{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Emotional+Instability",
    "query": {
      "condition": "Emotional Instability"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 37,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Emotional+Instability&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T11:47:59.224Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02078596",
      "title": "Depakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood Swings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Irritable Aggression"
      ],
      "interventions": [
        {
          "name": "Divalproex",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "7 Years to 11 Years"
      },
      "enrollment_count": 15,
      "start_date": "1997-03",
      "completion_date": "2004-03",
      "has_results": false,
      "last_update_posted_date": "2017-01-04",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02078596"
    },
    {
      "nct_id": "NCT00475189",
      "title": "Study of Loestrin 24(24 Days of \"Real\" Pills) Fe Versus Loestrin 1/20 (21 \"Real\" Pills)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Pain",
        "Headaches",
        "Emotional"
      ],
      "interventions": [
        {
          "name": "loestrin 24/4 vs loestrin 1/20",
          "type": "DRUG"
        },
        {
          "name": "loestrin 1/20",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Scott and White Hospital & Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "48 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 48 Years · Female only"
      },
      "enrollment_count": 51,
      "start_date": "2007-06",
      "completion_date": "2008-11",
      "has_results": false,
      "last_update_posted_date": "2011-07-25",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "Temple, Texas",
      "locations": [
        {
          "city": "Temple",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475189"
    },
    {
      "nct_id": "NCT00104442",
      "title": "Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Rivastigmine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2003-10",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2007-12-21",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "East Hanover, New Jersey",
      "locations": [
        {
          "city": "East Hanover",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00104442"
    },
    {
      "nct_id": "NCT00021697",
      "title": "Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "AVP-923",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Avanir Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2001-01",
      "completion_date": "2002-04",
      "has_results": false,
      "last_update_posted_date": "2016-07-14",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 17,
      "location_summary": "Loma Linda, California • Los Angeles, California • San Francisco, California + 13 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00021697"
    },
    {
      "nct_id": "NCT00526266",
      "title": "Evaluating Physiological Markers of Emotional Trauma: A Randomized Controlled Comparison of Mind-Body Therapies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypermobility, Joint",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Emotional Freedom Techniques (EFT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Diaphragmatic Breathing (DB)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Soul Medicine Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 37,
      "start_date": "2007-09",
      "completion_date": "2018-01",
      "has_results": false,
      "last_update_posted_date": "2018-04-25",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "Santa Rosa, California",
      "locations": [
        {
          "city": "Santa Rosa",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00526266"
    },
    {
      "nct_id": "NCT06535698",
      "title": "Evaluating the Effect of a Supplement on Symptoms of Hormonal Imbalance.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Women's Health"
      ],
      "interventions": [
        {
          "name": "Perelel Health Hormonal Balance Support",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Perelel Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 35,
      "start_date": "2024-02-19",
      "completion_date": "2024-06-10",
      "has_results": false,
      "last_update_posted_date": "2024-08-02",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06535698"
    },
    {
      "nct_id": "NCT06939972",
      "title": "A Single Group Study to Evaluate the Effects of a Topical Product on Cramps Associated With the Menstrual Cycle",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dysmenorrhea",
        "Menstrual Cramps"
      ],
      "interventions": [
        {
          "name": "Topical Analgesic with Camphor and Menthol",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Rael",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2024-10-03",
      "completion_date": "2024-12-25",
      "has_results": false,
      "last_update_posted_date": "2025-04-23",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06939972"
    },
    {
      "nct_id": "NCT01217775",
      "title": "Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Premenstrual Dysphoric Disorder"
      ],
      "interventions": [
        {
          "name": "PH80",
          "type": "DRUG"
        },
        {
          "name": "Placebo intranasal spray",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pherin Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "43 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 43 Years · Female only"
      },
      "enrollment_count": 1400,
      "start_date": "2016-03",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2015-12-03",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01217775"
    },
    {
      "nct_id": "NCT01408589",
      "title": "A Dose Response Effect of Atomoxetine to the Acute Effects of Alcohol",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alcohol Craving",
        "Mood Changes"
      ],
      "interventions": [
        {
          "name": "Atomoxetine, Strattera",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Boulder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 86,
      "start_date": "2005-06",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2011-08-03",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01408589"
    },
    {
      "nct_id": "NCT05427123",
      "title": "Children's Bipolar Network Treatment Trial I",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bipolar Disorder",
        "Bipolar I Disorder",
        "Bipolar II Disorder",
        "Other Specified Bipolar and Related Disorder",
        "Mood Instability",
        "Child Mental Disorder",
        "Adolescent - Emotional Problem"
      ],
      "interventions": [
        {
          "name": "Medication or psychosocial treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "9 Years to 19 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-07-01",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-06-10T11:47:59.224Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Pittsburgh, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05427123"
    }
  ]
}