{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endotracheal+Extubation&page=2",
    "query": {
      "condition": "Endotracheal Extubation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Endotracheal+Extubation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:08:33.159Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04258020",
      "title": "Postextubation Management in Patients at Risk for Extubation Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventilatory Failure"
      ],
      "interventions": [
        {
          "name": "BiPAP",
          "type": "DEVICE"
        },
        {
          "name": "HFNC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2020-02-11",
      "completion_date": "2020-04-02",
      "has_results": true,
      "last_update_posted_date": "2022-01-13",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04258020"
    },
    {
      "nct_id": "NCT04971148",
      "title": "Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxemic Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "HFNC flow set at patient peak tidal inspiratory flow",
          "type": "OTHER"
        },
        {
          "name": "HFNC flow set at 1.33 times of patient peak tidal inspiratory flow",
          "type": "OTHER"
        },
        {
          "name": "HFNC flow set at 1.67 times of patient peak tidal inspiratory flow",
          "type": "OTHER"
        },
        {
          "name": "HFNC flow set at 2 times of patient peak tidal inspiratory flow",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 5,
      "start_date": "2022-04-07",
      "completion_date": "2023-08-08",
      "has_results": false,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04971148"
    },
    {
      "nct_id": "NCT01095276",
      "title": "Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atelectasis",
        "Ventilation, Mechanical"
      ],
      "interventions": [
        {
          "name": "Pulmozyme (nebulized dornase alpha)",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2005-11",
      "completion_date": "2006-01",
      "has_results": false,
      "last_update_posted_date": "2010-03-30",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01095276"
    },
    {
      "nct_id": "NCT07204990",
      "title": "BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endotracheal Extubation",
        "Airway Anesthesia",
        "Paediatric"
      ],
      "interventions": [
        {
          "name": "Direct removal of endotracheal tube",
          "type": "PROCEDURE"
        },
        {
          "name": "Laryngeal mask airway inserted following deep extubation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Telethon Kids Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "0 Years to 16 Years"
      },
      "enrollment_count": 1400,
      "start_date": "2026-02-06",
      "completion_date": "2029-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 2,
      "location_summary": "Winston-Salem, North Carolina • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07204990"
    },
    {
      "nct_id": "NCT01237886",
      "title": "Weaning And Variability Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mechanically Ventilated Patients",
        "Extubation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ottawa Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 660,
      "start_date": "2009-11",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2017-07-07",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 7,
      "location_summary": "Ann Arbor, Michigan • Billings, Montana • Lebanon, New Hampshire + 4 more",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Billings",
          "state": "Montana"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01237886"
    },
    {
      "nct_id": "NCT04349332",
      "title": "Early Extubation for Patients With Acute Hypoxemic Respiratory Failure",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mechanical Ventilation",
        "Corona Virus Infection"
      ],
      "interventions": [
        {
          "name": "Helmet non-invasive ventilation (NIV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-08-13",
      "completion_date": "2024-01-09",
      "has_results": false,
      "last_update_posted_date": "2024-05-02",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04349332"
    },
    {
      "nct_id": "NCT06990308",
      "title": "Deflated and Inflated Cuff Endotracheal Extubations",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia Airway Management",
        "Respiratory Complications"
      ],
      "interventions": [
        {
          "name": "Inflated Cuff Extubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Deflated Cuff Extubation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Naval Medical Center Camp Lejeune",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 88,
      "start_date": "2025-06-17",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2025-12-16",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Marine Corps Base Camp Lejeune, North Carolina",
      "locations": [
        {
          "city": "Marine Corps Base Camp Lejeune",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06990308"
    },
    {
      "nct_id": "NCT04052542",
      "title": "METEOR Think NIV Pilot",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Traditional online continuing education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Interprofessional education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Just-in-time education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1328,
      "start_date": "2019-08-28",
      "completion_date": "2019-11-20",
      "has_results": true,
      "last_update_posted_date": "2021-10-06",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04052542"
    },
    {
      "nct_id": "NCT04759066",
      "title": "The HEALiX™ Intubated Patient (IP) Pilot Study",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Device Ineffective",
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "HEALiX",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lancaster General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-10-01",
      "completion_date": "2022-06-01",
      "has_results": false,
      "last_update_posted_date": "2022-01-03",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Lancaster, Pennsylvania",
      "locations": [
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04759066"
    },
    {
      "nct_id": "NCT00563238",
      "title": "Beta-blocker Before Extubation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myocardial Ischemia"
      ],
      "interventions": [
        {
          "name": "Metoprolol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gregory A. Schmidt",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 0,
      "start_date": "2007-11",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2017-02-28",
      "last_synced_at": "2026-06-11T04:08:33.159Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00563238"
    }
  ]
}