{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endocarditis", "query": { "condition": "Endocarditis" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 27, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endocarditis&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-21T22:17:54.806Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03148756", "title": "Efficacy and Safety of Dalbavancin Compared to Standard of Care Antibiotic Therapy for the Completion of Treatment of Patients With Complicated Bacteremia or Infective Endocarditis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Endocarditis", "Bacteremia" ], "interventions": [ { "name": "Dalbavancin", "type": "DRUG" }, { "name": "Standard of Care", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2, "start_date": "2017-05-12", "completion_date": "2017-08-04", "has_results": true, "last_update_posted_date": "2022-04-25", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 1, "location_summary": "Ft. Pierce, Florida", "locations": [ { "city": "Ft. Pierce", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03148756" }, { "nct_id": "NCT05721781", "title": "Reducing Risk for Infective Endocarditis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bacteremia", "Infective Endocarditis" ], "interventions": [ { "name": "Oral Hygiene instruction", "type": "BEHAVIORAL" }, { "name": "Dental Cleaning", "type": "PROCEDURE" } ], "intervention_types": [ "BEHAVIORAL", "PROCEDURE" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 320, "start_date": "2023-08-31", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2025-08-22", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 6, "location_summary": "Boston, Massachusetts • Ann Arbor, Michigan • Newark, New Jersey + 3 more", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Newark", "state": "New Jersey" }, { "city": "New York", "state": "New York" }, { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05721781" }, { "nct_id": "NCT01431326", "title": "Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Adenovirus", "Anesthesia", "Anxiety", "Anxiolysis", "Autism", "Autistic Disorder", "Bacterial Meningitis", "Bacterial Septicemia", "Benzodiazepine", "Bipolar Disorder", "Bone and Joint Infections", "Central Nervous System Infections", "Convulsions", "Cytomegalovirus Retinitis", "Early-onset Schizophrenia Spectrum Disorders", "Epilepsy", "General Anesthesia", "Gynecologic Infections", "Herpes Simplex Virus", "Infantile Hemangioma", "Infection", "Inflammation", "Inflammatory Conditions", "Intra-abdominal Infections", "Lower Respiratory Tract Infections", "Migraines", "Pain", "Pneumonia", "Schizophrenia", "Sedation", "Seizures", "Skeletal Muscle Spasms", "Skin and Skin-structure Infections", "Treatment-resistant Schizophrenia", "Urinary Tract Infections", "Withdrawal", "Sepsis", "Gram-negative Infection", "Bradycardia", "Cardiac Arrest", "Cardiac Arrhythmia", "Staphylococcal Infections", "Nosocomial Pneumonia", "Neuromuscular Blockade", "Methicillin Resistant Staphylococcus Aureus", "Endocarditis", "Neutropenia", "Headache", "Fibrinolytic Bleeding", "Pulmonary Arterial Hypertension", "CMV Retinitis", "Hypertension", "Chronic Kidney Diseases", "Hyperaldosteronism", "Hypokalemia", "Heart Failure", "Hemophilia", "Heavy Menstrual Bleeding", "Insomnia" ], "interventions": [ { "name": "The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daniel Benjamin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 3520, "start_date": "2011-11", "completion_date": "2019-11", "has_results": false, "last_update_posted_date": "2023-09-06", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 43, "location_summary": "Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more", "locations": [ { "city": "Anchorage", "state": "Alaska" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01431326" }, { "nct_id": "NCT02208063", "title": "A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bacteremia" ], "interventions": [ { "name": "Telavancin", "type": "DRUG" }, { "name": "Vancomycin", "type": "DRUG" }, { "name": "Daptomycin", "type": "DRUG" }, { "name": "Synthetic penicillin", "type": "DRUG" }, { "name": "Cefazolin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cumberland Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 121, "start_date": "2014-12", "completion_date": "2018-04-12", "has_results": true, "last_update_posted_date": "2020-02-17", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02208063" }, { "nct_id": "NCT00401960", "title": "Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Endocarditis, Bacterial" ], "interventions": [ { "name": "Daptomycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6, "start_date": "2006-09", "completion_date": "2008-10", "has_results": true, "last_update_posted_date": "2017-05-03", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00401960" }, { "nct_id": "NCT03138733", "title": "Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Staphylococcus Aureus Bacteremia" ], "interventions": [ { "name": "Ceftobiprole medocaril", "type": "DRUG" }, { "name": "Daptomycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Basilea Pharmaceutica", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 390, "start_date": "2018-08-26", "completion_date": "2022-03-11", "has_results": true, "last_update_posted_date": "2023-11-08", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 5, "location_summary": "Chula Vista, California • West Palm Beach, Florida • Butte, Montana + 2 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "West Palm Beach", "state": "Florida" }, { "city": "Butte", "state": "Montana" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03138733" }, { "nct_id": "NCT00995384", "title": "Cardiac Computed Tomography (CT) Scan Compared to Transesophageal Echocardiogram (TEE) in Endocarditis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Endocarditis" ], "interventions": [ { "name": "CT Scan", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Corewell Health East", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "98 Years", "sex": "ALL", "summary": "18 Years to 98 Years" }, "enrollment_count": 2, "start_date": "2009-10", "completion_date": "2010-10", "has_results": false, "last_update_posted_date": "2023-03-28", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 1, "location_summary": "Royal Oak, Michigan", "locations": [ { "city": "Royal Oak", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00995384" }, { "nct_id": "NCT04677114", "title": "Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Drug Use", "Opioid-use Disorder" ], "interventions": [ { "name": "Buprenorphine and Outpatient Parenteral Antibiotic Therapy", "type": "DRUG" }, { "name": "Buprenorphine and standard of care antibiotic treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Laura Fanucchi", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 71, "start_date": "2021-03-16", "completion_date": "2025-03-06", "has_results": true, "last_update_posted_date": "2026-04-28", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT04677114" }, { "nct_id": "NCT05329168", "title": "ERAdicate S. Aureus in Patients With Bacteremia and Endocarditis", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bacteremia Due to Staphylococcus Aureus", "Left Sided Infective Endocarditis (Disorder)", "Right Sided Infective Endocarditis (Disorder)", "Endocarditis Infective" ], "interventions": [ { "name": "Tonabacase (LSVT-1701)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Lysovant", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 0, "start_date": "2022-05-01", "completion_date": "2023-11-01", "has_results": false, "last_update_posted_date": "2022-06-30", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 1, "location_summary": "Butte, Montana", "locations": [ { "city": "Butte", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05329168" }, { "nct_id": "NCT00638157", "title": "Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Infective Endocarditis" ], "interventions": [ { "name": "daptomycin", "type": "DRUG" }, { "name": "daptomycin and gentamicin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2009-02-13", "completion_date": "2011-11-09", "has_results": true, "last_update_posted_date": "2021-02-02", "last_synced_at": "2026-05-21T22:17:54.806Z", "location_count": 4, "location_summary": "Denver, Colorado • Detroit, Michigan • Philadelphia, Pennsylvania", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00638157" } ] }