{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Fracture+Lower",
    "query": {
      "condition": "Extremity Fracture Lower"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 41,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Fracture+Lower&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:21:45.043Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05927480",
      "title": "Audio Distraction for Traction Pin Placement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity Fracture"
      ],
      "interventions": [
        {
          "name": "Audio distraction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "HealthPartners Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2018-04-25",
      "completion_date": "2022-12-31",
      "has_results": true,
      "last_update_posted_date": "2024-12-03",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05927480"
    },
    {
      "nct_id": "NCT07552766",
      "title": "A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fracture Arm",
        "Fracture Closed of Lower End of Forearm, Unspecified",
        "Fracture Elbow",
        "Fracture Fixation",
        "Fracture Fixation, Internal",
        "Fracture Forearm",
        "Fracture Distal Radius"
      ],
      "interventions": [
        {
          "name": "Lidocaine Infusion",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care (SOC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Years to 18 Years"
      },
      "enrollment_count": 90,
      "start_date": "2026-05",
      "completion_date": "2029-07",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07552766"
    },
    {
      "nct_id": "NCT01550094",
      "title": "A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Strain of Muscle and/or Tendon of Lower Leg",
        "Fracture of Lower Leg",
        "Crushing Injury of Lower Leg",
        "Fracture Malunion - Ankle and/ or Foot",
        "Complete Tear, Ankle and/or Foot Ligament",
        "Pathological Fracture - Ankle and/or Foot",
        "Loose Body in Joint of Ankle and/or Foot"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Jose Soberon, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2012-03",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2015-10-14",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01550094"
    },
    {
      "nct_id": "NCT06293469",
      "title": "Accelerated Flap Coverage in Severe Lower Extremity Trauma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Open Tibia Fracture",
        "Open Dislocation of Ankle",
        "Extremity Fracture Lower",
        "Extremity Injuries Lower"
      ],
      "interventions": [
        {
          "name": "Accelerated Flap Coverage Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care Flap Timing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 356,
      "start_date": "2024-11-04",
      "completion_date": "2030-02",
      "has_results": false,
      "last_update_posted_date": "2025-10-14",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 7,
      "location_summary": "Sacramento, California • Baltimore, Maryland • Largo, Maryland + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Largo",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06293469"
    },
    {
      "nct_id": "NCT01167907",
      "title": "Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthopedic Surgery of Lower Extremity"
      ],
      "interventions": [
        {
          "name": "0.2% ropivacaine",
          "type": "DEVICE"
        },
        {
          "name": "saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 32,
      "start_date": "2010-07",
      "completion_date": "2017-09-07",
      "has_results": true,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01167907"
    },
    {
      "nct_id": "NCT01457326",
      "title": "Early Standardized Weight Bearing Utilizing Immersion Therapy Following Periarticular Lower Extremity Fractures",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lower Extremity Periarticular Fractures"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 122,
      "start_date": "2009-06",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-07-14",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01457326"
    },
    {
      "nct_id": "NCT05521958",
      "title": "Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Shaft Fracture",
        "Tibial Plateau Fracture"
      ],
      "interventions": [
        {
          "name": "Acute injury without compartment syndrome",
          "type": "PROCEDURE"
        },
        {
          "name": "Acute injury with compartment syndrome",
          "type": "PROCEDURE"
        },
        {
          "name": "Exertional compartment syndrome",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-06-10",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05521958"
    },
    {
      "nct_id": "NCT05876897",
      "title": "US vs MRI for Stress Injuries",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stress Fracture"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ryan Kruse",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 25,
      "start_date": "2021-02-03",
      "completion_date": "2024-04-01",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05876897"
    },
    {
      "nct_id": "NCT04612478",
      "title": "Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Injury"
      ],
      "interventions": [
        {
          "name": "Self-Directed Exercise Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Clinic-Based Physical",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 150,
      "start_date": "2018-03-14",
      "completion_date": "2023-11-02",
      "has_results": false,
      "last_update_posted_date": "2024-01-31",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Greenville, South Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04612478"
    },
    {
      "nct_id": "NCT06586814",
      "title": "Suture Versus Staples for Wound Closure in Orthopaedic Trauma Surgery",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity Fracture"
      ],
      "interventions": [
        {
          "name": "Suture",
          "type": "OTHER"
        },
        {
          "name": "Staple",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-08-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-05-22T08:21:45.043Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06586814"
    }
  ]
}