{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endodontic+Inflammation",
    "query": {
      "condition": "Endodontic Inflammation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endodontic+Inflammation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:36:57.919Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01622153",
      "title": "Electrical and Formocresol Pulpotomy in Primary Molars",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Reversible Pulpitis",
        "Caries"
      ],
      "interventions": [
        {
          "name": "Formocresol application after pulpotomy preparation",
          "type": "PROCEDURE"
        },
        {
          "name": "GENTLEray 980 Soft Tissue diode laser",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "3 Years to 8 Years"
      },
      "enrollment_count": 120,
      "start_date": "2011-06",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2017-05-10",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01622153"
    },
    {
      "nct_id": "NCT04385693",
      "title": "Intentional Pulpotomy to Preserve Hopeless Molars",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulpitis",
        "Dental Pulp Diseases",
        "Tooth Diseases"
      ],
      "interventions": [
        {
          "name": "Pulpotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Extraction and placement of space maintainer",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "5 Years to 10 Years"
      },
      "enrollment_count": 17,
      "start_date": "2020-06-12",
      "completion_date": "2023-04-12",
      "has_results": false,
      "last_update_posted_date": "2023-06-06",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04385693"
    },
    {
      "nct_id": "NCT06047366",
      "title": "Combination of Buffered Anesthetic to Treat Mandibular Molars",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Symptomatic Irreversible Pulpitis"
      ],
      "interventions": [
        {
          "name": "Sodium bicarbonate",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine w/ epi",
          "type": "DRUG"
        },
        {
          "name": "Articaine w/ epi",
          "type": "DRUG"
        },
        {
          "name": "Mepivacaine plain",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-12-05",
      "completion_date": "2024-05-15",
      "has_results": true,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06047366"
    },
    {
      "nct_id": "NCT01060774",
      "title": "Bupivacaine Versus Lidocaine on Inflammatory Regulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Maryland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 11,
      "start_date": "2008-07",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2018-05-31",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01060774"
    },
    {
      "nct_id": "NCT06843525",
      "title": "Bite Force Measurements",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Irreversible Pulpitis",
        "Apical Periodontitis",
        "Pulpal Necrosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 112,
      "start_date": "2025-05-16",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06843525"
    },
    {
      "nct_id": "NCT04922229",
      "title": "Comparative Effectiveness in the Management of Irreversible Pulpitis",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Irreversible Pulpitis"
      ],
      "interventions": [
        {
          "name": "RCT",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulpotomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "12 Years to 99 Years"
      },
      "enrollment_count": 138,
      "start_date": "2027-06-01",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04922229"
    },
    {
      "nct_id": "NCT02635867",
      "title": "Clinical Comparison of Vital Pulp Capping Restorative Protocols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Deep Dental Caries"
      ],
      "interventions": [
        {
          "name": "Indirect Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Resin-based dentin bonding agent",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 109,
      "start_date": "2015-06",
      "completion_date": "2019-08",
      "has_results": true,
      "last_update_posted_date": "2023-10-12",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02635867"
    },
    {
      "nct_id": "NCT04552132",
      "title": "Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Irreversible Pulpitis",
        "Apical Periodontitis"
      ],
      "interventions": [
        {
          "name": "Multisonic vs Sonic activation of irrigants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2020-09-30",
      "completion_date": "2022-03-16",
      "has_results": true,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04552132"
    },
    {
      "nct_id": "NCT00001952",
      "title": "Using a Narcotic to Enhance the Numbing Effect of the Local Anesthetic Lidocaine on Inflamed Molar Teeth",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy",
        "Inflammation",
        "Mouth Disease",
        "Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 275,
      "start_date": "1999-11",
      "completion_date": "2002-12",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001952"
    },
    {
      "nct_id": "NCT04157036",
      "title": "Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Irreversible Pulpitis"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Methylprednisolone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2020-02-01",
      "completion_date": "2021-10-06",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-05-22T07:36:57.919Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04157036"
    }
  ]
}