{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Electronic+Nicotine+Delivery+Systems",
    "query": {
      "condition": "Electronic Nicotine Delivery Systems"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 46,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Electronic+Nicotine+Delivery+Systems&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-21T08:23:01.814Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05383508",
      "title": "Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Vaping",
        "Nicotine",
        "Vaping"
      ],
      "interventions": [
        {
          "name": "CA35",
          "type": "OTHER"
        },
        {
          "name": "CM35",
          "type": "OTHER"
        },
        {
          "name": "Cig",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Philip Morris Products S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "24 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-04-28",
      "completion_date": "2022-08-25",
      "has_results": true,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05383508"
    },
    {
      "nct_id": "NCT03962660",
      "title": "Harm Reduction for Tobacco Smoking With Support of Tobacco-Replacing Electronic Nicotine Delivery Systems",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Tobacco"
      ],
      "interventions": [
        {
          "name": "HaRTS-TRENDS",
          "type": "OTHER"
        },
        {
          "name": "Standard Care (SC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 94,
      "start_date": "2019-05-09",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-05-24",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03962660"
    },
    {
      "nct_id": "NCT04709471",
      "title": "E-cigarette Nicotine Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Electronic Cigarette Use",
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "Juul e-cigarette",
          "type": "DEVICE"
        },
        {
          "name": "Reduction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 77,
      "start_date": "2021-01-20",
      "completion_date": "2022-06-01",
      "has_results": false,
      "last_update_posted_date": "2022-08-26",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04709471"
    },
    {
      "nct_id": "NCT01898169",
      "title": "Evaluation of Short-term Safety and Use Patterns of an Electronic Nicotine Delivery System",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "NJOY King 26 mg nicotine Electronic Nicotine Delivery System",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "LA Clinical Trials",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 33,
      "start_date": "2013-04",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2013-07-12",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Burbank, California",
      "locations": [
        {
          "city": "Burbank",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01898169"
    },
    {
      "nct_id": "NCT05278065",
      "title": "E-cigarettes for Harm Reduction in Adults With Asthma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Asthma",
        "Electronic Cigarette Use",
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 17,
      "start_date": "2022-05-01",
      "completion_date": "2024-09-12",
      "has_results": true,
      "last_update_posted_date": "2025-11-18",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05278065"
    },
    {
      "nct_id": "NCT05423340",
      "title": "Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "E-cigarette Flavor",
          "type": "OTHER"
        },
        {
          "name": "Tobacco Free Nicotine Pouch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Roswell Park Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 163,
      "start_date": "2022-06-12",
      "completion_date": "2024-10-03",
      "has_results": true,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05423340"
    },
    {
      "nct_id": "NCT05134415",
      "title": "Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "RELX ENDS Tobacco Flavor 1",
          "type": "OTHER"
        },
        {
          "name": "RELX ENDS Tobacco Flavor 2",
          "type": "OTHER"
        },
        {
          "name": "RELX ENDS Menthol Flavor 1",
          "type": "OTHER"
        },
        {
          "name": "RELX ENDS Menthol Flavor 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cheerain HK Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-10-12",
      "completion_date": "2021-12-01",
      "has_results": false,
      "last_update_posted_date": "2021-12-13",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Burbank, California",
      "locations": [
        {
          "city": "Burbank",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05134415"
    },
    {
      "nct_id": "NCT05023096",
      "title": "Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Nicotine Delivery System Flavors"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 71,
      "start_date": "2022-04-14",
      "completion_date": "2024-10-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05023096"
    },
    {
      "nct_id": "NCT03575468",
      "title": "Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Enhanced E-cigarette Coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quitline treatment as usual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Consumer Wellness Solutions",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2018-05-07",
      "completion_date": "2020-10-01",
      "has_results": true,
      "last_update_posted_date": "2023-10-16",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03575468"
    },
    {
      "nct_id": "NCT01989923",
      "title": "Smoking Cessation in Women With Gynecological Conditions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Dysplasia"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement Therapy",
          "type": "OTHER"
        },
        {
          "name": "Electronic Cigarettes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 31,
      "start_date": "2013-06",
      "completion_date": "2017-04-13",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-07-21T08:23:01.814Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01989923"
    }
  ]
}