{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Estrogens&page=26", "query": { "condition": "Estrogens", "page": 26 }, "page_size": 10 }, "pagination": { "page": 26, "page_size": 10, "total_count": 754, "total_pages": 76, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Estrogens&page=27&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Estrogens&page=25&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-02T23:32:50.517Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03240081", "title": "Treating Postmenopausal Dyspareunia Where it Hurts", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Dyspareunia" ], "interventions": [ { "name": "50mcg estradiol cream", "type": "DRUG" }, { "name": "100mcg estradiol cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Oregon Health and Science University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "70 Years", "sex": "FEMALE", "summary": "40 Years to 70 Years · Female only" }, "enrollment_count": 50, "start_date": "2017-06-20", "completion_date": "2019-11-21", "has_results": true, "last_update_posted_date": "2023-05-22", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT03240081" }, { "nct_id": "NCT01805076", "title": "MRI and Mammography Before Surgery in Patients With Stage I-II Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Estrogen Receptor-negative Breast Cancer", "Progesterone Receptor-negative Breast Cancer", "Stage IA Breast Cancer", "Stage IB Breast Cancer", "Stage II Breast Cancer", "Triple-negative Breast Cancer" ], "interventions": [ { "name": "Breast surgery", "type": "PROCEDURE" }, { "name": "Magnetic resonance imaging", "type": "PROCEDURE" }, { "name": "Mammography", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 319, "start_date": "2014-05-21", "completion_date": "2025-05-27", "has_results": true, "last_update_posted_date": "2026-06-26", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 179, "location_summary": "Gilbert, Arizona • Jonesboro, Arkansas • Antioch, California + 141 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Antioch", "state": "California" }, { "city": "Chico", "state": "California" }, { "city": "Emeryville", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01805076" }, { "nct_id": "NCT01208324", "title": "Estrogen and Serotonin on Changing Brain Chemistry", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Menopause" ], "interventions": [ { "name": "estrogen patch", "type": "DRUG" }, { "name": "Amino acids", "type": "DRUG" }, { "name": "Placebo Patch", "type": "DRUG" }, { "name": "Placebo pills", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "48 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "48 Years to 60 Years · Female only" }, "enrollment_count": 47, "start_date": "2010-03-04", "completion_date": "2018-11", "has_results": true, "last_update_posted_date": "2021-04-02", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01208324" }, { "nct_id": "NCT00455962", "title": "Effect of Race on Gonadotropin Responses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Premenopause", "Healthy" ], "interventions": [ { "name": "Estradiol steroid infusion", "type": "DRUG" }, { "name": "Progesterone steroid infusion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "FEMALE", "summary": "18 Years to 35 Years · Female only" }, "enrollment_count": 23, "start_date": "2005-01", "completion_date": "2011-12", "has_results": true, "last_update_posted_date": "2017-07-27", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00455962" }, { "nct_id": "NCT00066690", "title": "Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Estrogen Receptor Positive Breast Cancer", "Progesterone Receptor Positive Tumor", "Recurrent Breast Carcinoma", "Stage IA Breast Cancer", "Stage IB Breast Cancer", "Stage IIA Breast Cancer", "Stage IIB Breast Cancer", "Stage IIIA Breast Cancer" ], "interventions": [ { "name": "Exemestane", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Oophorectomy", "type": "PROCEDURE" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "Tamoxifen", "type": "DRUG" }, { "name": "Triptorelin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE", "RADIATION" ], "sponsor": "ETOP IBCSG Partners Foundation", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "18 Years to 65 Years · Female only" }, "enrollment_count": 3066, "start_date": "2003-12-17", "completion_date": "2024-11-06", "has_results": true, "last_update_posted_date": "2026-08-26", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 480, "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Scottsdale, Arizona + 323 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Berkeley", "state": "California" }, { "city": "Burlingame", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00066690" }, { "nct_id": "NCT00196378", "title": "A Clinical Trial to Evaluate the Safety and Efficacy of Enjuvia 0.3 mg for the Treatment of Vulvovaginal Atrophy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Menopause" ], "interventions": [ { "name": "Synthetic Conjugated estrogens, B", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Duramed Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "80 Years", "sex": "FEMALE", "summary": "30 Years to 80 Years · Female only" }, "enrollment_count": 300, "start_date": "2004-11", "completion_date": "2006-02", "has_results": false, "last_update_posted_date": "2013-09-02", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 38, "location_summary": "Huntsville, Alabama • Tucson, Arizona • Carmichael, California + 31 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Carmichael", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00196378" }, { "nct_id": "NCT00000897", "title": "A Study to Evaluate the Effects of Different Methods of Birth Control on the Drug Actions of Zidovudine (an Anti-HIV Drug) in HIV-Positive Women and to Compare Zidovudine Metabolism in Men and Women", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Zidovudine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 42, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2011-03-02", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 6, "location_summary": "San Francisco, California • Jacksonville, Florida • Albany, New York + 3 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Albany", "state": "New York" }, { "city": "Buffalo", "state": "New York" }, { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000897" }, { "nct_id": "NCT06353269", "title": "Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Recurrent Urinary Tract Infection", "Hypoestrogenism" ], "interventions": [ { "name": "Estring Vaginal Product", "type": "DRUG" }, { "name": "Vagifem", "type": "DRUG" }, { "name": "Estrace 0.01% Vaginal Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Irvine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 111, "start_date": "2024-06-14", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2026-06-11", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 1, "location_summary": "Orange, California", "locations": [ { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06353269" }, { "nct_id": "NCT01547741", "title": "Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Docetaxel", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NSABP Foundation Inc", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 4242, "start_date": "2012-04", "completion_date": "2025-10-17", "has_results": true, "last_update_posted_date": "2026-08-06", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 914, "location_summary": "Anchorage, Alaska • Phoenix, Arizona • Scottsdale, Arizona + 612 more", "locations": [ { "city": "Anchorage", "state": "Alaska" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Sedona", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01547741" }, { "nct_id": "NCT03815929", "title": "Oophorectomy, Estrogen Therapy and Cardiovascular Disease Risk in Young Women", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cardiovascular Risk Reduction" ], "interventions": [ { "name": "Estradiol 100 Micrograms Patch", "type": "DRUG" }, { "name": "Estradiol Patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "21 Years to 45 Years · Female only" }, "enrollment_count": 35, "start_date": "2019-03-15", "completion_date": "2023-08-28", "has_results": true, "last_update_posted_date": "2024-10-23", "last_synced_at": "2026-11-02T23:32:50.517Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03815929" } ] }