{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Electrolyte+Changes", "query": { "condition": "Electrolyte Changes" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Electrolyte+Changes&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-22T07:05:56.581Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06212518", "title": "Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dehydration" ], "interventions": [ { "name": "GENPOP ad libitum fluid intake", "type": "OTHER" }, { "name": "GENPOP fluid restriction", "type": "OTHER" }, { "name": "ATHLETE ad libitum fluid intake", "type": "OTHER" }, { "name": "ATHLETE restricted fluid intake", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "PepsiCo Global R&D", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "14 Years to 65 Years" }, "enrollment_count": 1000, "start_date": "2023-10-02", "completion_date": "2024-08-31", "has_results": false, "last_update_posted_date": "2024-01-19", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 4, "location_summary": "Bradenton, Florida • Chicago, Illinois • Valhalla, New York + 1 more", "locations": [ { "city": "Bradenton", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Valhalla", "state": "New York" }, { "city": "Plano", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06212518" }, { "nct_id": "NCT06042270", "title": "Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Body Temperature Changes", "Body Water Dehydration", "Inflammation" ], "interventions": [ { "name": "Betaine", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Michael J. Ormsbee", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 17, "start_date": "2023-12-20", "completion_date": "2024-09-01", "has_results": false, "last_update_posted_date": "2024-10-17", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Tallahassee, Florida", "locations": [ { "city": "Tallahassee", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06042270" }, { "nct_id": "NCT05814146", "title": "Trial of Variable Dialysate Bicarbonate", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Peri-dialytic Cardiac Rhythms", "Intradialytic Hypotension", "Electrolyte Changes", "pH Changes", "Adverse Symptoms" ], "interventions": [ { "name": "Dialysate bicarbonate concentration", "type": "DRUG" }, { "name": "Dialysate bicarbonate concentration - telemetry monitoring", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 141, "start_date": "2023-08-24", "completion_date": "2026-10-01", "has_results": false, "last_update_posted_date": "2025-11-24", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05814146" }, { "nct_id": "NCT04613856", "title": "Water Bolus Volumes During Continuous Exercise in Heat", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dehydration (Physiology)", "Hyperthermia" ], "interventions": [ { "name": "Hydration protocol - 237 mL water bolus", "type": "OTHER" }, { "name": "Hydration protocol - 500 mL water bolus", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "State University of New York at Buffalo", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "39 Years", "sex": "MALE", "summary": "18 Years to 39 Years · Male only" }, "enrollment_count": 16, "start_date": "2019-04-17", "completion_date": "2020-03-12", "has_results": false, "last_update_posted_date": "2020-11-03", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04613856" }, { "nct_id": "NCT04393909", "title": "Improving Safety of Diagnosis and Therapy in the Inpatient Setting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Delirium", "Confusion", "Mental Status Change", "Back Pain", "Hip Pain Chronic", "Chest Pain", "Asthma", "COPD", "Cellulitis", "Soft Tissue Infections", "Cough", "Deep Vein Thrombosis", "Pulmonary Embolism", "Venous Thromboembolism", "Dyspnea", "Electrolyte Metabolism Abnormal", "Fever", "Failure to Thrive", "Weakness", "Protein-Calorie Malnutrition", "Headache", "Neck Pain", "Hypoxia", "Pneumonia", "Sepsis", "Syncope", "Vomiting", "Diarrhea", "Leg Pain", "Abdominal Pain" ], "interventions": [ { "name": "Diagnostic Uncertainty Educational Curriculum", "type": "BEHAVIORAL" }, { "name": "Diagnostic Timeout", "type": "BEHAVIORAL" }, { "name": "Patient Diagnostic (Dx) Questionnaire", "type": "BEHAVIORAL" }, { "name": "Enhancements to Epic-integrated Quality & Safety Dashboard", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 700, "start_date": "2019-07-01", "completion_date": "2021-12-30", "has_results": false, "last_update_posted_date": "2022-07-26", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04393909" }, { "nct_id": "NCT01283152", "title": "Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hepatic Encephalopathy", "Cirrhosis", "Portosystemic Encephalopathy", "PSE" ], "interventions": [ { "name": "Polyethylene glycol 3350-electrolyte solution (GoLYTELY®)", "type": "DRUG" }, { "name": "Lactulose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 50, "start_date": "2011-01", "completion_date": "2012-06", "has_results": true, "last_update_posted_date": "2014-12-11", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01283152" }, { "nct_id": "NCT05174793", "title": "Using Urine Color as a Marker of Hydration Status", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dehydration" ], "interventions": [ { "name": "dehydration and rehydration", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "San Diego State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "18 Years to 35 Years" }, "enrollment_count": 10, "start_date": "2020-03-15", "completion_date": "2020-11-15", "has_results": false, "last_update_posted_date": "2022-01-03", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05174793" }, { "nct_id": "NCT04233957", "title": "Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sodium Excess" ], "interventions": [ { "name": "High Sodium", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "University of Delaware", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "21 Years to 45 Years" }, "enrollment_count": 50, "start_date": "2020-01-01", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2023-11-29", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Newark, Delaware", "locations": [ { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT04233957" }, { "nct_id": "NCT04598386", "title": "The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Fluid Retention", "Fluid Loss", "Sodium Retention", "Cognitive Change", "Heat Exposure", "Hyperhydration", "Electrolyte and Fluid Balance Conditions" ], "interventions": [ { "name": "PR Lotion - AMP Human Performance", "type": "OTHER" }, { "name": "Placebo Lotion", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Connecticut", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "MALE", "summary": "18 Years to 35 Years · Male only" }, "enrollment_count": 20, "start_date": "2020-12-09", "completion_date": "2021-04-09", "has_results": false, "last_update_posted_date": "2021-10-14", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Storrs, Connecticut", "locations": [ { "city": "Storrs", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT04598386" }, { "nct_id": "NCT05458843", "title": "Renal Considerations in the Heat Stress Recommendations (Aim2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hot Weather; Adverse Effect", "Kidney Dysfunction", "Kidney Injury", "Hyperthermia", "Dehydration" ], "interventions": [ { "name": "Fluid replacement", "type": "PROCEDURE" }, { "name": "No fluid replacement", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "44 Years", "sex": "ALL", "summary": "18 Years to 44 Years" }, "enrollment_count": 18, "start_date": "2022-08-01", "completion_date": "2023-05-22", "has_results": false, "last_update_posted_date": "2023-11-08", "last_synced_at": "2026-07-22T07:05:56.581Z", "location_count": 1, "location_summary": "Bloomington, Indiana", "locations": [ { "city": "Bloomington", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05458843" } ] }