{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ehlers-Danlos+Type+IV+Syndrome",
    "query": {
      "condition": "Ehlers-Danlos Type IV Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T10:56:23.211Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05980104",
      "title": "Single-Session \"Empowered Relief\" Class for Marfan Syndrome and Related Conditions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Marfan Syndrome",
        "Vascular Ehlers-Danlos Syndrome",
        "Loeys-Dietz Syndrome"
      ],
      "interventions": [
        {
          "name": "Empowered Relief",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 92,
      "start_date": "2024-03-21",
      "completion_date": "2024-08-31",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-07-22T10:56:23.211Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05980104"
    },
    {
      "nct_id": "NCT05463679",
      "title": "Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome.",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Vascular Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "Enzastaurin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aytu BioPharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 260,
      "start_date": "2025-01",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2024-03-08",
      "last_synced_at": "2026-07-22T10:56:23.211Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05463679"
    },
    {
      "nct_id": "NCT05432466",
      "title": "Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Vascular Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "ACER-002 (celiprolol) 200 mg BID",
          "type": "DRUG"
        },
        {
          "name": "Placebo BID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Acer Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "15 Years to 64 Years"
      },
      "enrollment_count": 150,
      "start_date": "2022-11-07",
      "completion_date": "2029-04-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-24",
      "last_synced_at": "2026-07-22T10:56:23.211Z",
      "location_count": 1,
      "location_summary": "Culver City, California",
      "locations": [
        {
          "city": "Culver City",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05432466"
    },
    {
      "nct_id": "NCT02213484",
      "title": "Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Marfan Syndrome",
        "Loeys-Dietz Syndrome",
        "Thoracic Aortic Aneurysm and Dissection Syndromes",
        "Ehlers-Danlos Type IV Syndrome",
        "Turner Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Days to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2014-07-01",
      "completion_date": "2016-07-01",
      "has_results": false,
      "last_update_posted_date": "2017-03-15",
      "last_synced_at": "2026-07-22T10:56:23.211Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02213484"
    },
    {
      "nct_id": "NCT03440697",
      "title": "Pathogenetic Basis of Aortopathy and Aortic Valve Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortopathies",
        "Thoracic Aortic Aneurysm",
        "Aortic Valve Disease",
        "Thoracic Aortic Disease",
        "Thoracic Aortic Dissection",
        "Thoracic Aortic Rupture",
        "Ascending Aortic Disease",
        "Descending Aortic Disease",
        "Ascending Aortic Aneurysm",
        "Descending Aortic Aneurysm",
        "Marfan Syndrome",
        "Loeys-Dietz Syndrome",
        "Vascular Ehlers-Danlos Syndrome",
        "Shprintzen-Goldberg Syndrome",
        "Turner Syndrome",
        "PHACE Syndrome",
        "Autosomal Recessive Cutis Laxa",
        "Congenital Contractural Arachnodactyly",
        "Arterial Tortuosity Syndrome",
        "Bicuspid Aortic Valve-Associated Aortopathy",
        "Bicuspid Aortic Valve",
        "Familial Thoracic Aortic Aneurysm and Aortic Dissection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3000,
      "start_date": "2015-12-10",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-07-22T10:56:23.211Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440697"
    },
    {
      "nct_id": "NCT05994664",
      "title": "Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vascular Ehlers-Danlos Syndrome"
      ],
      "interventions": [
        {
          "name": "Heartmath Intervention",
          "type": "OTHER"
        },
        {
          "name": "Control Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "12 Years to 45 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-04-01",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-07-22T10:56:23.211Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05994664"
    }
  ]
}