{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extreme+Immaturity&page=2",
    "query": {
      "condition": "Extreme Immaturity",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extreme+Immaturity&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T19:36:49.810Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00455169",
      "title": "Influenza Vaccine in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Influenza",
        "Infant, Premature"
      ],
      "interventions": [
        {
          "name": "Trivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "17 Months",
        "sex": "ALL",
        "summary": "6 Months to 17 Months"
      },
      "enrollment_count": 66,
      "start_date": "2007-10",
      "completion_date": "2008-05",
      "has_results": false,
      "last_update_posted_date": "2015-09-17",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 5,
      "location_summary": "Miami, Florida • Buffalo, New York • Rochester, New York + 2 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00455169"
    },
    {
      "nct_id": "NCT06399861",
      "title": "Humidity in Incubators for Tiny Infants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Extremely Premature Infant"
      ],
      "interventions": [
        {
          "name": "Incubator ambient relative humidity (RH) of 70%",
          "type": "DEVICE"
        },
        {
          "name": "Incubator ambient relative humidity (RH) of 90%",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "1 Day",
        "sex": "ALL",
        "summary": "0 Days to 1 Day"
      },
      "enrollment_count": 350,
      "start_date": "2024-06-25",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-29",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 6,
      "location_summary": "Columbus, Ohio • Houston, Texas • San Antonio, Texas",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06399861"
    },
    {
      "nct_id": "NCT02915549",
      "title": "Early Progressive Feeding in Human-Milk Fed Extremely Preterm Infants: A Randomized Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature; Infant, Light-for-dates"
      ],
      "interventions": [
        {
          "name": "Progressive Feeding without MEF",
          "type": "OTHER"
        },
        {
          "name": "Progressive Feeding with MEF",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Hours",
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "24 Hours to 48 Hours"
      },
      "enrollment_count": 60,
      "start_date": "2016-09",
      "completion_date": "2022-11",
      "has_results": false,
      "last_update_posted_date": "2022-12-16",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02915549"
    },
    {
      "nct_id": "NCT00005775",
      "title": "Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Glutamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 1433,
      "start_date": "1999-07",
      "completion_date": "2001-08",
      "has_results": false,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005775"
    },
    {
      "nct_id": "NCT07307612",
      "title": "High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Extreme Prematurity",
        "Enteral Nutrition",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "High-energy group",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Standard-energy group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "3 Days",
        "sex": "ALL",
        "summary": "1 Day to 3 Days"
      },
      "enrollment_count": 150,
      "start_date": "2026-08-15",
      "completion_date": "2029-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07307612"
    },
    {
      "nct_id": "NCT05011149",
      "title": "Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Patent Ductus Arteriosus After Premature Birth"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "IWK Health Centre",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 100,
      "start_date": "2022-01-10",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 3,
      "location_summary": "Orange, California • San Diego, California • Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05011149"
    },
    {
      "nct_id": "NCT04715373",
      "title": "LISA in the Delivery Room for Extremely Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Extreme Prematurity",
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "LISA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Minutes",
        "maximum_age": "20 Minutes",
        "sex": "ALL",
        "summary": "5 Minutes to 20 Minutes"
      },
      "enrollment_count": 60,
      "start_date": "2021-06-22",
      "completion_date": "2025-04-08",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04715373"
    },
    {
      "nct_id": "NCT01795638",
      "title": "Sodium Supplementation and Growth in Very Low Birth Weight Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Extreme Immaturity"
      ],
      "interventions": [
        {
          "name": "Sodium chloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "8 Days",
        "sex": "ALL",
        "summary": "7 Days to 8 Days"
      },
      "enrollment_count": 53,
      "start_date": "2009-10",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2020-09-07",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01795638"
    },
    {
      "nct_id": "NCT03695900",
      "title": "Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apnea of Prematurity",
        "Desaturation of Blood",
        "Central Apnea",
        "Periodic Breathing",
        "Obstructive Apnea of Newborn"
      ],
      "interventions": [
        {
          "name": "Targeting SpO2 at 93-95%",
          "type": "OTHER"
        },
        {
          "name": "Targeting SpO2 at 90-92%",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Weeks",
        "sex": "ALL",
        "summary": "Up to 18 Weeks"
      },
      "enrollment_count": 19,
      "start_date": "2018-11-01",
      "completion_date": "2019-11-08",
      "has_results": false,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03695900"
    },
    {
      "nct_id": "NCT00156559",
      "title": "MMR and Varicella Vaccine in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chickenpox",
        "Rubella",
        "Rubeola",
        "Mumps"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "16 Months",
        "sex": "ALL",
        "summary": "12 Months to 16 Months"
      },
      "enrollment_count": 32,
      "start_date": "2004-01",
      "completion_date": "2005-05",
      "has_results": false,
      "last_update_posted_date": "2015-09-17",
      "last_synced_at": "2026-07-22T19:36:49.810Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00156559"
    }
  ]
}