{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extreme+Prematurity&page=2",
    "query": {
      "condition": "Extreme Prematurity",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extreme+Prematurity&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:45:46.769Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06915441",
      "title": "Lipid Infusions to Optimize Nutrition Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Neurodevelopmental Impairment"
      ],
      "interventions": [
        {
          "name": "SOLE",
          "type": "DRUG"
        },
        {
          "name": "MOLE",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Hours",
        "maximum_age": "28 Weeks",
        "sex": "ALL",
        "summary": "12 Hours to 28 Weeks"
      },
      "enrollment_count": 230,
      "start_date": "2026-05-01",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06915441"
    },
    {
      "nct_id": "NCT04294368",
      "title": "Targeted Fortification of Donor Breast Milk in Preterm Infants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity; Extreme",
        "Failure to Thrive in Newborn",
        "Growth Retardation",
        "Growth Failure",
        "Infant Nutrition Disorders"
      ],
      "interventions": [
        {
          "name": "Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Liquid Protein Fortifier",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Nestle Microlipid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Medica Nutrition SolCarb",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Liquid Protein Fortifier (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Nestle Microlipid (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Medica Nutrition SolCarb (Targeted Fortification)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Analysis with Miris (AB) Human Milk Analyzer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "1 Day to 21 Days"
      },
      "enrollment_count": 50,
      "start_date": "2020-03-09",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04294368"
    },
    {
      "nct_id": "NCT04584983",
      "title": "Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bilirubin Encephalopathy"
      ],
      "interventions": [
        {
          "name": "usual prescribed intralipid (UL) regimen",
          "type": "DRUG"
        },
        {
          "name": "restricted prescribed intralipid (RL) regimen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "27 Weeks",
        "sex": "ALL",
        "summary": "Up to 27 Weeks"
      },
      "enrollment_count": 134,
      "start_date": "2021-02-11",
      "completion_date": "2026-06-14",
      "has_results": true,
      "last_update_posted_date": "2025-11-28",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04584983"
    },
    {
      "nct_id": "NCT00874367",
      "title": "Early-Onset Sepsis Surveillance Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Sepsis",
        "Gram-Negative Bacterial Infections",
        "Gram-Positive Bacterial Infections"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 615,
      "start_date": "2006-02",
      "completion_date": "2011-05",
      "has_results": false,
      "last_update_posted_date": "2017-09-25",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00874367"
    },
    {
      "nct_id": "NCT02943746",
      "title": "Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Infants"
      ],
      "interventions": [
        {
          "name": "Standard Protein Diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High Protein Diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Days and older"
      },
      "enrollment_count": 118,
      "start_date": "2016-11",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02943746"
    },
    {
      "nct_id": "NCT02742454",
      "title": "VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraventricular Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Standard 30-60 Seconds Cord Clamping",
          "type": "PROCEDURE"
        },
        {
          "name": "VentFirst 120 Seconds Cord Clamping",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 570,
      "start_date": "2016-06",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Sacramento, California • Denver, Colorado + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02742454"
    },
    {
      "nct_id": "NCT00156559",
      "title": "MMR and Varicella Vaccine in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chickenpox",
        "Rubella",
        "Rubeola",
        "Mumps"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "16 Months",
        "sex": "ALL",
        "summary": "12 Months to 16 Months"
      },
      "enrollment_count": 32,
      "start_date": "2004-01",
      "completion_date": "2005-05",
      "has_results": false,
      "last_update_posted_date": "2015-09-17",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00156559"
    },
    {
      "nct_id": "NCT00011362",
      "title": "Dexamethasone Therapy in VLBW Infants at Risk of CLD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Dexamethasone Early",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone Late",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Days",
        "maximum_age": "15 Days",
        "sex": "ALL",
        "summary": "13 Days to 15 Days"
      },
      "enrollment_count": 371,
      "start_date": "1992-09",
      "completion_date": "1994-04",
      "has_results": false,
      "last_update_posted_date": "2019-03-22",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 13,
      "location_summary": "Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00011362"
    },
    {
      "nct_id": "NCT02016599",
      "title": "Effects of Transitional Circulation in ELBW Infants",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Prematurity",
        "Hypotension"
      ],
      "interventions": [
        {
          "name": "Monitoring and biospecimen collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Week",
        "sex": "ALL",
        "summary": "Up to 1 Week"
      },
      "enrollment_count": 200,
      "start_date": "2017-09-22",
      "completion_date": "2032-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02016599"
    },
    {
      "nct_id": "NCT01758913",
      "title": "Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Taipei Medical University Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 110,
      "start_date": "2007-02",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2013-01-03",
      "last_synced_at": "2026-06-11T04:45:46.769Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01758913"
    }
  ]
}