{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eustachian+Tube+Dysfunction",
    "query": {
      "condition": "Eustachian Tube Dysfunction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eustachian+Tube+Dysfunction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:31:06.069Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04804098",
      "title": "Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ear Barotrauma",
        "Middle Ear Disease",
        "Ear Diseases",
        "Pressure Injury",
        "Eustachian Tube Dysfunction",
        "Middle Ear; Injury",
        "Middle Ear Barotrauma"
      ],
      "interventions": [
        {
          "name": "Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)",
          "type": "PROCEDURE"
        },
        {
          "name": "Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 300,
      "start_date": "2021-09-20",
      "completion_date": "2024-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-19",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 1,
      "location_summary": "Sleepy Hollow, New York",
      "locations": [
        {
          "city": "Sleepy Hollow",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04804098"
    },
    {
      "nct_id": "NCT02087150",
      "title": "Study of Safety and Efficacy for the Eustachian Tube Balloon Catheter",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eustachian Tube Dysfunction"
      ],
      "interventions": [
        {
          "name": "Acclarent Eustachian Tube Balloon Catheter (ETBC)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 323,
      "start_date": "2014-02-01",
      "completion_date": "2017-01-12",
      "has_results": true,
      "last_update_posted_date": "2024-07-12",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 21,
      "location_summary": "East Palo Alto, California • Washington D.C., District of Columbia • Boca Raton, Florida + 17 more",
      "locations": [
        {
          "city": "East Palo Alto",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        },
        {
          "city": "Boynton Beach",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02087150"
    },
    {
      "nct_id": "NCT01312038",
      "title": "Effect of Simethicone on Eustachian Tube Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Otitis Media"
      ],
      "interventions": [
        {
          "name": "Simethicone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 25,
      "start_date": "2011-03",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2016-06-27",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01312038"
    },
    {
      "nct_id": "NCT04776967",
      "title": "Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eustachian Tube Dysfunction",
        "Middle Ear Barotrauma",
        "Middle Ear Disease",
        "Middle Ear; Injury",
        "Pressure Injury",
        "Ear Barotrauma"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Compression Profile",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 300,
      "start_date": "2014-09-08",
      "completion_date": "2021-02-28",
      "has_results": false,
      "last_update_posted_date": "2021-08-19",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 1,
      "location_summary": "Sleepy Hollow, New York",
      "locations": [
        {
          "city": "Sleepy Hollow",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04776967"
    },
    {
      "nct_id": "NCT01251432",
      "title": "Risk Factors and Potential Causes of Eustachian Tube Dysfunction in Adults",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eustachian Tube Dysfunction",
        "Chronic Otitis Media"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2010-06",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-11-04",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01251432"
    },
    {
      "nct_id": "NCT00279916",
      "title": "Short Term Relief of Eustachian Tube Dysfunction and Serous Otitis Media Using Intranasal Steroid Sprays",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Otitis Media, Serous",
        "Negative Middle Ear Pressure",
        "Rhinitis",
        "Otitis Media With Effusion",
        "Otitis Media, Secretory"
      ],
      "interventions": [
        {
          "name": "Triamcinolone acetonide nasal spray",
          "type": "DRUG"
        },
        {
          "name": "Placebo nasal spray",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "6 Years to 100 Years"
      },
      "enrollment_count": 91,
      "start_date": "2005-09-01",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00279916"
    },
    {
      "nct_id": "NCT02391584",
      "title": "XprESS Eustachian Tube Dilation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eustachian Tube Dysfunction"
      ],
      "interventions": [
        {
          "name": "XprESS",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Entellus Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2015-02",
      "completion_date": "2017-10",
      "has_results": true,
      "last_update_posted_date": "2018-11-01",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 5,
      "location_summary": "Denver, Colorado • North Platte, Nebraska • Sayre, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "North Platte",
          "state": "Nebraska"
        },
        {
          "city": "Sayre",
          "state": "Pennsylvania"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02391584"
    },
    {
      "nct_id": "NCT02123498",
      "title": "The Study of Eustachian Tube Dysfunction and Laryngopharyngeal Reflux",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Eustachian Tube Dysfunction",
        "Laryngopharyngeal Reflux"
      ],
      "interventions": [
        {
          "name": "Omeprazole",
          "type": "DRUG"
        },
        {
          "name": "Ranitidine",
          "type": "DRUG"
        },
        {
          "name": "Pantoprazole",
          "type": "DRUG"
        },
        {
          "name": "24-Hour Diagnostic pH-Probe Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Laryngoscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-09-26",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 2,
      "location_summary": "Loma Linda, California • Redlands, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Redlands",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02123498"
    },
    {
      "nct_id": "NCT01974726",
      "title": "Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eustachian Tube Dysfunction"
      ],
      "interventions": [
        {
          "name": "ET Stress test",
          "type": "OTHER"
        },
        {
          "name": "Sonotubometry",
          "type": "OTHER"
        },
        {
          "name": "Forced Response Test (FRT)",
          "type": "OTHER"
        },
        {
          "name": "Inflation Deflation Test (IDT)",
          "type": "OTHER"
        },
        {
          "name": "Maneuver Sequence",
          "type": "OTHER"
        },
        {
          "name": "9-Step Test",
          "type": "OTHER"
        },
        {
          "name": "Tubomanometry",
          "type": "OTHER"
        },
        {
          "name": "Videoendoscopic assessment of ETF",
          "type": "OTHER"
        },
        {
          "name": "Pressure chamber ET test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "3 Years to 70 Years"
      },
      "enrollment_count": 95,
      "start_date": "2013-10",
      "completion_date": "2019-06-27",
      "has_results": false,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01974726"
    },
    {
      "nct_id": "NCT03197558",
      "title": "Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Barotrauma;Ear",
        "OME - Otitis Media With Effusion",
        "AOM - Acute Otitis Media",
        "Eustachian Tube Dysfunction"
      ],
      "interventions": [
        {
          "name": "Tymbion Iontophoresis and Tube Delivery System (TDS)",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Tusker Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-06-27",
      "completion_date": "2017-09-14",
      "has_results": true,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-05-22T07:31:06.069Z",
      "location_count": 8,
      "location_summary": "Roseville, California • San Jose, California • Louisville, Kentucky + 5 more",
      "locations": [
        {
          "city": "Roseville",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03197558"
    }
  ]
}