{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=End-stage+Disease&page=35",
    "query": {
      "condition": "End-stage Disease",
      "page": 35
    },
    "page_size": 10
  },
  "pagination": {
    "page": 35,
    "page_size": 10,
    "total_count": 853,
    "total_pages": 86,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=End-stage+Disease&page=36&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=End-stage+Disease&page=34&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-28T09:25:35.023Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02278562",
      "title": "Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "ESRD"
      ],
      "interventions": [
        {
          "name": "anakinra",
          "type": "DRUG"
        },
        {
          "name": "actos",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2014-10-22",
      "completion_date": "2017-03-01",
      "has_results": true,
      "last_update_posted_date": "2025-02-06",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02278562"
    },
    {
      "nct_id": "NCT04985383",
      "title": "Study to Compare Safety and Tolerability of AKST1210 Column at 2 Blood Flow Rates in Subjects With ESRD on Hemodialysis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End-Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "AKST1210 S-15 at 250 mL/min",
          "type": "DEVICE"
        },
        {
          "name": "AKST1210 S-15 at 450 mL/min",
          "type": "DEVICE"
        },
        {
          "name": "AKST1210 S-25 at 250 mL/min",
          "type": "DEVICE"
        },
        {
          "name": "AKST1210 S-25 at 450 mL/min",
          "type": "DEVICE"
        },
        {
          "name": "AKST1210 S-35 at 250 mL/min",
          "type": "DEVICE"
        },
        {
          "name": "AKST1210 S-35 at 450 mL/min",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alkahest, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-03-11",
      "completion_date": "2021-09-01",
      "has_results": true,
      "last_update_posted_date": "2023-09-29",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 4,
      "location_summary": "Granada Hills, California • Northridge, California • Gallup, New Mexico + 1 more",
      "locations": [
        {
          "city": "Granada Hills",
          "state": "California"
        },
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "Gallup",
          "state": "New Mexico"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04985383"
    },
    {
      "nct_id": "NCT03636269",
      "title": "CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Uremic Pruritus"
      ],
      "interventions": [
        {
          "name": "CR845 0.5 mcg/kg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cara Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 473,
      "start_date": "2018-07-17",
      "completion_date": "2020-03-30",
      "has_results": true,
      "last_update_posted_date": "2022-04-26",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 29,
      "location_summary": "Chula Vista, California • Fountain Valley, California • Northridge, California + 25 more",
      "locations": [
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        },
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "Riverside",
          "state": "California"
        },
        {
          "city": "San Dimas",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03636269"
    },
    {
      "nct_id": "NCT03665454",
      "title": "PF 06412562 in Subjects With Advanced Stage Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "PF-06412562",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 8,
      "start_date": "2018-09-24",
      "completion_date": "2019-04-21",
      "has_results": false,
      "last_update_posted_date": "2019-07-31",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03665454"
    },
    {
      "nct_id": "NCT03300024",
      "title": "Bovine Carotid Artery Biologic Graft and Expanded Polytetrafluoroethylene for Permanent Hemodialysis Access",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Renal Disease",
        "Hemolysis",
        "Arteriovenous Graft"
      ],
      "interventions": [
        {
          "name": "Expanded polytetrafluoroethylene Graft",
          "type": "DEVICE"
        },
        {
          "name": "Bovine Carotid Artery Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 10,
      "start_date": "2015-02-01",
      "completion_date": "2018-02-12",
      "has_results": true,
      "last_update_posted_date": "2019-05-21",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03300024"
    },
    {
      "nct_id": "NCT02526680",
      "title": "Does Using a Low Vision Aid Device Improve Quality of Life in Glaucoma Patients?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "OrCam",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2014-05",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2018-12-13",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02526680"
    },
    {
      "nct_id": "NCT05285436",
      "title": "A Prospective Clinical Study to Assess the Clinical Utility of Turbidity in Patients Using In-Home Peritoneal Dialysis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Renal Disease",
        "Peritoneal Dialysis-associated Peritonitis",
        "Peritonitis"
      ],
      "interventions": [
        {
          "name": "CloudCath System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CloudCath",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 314,
      "start_date": "2022-03-16",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 1,
      "location_summary": "Chicopee, Massachusetts",
      "locations": [
        {
          "city": "Chicopee",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05285436"
    },
    {
      "nct_id": "NCT01660243",
      "title": "Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Uremic Pruritus"
      ],
      "interventions": [
        {
          "name": "Nalfurafine hydrochloride(MT-9938) 2.5μg",
          "type": "DRUG"
        },
        {
          "name": "Nalfurafine hydrochloride(MT-9938) 5μg",
          "type": "DRUG"
        },
        {
          "name": "Nalfurafine hydrochloride(MT-9938) 10μg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Toray Industries, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2012-09",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2022-02-09",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • New York, New York • Rosedale, New York + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rosedale",
          "state": "New York"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01660243"
    },
    {
      "nct_id": "NCT06938542",
      "title": "Palliative Care Needs of Children With Rare Diseases and Their Families",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trisomy 13 Syndrome",
        "Arthrogryposis Congenita Multiplex With Intestinal Atresia",
        "Asparagine Synthetase Deficiency",
        "CHARGE Syndrome",
        "Early Infantile Epileptic Encephalopathy",
        "FOXG1 Syndrome",
        "KBG Syndrome",
        "Noonan Syndrome",
        "Severe Hemophilia A",
        "Short Bowel Syndrome",
        "Beta-Propeller Protein-Associated Neurodegeneration",
        "Brain Injury of Prematurity With Periventricular Leukomalacia",
        "Chromosome 17p13.3 Microdeletion Syndrome",
        "Chromosome 1q43-1q44 Deletion",
        "Cockayne Syndrome",
        "Congenital Diaphragmatic Hernia",
        "End-Stage Renal Disease With Cloacal Anomaly",
        "Mitochondrial Depletion Disorder",
        "Severe Factor VII Deficiency"
      ],
      "interventions": [
        {
          "name": "Family Centered pediatric palliative care for family caregivers of children with rare diseases.",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "12 Months to 99 Years"
      },
      "enrollment_count": 480,
      "start_date": "2025-10-02",
      "completion_date": "2029-08-02",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06938542"
    },
    {
      "nct_id": "NCT03925168",
      "title": "Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Renal Disease",
        "Depression",
        "Anxiety",
        "Major Depressive Disorder",
        "Generalized Anxiety Disorder",
        "Compliance, Patient",
        "Compliance, Medication",
        "Mood",
        "Pain",
        "Energy Supply; Deficiency",
        "Quality of Life",
        "Blood Pressure",
        "Heart Rate Fast"
      ],
      "interventions": [
        {
          "name": "Music therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Tulane University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2019-03-08",
      "completion_date": "2020-01-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-15",
      "last_synced_at": "2026-10-28T09:25:35.023Z",
      "location_count": 3,
      "location_summary": "New Orleans, Louisiana • Terrytown, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Terrytown",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03925168"
    }
  ]
}