{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Esophageal+Diseases&page=2", "query": { "condition": "Esophageal Diseases", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Esophageal+Diseases&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T04:16:20.548Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01351103", "title": "A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Pancreatic Cancer", "BRAF Mutant Colorectal Cancer", "Melanoma", "Triple Negative Breast Cancer", "Head and Neck Squamous Cell Cancer", "Cervical Squamous Cell Cancer", "Esophageal Squamous Cell Cancer", "Lung Squamous Cell Cancer" ], "interventions": [ { "name": "LGK974", "type": "DRUG" }, { "name": "PDR001", "type": "BIOLOGICAL" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 185, "start_date": "2011-12-01", "completion_date": "2024-06-17", "has_results": false, "last_update_posted_date": "2025-06-13", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 6, "location_summary": "Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 3 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01351103" }, { "nct_id": "NCT04926077", "title": "DreamKit Respiratory Effort Signal Validation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sleep Apnea, Obstructive", "Sleep Apnea, Central" ], "interventions": [ { "name": "DreamKit", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Philips Clinical & Medical Affairs Global", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2021-06-22", "completion_date": "2021-10-07", "has_results": true, "last_update_posted_date": "2022-11-30", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04926077" }, { "nct_id": "NCT00579410", "title": "Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Esophagitis", "Inflammation", "Gastritis", "Abdominal Pain", "Heartburn" ], "interventions": [], "intervention_types": [], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 85, "start_date": "2004-05", "completion_date": "2009-10", "has_results": false, "last_update_posted_date": "2011-03-22", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00579410" }, { "nct_id": "NCT02504853", "title": "Natural History and Genetics of Food Allergy and Related Conditions", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Food Allergy", "Loeys-Dietz Syndrome", "Atopic Dermatitis", "Eosinophilic Esophagitis" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "1 Day", "maximum_age": "99 Years", "sex": "ALL", "summary": "1 Day to 99 Years" }, "enrollment_count": 1800, "start_date": "2015-07-29", "completion_date": "2026-06-15", "has_results": false, "last_update_posted_date": "2026-05-20", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02504853" }, { "nct_id": "NCT06695845", "title": "A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Breast Cancer", "Gastric Cancer", "Esophageal Cancer", "Gastroesophageal Cancer", "Colorectal Cancer", "Endometrial Cancer", "Non-small Cell Lung Cancer", "Ovarian Cancer", "Urothelial Carcinoma", "Salivary Gland Cancer", "Pancreatic Cancer", "HER-2 Protein Overexpression" ], "interventions": [ { "name": "Zanidatamab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jazz Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2025-01-14", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-04-09", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 16, "location_summary": "Prescott, Arizona • Littleton, Colorado • Fort Myers, Florida + 13 more", "locations": [ { "city": "Prescott", "state": "Arizona" }, { "city": "Littleton", "state": "Colorado" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06695845" }, { "nct_id": "NCT05187182", "title": "CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Gastric Cancer", "Esophageal Cancer", "Stomach Cancer", "Esophagus Cancer", "Gastroesophageal Junction Cancer" ], "interventions": [ { "name": "CA-4948", "type": "DRUG" }, { "name": "Nivolumab", "type": "BIOLOGICAL" }, { "name": "Pembrolizumab", "type": "BIOLOGICAL" }, { "name": "Trastuzumab", "type": "DRUG" }, { "name": "mFOLFOX7", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 42, "start_date": "2023-06-02", "completion_date": "2029-04-30", "has_results": false, "last_update_posted_date": "2026-04-27", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05187182" }, { "nct_id": "NCT00393653", "title": "Prescription Methods Assessment Project (PMAP)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Osteoarthritis", "Gastroesophageal Reflux Disease" ], "interventions": [ { "name": "N-of-1 prescription method", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "American Academy of Family Physicians", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 800, "start_date": "2006-10", "completion_date": "2007-05", "has_results": false, "last_update_posted_date": "2011-05-10", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Leawood, Kansas", "locations": [ { "city": "Leawood", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00393653" }, { "nct_id": "NCT06352073", "title": "Dupilumab for Eosinophilic Esophagitis With Severe Strictures", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Eosinophilic Esophagitis", "EoE" ], "interventions": [ { "name": "Dupilumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 23, "start_date": "2024-05-16", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-04-29", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06352073" }, { "nct_id": "NCT06381583", "title": "A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Esophagus Cancer", "Esophageal Cancer Stage", "Esophageal Cancer", "Esophageal Neoplasms", "Esophagus Adenocarcinoma", "Esophagus, Barrett", "Barrett Esophagus", "Barrett Adenocarcinoma", "Barrett Epithelium", "Barretts Esophagus With Dysplasia", "Barrett's Esophagus Without Dysplasia", "Barretts Esophagus With High Grade Dysplasia", "Barretts Esophagus With Low Grade Dysplasia", "Barrett Esophagus, Long-Segment", "Barrett's Esophagus With Dysplasia, Unspecified", "Barrett's Esophagus With Esophagitis", "Gastroesophageal Reflux", "Reflux Disease", "Esophageal Adenocarcinoma", "Esophageal Dysplasia", "Esophageal Neoplasms Malignant" ], "interventions": [ { "name": "EMERALD (Esophageal MicroRNAs for BaRRett's esophagus, Adenocarcinoma, and Dysplasia)", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 658, "start_date": "2023-04-15", "completion_date": "2024-04-24", "has_results": false, "last_update_posted_date": "2024-05-10", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06381583" }, { "nct_id": "NCT00674245", "title": "Effect of Pantoprazole 40mg Daily vs Placebo on Power Spectral Analysis of the Sleep EEG of Patients With GERD.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Gastroesophageal Reflux Disease" ], "interventions": [ { "name": "Pantoprazole", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Southern Arizona VA Health Care System", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2008-04", "completion_date": "2010-07", "has_results": false, "last_update_posted_date": "2010-08-19", "last_synced_at": "2026-05-22T04:16:20.548Z", "location_count": 1, "location_summary": "Tucson, Arizona", "locations": [ { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00674245" } ] }