{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Elective+Knee+Surgery", "query": { "condition": "Elective Knee Surgery" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 18, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Elective+Knee+Surgery&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-27T00:21:48.695Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00371683", "title": "Study of Apixaban for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Deep Vein Thrombosis", "Pulmonary Embolism" ], "interventions": [ { "name": "Enoxaparin + Placebo", "type": "DRUG" }, { "name": "Apixaban + Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3608, "start_date": "2006-11", "completion_date": "2008-05", "has_results": true, "last_update_posted_date": "2015-12-30", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 25, "location_summary": "Birmingham, Alabama • Tuscaloosa, Alabama • Little Rock, Arkansas + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00371683" }, { "nct_id": "NCT01184196", "title": "ChloraPrep Versus Betadine for Elective Knee Replacement Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Arthroplasty, Knee Replacement", "Replacement, Total Knee", "Total Knee Replacement" ], "interventions": [ { "name": "Swab area with Betadine", "type": "DRUG" }, { "name": "Swab area with ChloraPrep", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Central DuPage Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 55, "start_date": "2009-11", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2013-04-16", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 1, "location_summary": "Winfield, Illinois", "locations": [ { "city": "Winfield", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01184196" }, { "nct_id": "NCT00362232", "title": "Regulation of Coagulation in Orthopedic Surgery to Prevent Deep Vein Thromboembolism (DVT) and Pulmonary Embolism (PE). A Study of BAY59-7939 in the Prevention of Venous Thrombo Embolism (VTE) in Subjects Undergoing Elective Total Knee Replacement.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Venous Thromboembolism" ], "interventions": [ { "name": "Rivaroxaban (Xarelto, BAY59-7939)", "type": "DRUG" }, { "name": "Enoxaparin", "type": "DRUG" }, { "name": "Placebo: tablet of Rivaroxaban", "type": "DRUG" }, { "name": "Placebo: syringes of Enoxaparin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3148, "start_date": "2006-06", "completion_date": "2008-01", "has_results": true, "last_update_posted_date": "2014-11-04", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 40, "location_summary": "Birmingham, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 36 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00362232" }, { "nct_id": "NCT01196169", "title": "Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Staphylococcal Infections", "Methicillin-resistant Staphylococcus Aureus" ], "interventions": [ { "name": "Daptomycin", "type": "DRUG" }, { "name": "Vancomycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mountain Home Research & Education Corporation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 28, "start_date": "2010-10", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2014-02-03", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 2, "location_summary": "Johnson City, Tennessee • Mountain Home, Tennessee", "locations": [ { "city": "Johnson City", "state": "Tennessee" }, { "city": "Mountain Home", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01196169" }, { "nct_id": "NCT03166462", "title": "Obstructive Sleep Apnea in Elective Orthopaedic Surgery", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sleep Apnea, Obstructive", "Total Knee Arthroplasty", "Total Hip Arthroplasty" ], "interventions": [ { "name": "Evaluation by Sleep Medicine Specialists", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2018-02-08", "completion_date": "2018-02-08", "has_results": false, "last_update_posted_date": "2018-03-09", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03166462" }, { "nct_id": "NCT03251482", "title": "A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery" ], "interventions": [ { "name": "JNJ-64179375 0.3 mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 0.6 mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 1.2 mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 (Dose to be Determined)", "type": "DRUG" }, { "name": "JNJ-64179375 A mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 B mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 C mg/kg", "type": "DRUG" }, { "name": "JNJ-64179375 D mg/kg", "type": "DRUG" }, { "name": "Placebo JNJ-64179375", "type": "DRUG" }, { "name": "Apixaban placebo", "type": "DRUG" }, { "name": "Apixaban 2.5 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 308, "start_date": "2017-11-13", "completion_date": "2018-11-05", "has_results": true, "last_update_posted_date": "2019-11-25", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Torrance, California • Englewood, Colorado + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Torrance", "state": "California" }, { "city": "Englewood", "state": "Colorado" }, { "city": "DeLand", "state": "Florida" }, { "city": "Pensacola", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03251482" }, { "nct_id": "NCT03601728", "title": "A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Arthropathy of Knee Joint", "Arthropathy of Hip Joint" ], "interventions": [ { "name": "personalized prehabilitation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": null, "sex": "ALL", "summary": "55 Years and older" }, "enrollment_count": 28, "start_date": "2019-10-01", "completion_date": "2029-12-31", "has_results": false, "last_update_posted_date": "2026-05-29", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03601728" }, { "nct_id": "NCT03891524", "title": "A Study of JNJ-70033093 (BMS-986177) Versus Subcutaneous Enoxaparin in Participants Undergoing Elective Total Knee Replacement Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Arthroplasty, Replacement, Knee" ], "interventions": [ { "name": "JNJ-70033093 25 mg", "type": "DRUG" }, { "name": "JNJ-70033093 50 mg", "type": "DRUG" }, { "name": "JNJ-70033093 100 mg", "type": "DRUG" }, { "name": "JNJ-70033093 200 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Enoxaparin 40 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 1242, "start_date": "2019-06-17", "completion_date": "2021-04-06", "has_results": true, "last_update_posted_date": "2025-03-30", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 9, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 6 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Torrance", "state": "California" }, { "city": "Englewood", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03891524" }, { "nct_id": "NCT02080481", "title": "Needle Guidance in Ultrasound Guided Nerve Blocks", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Elective Knee Surgery" ], "interventions": [ { "name": "Infiniti Plus needle guidance system", "type": "DEVICE" }, { "name": "Conventional block needle", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 135, "start_date": "2014-03", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2017-05-15", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02080481" }, { "nct_id": "NCT05934500", "title": "CBD Knee Scope Study", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Post-operative Pain" ], "interventions": [ { "name": "Cannabidiol Oil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Foundation for Orthopaedic Research and Education", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2023-10-15", "completion_date": "2025-12-30", "has_results": false, "last_update_posted_date": "2023-09-13", "last_synced_at": "2026-06-27T00:21:48.695Z", "location_count": 1, "location_summary": "Tampa, Florida", "locations": [ { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05934500" } ] }