{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=16",
    "query": {
      "condition": "Extremity Injuries Lower",
      "page": 16
    },
    "page_size": 10
  },
  "pagination": {
    "page": 16,
    "page_size": 10,
    "total_count": 803,
    "total_pages": 81,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=17&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=15&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T03:32:28.843Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07142408",
      "title": "The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate (4%)",
          "type": "DRUG"
        },
        {
          "name": "Mupirocin 2% Ointment",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cooper Norcross Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 848,
      "start_date": "2023-03-13",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2025-08-26",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Marlton, New Jersey",
      "locations": [
        {
          "city": "Marlton",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07142408"
    },
    {
      "nct_id": "NCT00644397",
      "title": "Plate Fixation of Distal Femur Fractures: A Protocol for a Study of Two Plate Options",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Femoral Fractures"
      ],
      "interventions": [
        {
          "name": "95-degree Angled Blade Plate",
          "type": "DEVICE"
        },
        {
          "name": "4.5mm Condylar Locking Plate",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MetroHealth Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2006-05",
      "completion_date": "2019-01",
      "has_results": false,
      "last_update_posted_date": "2019-08-13",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00644397"
    },
    {
      "nct_id": "NCT05274022",
      "title": "Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Femoral Fracture",
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "Standard of Care Physical Therapy Program",
          "type": "OTHER"
        },
        {
          "name": "Speed Walking Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brian W. Noehren",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 66,
      "start_date": "2022-03-03",
      "completion_date": "2025-12-18",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 2,
      "location_summary": "Lexington, Kentucky • Nashville, Tennessee",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05274022"
    },
    {
      "nct_id": "NCT02855060",
      "title": "Pre-hospital Advanced Therapies for Control of Hemorrhage - Pelvis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemorrhage",
        "Pelvic Fracture"
      ],
      "interventions": [
        {
          "name": "Pelvic Binder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 50,
      "start_date": "2016-07",
      "completion_date": "2018-12",
      "has_results": true,
      "last_update_posted_date": "2022-04-21",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02855060"
    },
    {
      "nct_id": "NCT00240396",
      "title": "Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibia Fracture",
        "Femur Fracture",
        "Humerus Fracture"
      ],
      "interventions": [
        {
          "name": "Narcotics alone",
          "type": "DRUG"
        },
        {
          "name": "Narcotics and NSAIDS",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 0,
      "start_date": "2005-10",
      "completion_date": "2007-09-24",
      "has_results": false,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00240396"
    },
    {
      "nct_id": "NCT01552551",
      "title": "Assessment and Referral Versus Exercise in Primary Prevention of Falls: PA Healthy Steps Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Extremity Weakness Distal",
        "Distorted; Balance"
      ],
      "interventions": [
        {
          "name": "Assessment and education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Steps with Falls Case Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Steps in Motion",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "50 Years to 100 Years"
      },
      "enrollment_count": 189,
      "start_date": "2012-05",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2015-12-30",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01552551"
    },
    {
      "nct_id": "NCT01667887",
      "title": "Plating of Distal Femur Fractures by Far Cortical Locking Using MotionLoc Screws",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fracture of Distal Femur"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Legacy Biomechanics Laboratory",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2011-04",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2013-01-29",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01667887"
    },
    {
      "nct_id": "NCT05209347",
      "title": "Custom Dynamic Orthoses to Reduce Articular Contact Stress",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Post-traumatic Osteoarthritis",
        "Osteoarthritis Ankle"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2024-12",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05209347"
    },
    {
      "nct_id": "NCT03644849",
      "title": "Evaluating the Safety and Efficacy of Fractionated Carbon Dioxide Therapy in Postoperative Lower Extremity Wound Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "CO2RE® (Syneron Candela Corp, Wayland, MA)",
          "type": "DEVICE"
        },
        {
          "name": "Sham laser treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 48,
      "start_date": "2018-09-28",
      "completion_date": "2020-11-19",
      "has_results": true,
      "last_update_posted_date": "2022-01-11",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 2,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03644849"
    },
    {
      "nct_id": "NCT02820363",
      "title": "Study Evaluating CERAMENT™|G in Open Diaphyseal Tibial Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Fracture"
      ],
      "interventions": [
        {
          "name": "CERAMENT|G",
          "type": "DEVICE"
        },
        {
          "name": "SOC treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "BONESUPPORT AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 201,
      "start_date": "2017-02-14",
      "completion_date": "2021-07-31",
      "has_results": false,
      "last_update_posted_date": "2021-08-10",
      "last_synced_at": "2026-11-15T03:32:28.843Z",
      "location_count": 17,
      "location_summary": "Birmingham, Alabama • Irvine, California • Los Angeles, California + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02820363"
    }
  ]
}