Syndrome",
        "Hypermobile EDS (hEDS)",
        "Hypermobility Syndrome",
        "EDS"
      ],
      "interventions": [
        {
          "name": "Anti-inflammatory (Mediterranean-style) diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral and psychosocial support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National University of Natural Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-12-23",
      "completion_date": "2021-07-02",
      "has_results": false,
      "last_update_posted_date": "2021-07-15",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04734041"
    },
    {
      "nct_id": "NCT01322165",
      "title": "National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Marfan Syndrome",
        "Turner Syndrome",
        "Ehlers-Danlos Syndrome",
        "Loeys-Dietz Syndrome",
        "FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation",
        "Bicuspid Aortic Valve Without Known Family History",
        "Bicuspid Aortic Valve With Family History",
        "Bicuspid Aortic Valve With Coarctation",
        "Familial Thoracic Aortic Aneurysm and Dissections",
        "Shprintzen-Goldberg Syndrome",
        "Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo",
        "Other Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3706,
      "start_date": "2007-11",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2016-12-20",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 7,
      "location_summary": "Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01322165"
    },
    {
      "nct_id": "NCT05945784",
      "title": "Exploring Accessible Beauty for Individuals With Upper Extremity Deficits",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke, Ischemic",
        "Stroke Hemorrhagic",
        "Stroke (CVA) or TIA",
        "Stroke, Acute",
        "Traumatic Brain Injury",
        "SCI - Spinal Cord Injury",
        "Ehlers-Danlos Syndromes (EDS)",
        "Lupus Erythematosus",
        "Guillain-Barre Syndrome",
        "Multiple Sclerosis",
        "Myasthenia Gravis",
        "Amyotrophic Lateral Sclerosis",
        "Graves Disease",
        "Muscular Dystrophies"
      ],
      "interventions": [
        {
          "name": "Use of Rare Beauty makeup products",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Casa Colina Hospital and Centers for Healthcare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 57,
      "start_date": "2023-07-21",
      "completion_date": "2023-09-29",
      "has_results": false,
      "last_update_posted_date": "2023-12-06",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Pomona, California",
      "locations": [
        {
          "city": "Pomona",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05945784"
    },
    {
      "nct_id": "NCT00001641",
      "title": "Study of Heritable Connective Tissue Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Connective Tissue Disease",
        "Dissecting Aneurysm",
        "Ehlers Danlos Syndrome",
        "Marfan Syndrome",
        "Nail Patella Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 900,
      "start_date": "1997-03",
      "completion_date": "2002-06",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T05:08:40.386Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001641"
    }
  ]
}