{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=End+Stage+Heart+Disease&page=3",
    "query": {
      "condition": "End Stage Heart Disease",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 62,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=End+Stage+Heart+Disease&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=End+Stage+Heart+Disease&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T00:09:54.984Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02858778",
      "title": "Timing of Acute Palliative Care Consultation in Critically Ill Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Organ Failure",
        "End Stage Cardiac Failure",
        "End Stage Chronic Obstructive Airways Disease",
        "Chronic Kidney Disease Stage 5",
        "Hepatic Encephalopathy",
        "Sepsis",
        "Dementia",
        "Multiple Sclerosis",
        "Parkinson's Disease",
        "In-Hospital Cardiac Arrest",
        "Solid Organ Cancer"
      ],
      "interventions": [
        {
          "name": "Early order of palliative care consultation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2016-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-08-08",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 2,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02858778"
    },
    {
      "nct_id": "NCT06383390",
      "title": "The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atherosclerotic Cardiovascular Disease (ASCVD)",
        "Chronic Kidney Disease (CKD)"
      ],
      "interventions": [
        {
          "name": "Retatrutide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2024-04-30",
      "completion_date": "2029-02",
      "has_results": false,
      "last_update_posted_date": "2026-09-24",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 204,
      "location_summary": "Alabaster, Alabama • Birmingham, Alabama • Daphne, Alabama + 159 more",
      "locations": [
        {
          "city": "Alabaster",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Daphne",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06383390"
    },
    {
      "nct_id": "NCT00869024",
      "title": "Stem Cell Therapy in Patients With Severe Heart Failure & Undergoing Left Ventricular Assist Device Placement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Intramyocardial Delivery of Bone Marrow Derived Mononuclear Cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 25,
      "start_date": "2011-11-10",
      "completion_date": "2016-03-29",
      "has_results": true,
      "last_update_posted_date": "2020-03-13",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00869024"
    },
    {
      "nct_id": "NCT01427374",
      "title": "Risk Factors for Coronary Artery Calcification and Left Ventricular Hypertrophy in Hemodialysis Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "End Stage Renal Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Alberta",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2011-05",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-05-01",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 3,
      "location_summary": "Indianapolis, Indiana • Boston, Massachusetts • Seattle, Washington",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01427374"
    },
    {
      "nct_id": "NCT03571672",
      "title": "DEF-314 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cardiac Disease"
      ],
      "interventions": [
        {
          "name": "DEFINITY",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Lantheus Medical Imaging",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2018-10-24",
      "completion_date": "2019-08-30",
      "has_results": true,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 9,
      "location_summary": "Tucson, Arizona • San Diego, California • Wilmington, Delaware + 6 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03571672"
    },
    {
      "nct_id": "NCT01985360",
      "title": "ISCHEMIA-Chronic Kidney Disease Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Coronary Artery Disease",
        "Heart Diseases",
        "Myocardial Ischemia",
        "Kidney Disease",
        "End Stage Renal Failure on Dialysis"
      ],
      "interventions": [
        {
          "name": "Cardiac Catheterization",
          "type": "PROCEDURE"
        },
        {
          "name": "Coronary Artery Bypass Graft Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Percutaneous Coronary Intervention",
          "type": "PROCEDURE"
        },
        {
          "name": "Lifestyle",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Medication",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 777,
      "start_date": "2014-01",
      "completion_date": "2020-07",
      "has_results": true,
      "last_update_posted_date": "2021-10-18",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01985360"
    },
    {
      "nct_id": "NCT07416734",
      "title": "RCT of HeartBot in Women",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Participants Must be Women Aged 25 Years or Older",
        "Participants Should Have no Self-reported History of Heart Disease or Stroke",
        "Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease",
        "Participants Should Not be a Healthcare Professionals or Healthcare Trainees",
        "Participants Should Not be Employed in the Healthcare Field",
        "Participants Should Reside in the United States and be a University of California, San Francisco Health Patient",
        "Participants Should Possess a Smartphone With an Active Data Plan or Access to Wi-Fi"
      ],
      "interventions": [
        {
          "name": "HeartBot II Program",
          "type": "OTHER"
        },
        {
          "name": "Waitlist Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "25 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2026-03-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07416734"
    },
    {
      "nct_id": "NCT04141891",
      "title": "Advancing Understanding of Transportation Options",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Retinopathy",
        "Macular Degeneration",
        "Glaucoma",
        "Retinitis Pigmentosa",
        "Vision Disorders",
        "Acute Coronary Syndrome",
        "Implantable Defibrillator User",
        "Congestive Heart Failure",
        "Hypertrophic Obstructive Cardiomyopathy",
        "Orthostatic Hypotension",
        "Syncope",
        "Presyncope",
        "Narcolepsy",
        "Dementia",
        "Multiple Sclerosis",
        "Parkinson Disease",
        "Brain Injuries",
        "Spinal Cord Injuries",
        "Stroke",
        "Vertigo",
        "Dizziness",
        "Seizures",
        "Substance Use",
        "Insulin Dependent Diabetes Mellitus",
        "Arthritis",
        "Foot--Abnormalities",
        "Chronic Obstructive Pulmonary Disease",
        "Obstructive Sleep Apnea",
        "End Stage Renal Disease",
        "Sleep Apnea",
        "Insomnia",
        "Restless Legs Syndrome"
      ],
      "interventions": [
        {
          "name": "Driving Decision Aid",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Older Drivers Website",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 529,
      "start_date": "2019-12-12",
      "completion_date": "2023-12-21",
      "has_results": true,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 3,
      "location_summary": "La Jolla, California • Aurora, Colorado • Indianapolis, Indiana",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04141891"
    },
    {
      "nct_id": "NCT02285920",
      "title": "Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "End-Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Spironolactone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 129,
      "start_date": "2014-11",
      "completion_date": "2017-07-30",
      "has_results": true,
      "last_update_posted_date": "2019-07-23",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 4,
      "location_summary": "Washington D.C., District of Columbia • Boston, Massachusetts • Nashville, Tennessee + 1 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02285920"
    },
    {
      "nct_id": "NCT06800716",
      "title": "Impella Reverse Remodeling in End-Stage Heart Failure",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure",
        "Cardiomyopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-12-04",
      "completion_date": "2029-11",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-06T00:09:54.984Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06800716"
    }
  ]
}