{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endocrine+Mechanisms", "query": { "condition": "Endocrine Mechanisms" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 95, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endocrine+Mechanisms&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T01:16:23.954Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01635062", "title": "The VALIDATE-D Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Type 2 Diabetes", "Obesity" ], "interventions": [ { "name": "Calcitriol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 41, "start_date": "2012-09", "completion_date": "2015-12", "has_results": true, "last_update_posted_date": "2017-04-11", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01635062" }, { "nct_id": "NCT05071287", "title": "Metabolism of Low Carbohydrate and Ketogenic Diet", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Diabetic Kidney Disease", "Cognitive Function", "Weight Loss", "Diabetic Control", "Type2 Diabetes" ], "interventions": [ { "name": "mHealth + low-fat diet", "type": "OTHER" }, { "name": "mHealth + low-carb/ketogenic diet", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2021-06-03", "completion_date": "2022-10-11", "has_results": false, "last_update_posted_date": "2025-02-21", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05071287" }, { "nct_id": "NCT01664624", "title": "Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Roflumilast", "type": "DRUG" }, { "name": "Alogliptin", "type": "DRUG" }, { "name": "Exenatide", "type": "DRUG" }, { "name": "Placebo to roflumilast", "type": "DRUG" }, { "name": "Placebo to alogliptin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2012-07", "completion_date": "2012-11", "has_results": true, "last_update_posted_date": "2017-02-01", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 2, "location_summary": "Chula Vista, California • Orlando, Florida", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01664624" }, { "nct_id": "NCT01911104", "title": "Exercise Resistance in Type 2 Diabetes", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Exercise", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "AdventHealth Translational Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "30 Years to 65 Years" }, "enrollment_count": 84, "start_date": "2013-10-31", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-03-30", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "Orlando, Florida", "locations": [ { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01911104" }, { "nct_id": "NCT00374907", "title": "A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Saxagliptin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Metformin (blinded)", "type": "DRUG" }, { "name": "Metformin (open-label)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 156, "start_date": "2006-09", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2015-05-07", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 3, "location_summary": "San Diego, California • Baton Rouge, Louisiana • San Antonio, Texas", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00374907" }, { "nct_id": "NCT01301105", "title": "The Effects of Mindfulness Training on Pain Regulation, Negative Affect, Attention, and Social Stress", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Focus on Pain Regulation Mechanisms", "Social Stress Mechanisms", "Basic Affective Mechanisms", "Attention Mechanisms", "Brain Mechanisms", "Immune Mechanisms", "Endocrine Mechanisms" ], "interventions": [ { "name": "Mindfulness Based Stress Reduction (MBSR)", "type": "BEHAVIORAL" }, { "name": "Health Enhancement Program (HEP)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 80, "start_date": "2005-10", "completion_date": "2007-04", "has_results": false, "last_update_posted_date": "2015-10-05", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01301105" }, { "nct_id": "NCT00018239", "title": "Aging and Cellular Mechanism for Insulin Action After Exercise Training", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Diabetes Mellitus" ], "interventions": [ { "name": "Exercise", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "US Department of Veterans Affairs", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "50 Years to 80 Years" }, "enrollment_count": null, "start_date": "1999-10", "completion_date": "2002-09", "has_results": false, "last_update_posted_date": "2009-01-21", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00018239" }, { "nct_id": "NCT06140537", "title": "Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Kidney Transplant; Complications", "Vascular Diseases", "Diabetes" ], "interventions": [ { "name": "Dapagliflozin 10mg Tab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 80, "start_date": "2024-02-01", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT06140537" }, { "nct_id": "NCT05013944", "title": "AnovaOS Network Powered Patient Registry", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Infectious Disease", "Neoplasms", "Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)", "Endocrine, Nutritional and Metabolic Diseases (E00-E89)", "Mental and Behavioural Disorders", "Diseases of the Nervous System", "Diseases of the Eye and Adnexa", "Diseases of the Ear and Mastoid Process", "Diseases of the Circulatory System", "Diseases of the Respiratory System", "Diseases of the Digestive System", "Diseases of the Skin and Subcutaneous Tissue", "Diseases of the Musculoskeletal System and Connective Tissue", "Diseases of the Genitourinary System", "Pregnancy, Childbirth and the Puerperium", "Certain Conditions Originating in the Perinatal Period", "Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99)", "Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified", "Injury, Poisoning and Certain Other Consequences of External Causes", "External Causes of Morbidity and Mortality", "Factors Influencing Health Status and Contact With Health Services" ], "interventions": [], "intervention_types": [], "sponsor": "Anova Enterprises, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100000, "start_date": "2021-09-01", "completion_date": "2026-08-31", "has_results": false, "last_update_posted_date": "2024-01-30", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "Arlington Heights, Illinois", "locations": [ { "city": "Arlington Heights", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05013944" }, { "nct_id": "NCT00816218", "title": "Molecular Mechanisms of Type 2 Diabetes Mellitus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Pioglitazone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 39, "start_date": "2003-03", "completion_date": "2008-11", "has_results": false, "last_update_posted_date": "2012-05-31", "last_synced_at": "2026-09-03T01:16:23.954Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00816218" } ] }