{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=23",
    "query": {
      "condition": "Extremity Injuries Lower",
      "page": 23
    },
    "page_size": 10
  },
  "pagination": {
    "page": 23,
    "page_size": 10,
    "total_count": 803,
    "total_pages": 81,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=24&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=22&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T04:30:44.206Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00951080",
      "title": "SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ulcers",
        "Wounds"
      ],
      "interventions": [
        {
          "name": "Traditional NPWT System",
          "type": "DEVICE"
        },
        {
          "name": "SNaP Wound Care System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "3M",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2009-07",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2022-08-01",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 17,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 14 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Poway",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00951080"
    },
    {
      "nct_id": "NCT04285879",
      "title": "Blood Flow Restriction Training (BFR) in an Adolescent Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Flow Restriction",
        "ACL Tear",
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction using Delfi Personalized Tourniquet System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Connecticut Children's Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 47,
      "start_date": "2020-12-15",
      "completion_date": "2023-10-16",
      "has_results": true,
      "last_update_posted_date": "2024-07-17",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04285879"
    },
    {
      "nct_id": "NCT05889559",
      "title": "Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Compartment Syndrome",
        "Fracture, Bone",
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "Tissue Ultrafiltration Catheters",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-01-01",
      "completion_date": "2028-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-11-12",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 4,
      "location_summary": "Baltimore, Maryland • Minneapolis, Minnesota • Charlotte, North Carolina + 1 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05889559"
    },
    {
      "nct_id": "NCT04113785",
      "title": "In Vivo Kinematics for Subjects Implanted With Klassic Total Knee Arthroplasty (TKA)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Total Knee Arthroplasty",
        "Osteo Arthritis Knee",
        "Knee Implant",
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Klassic Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2018-10-01",
      "completion_date": "2019-06-05",
      "has_results": true,
      "last_update_posted_date": "2019-11-15",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04113785"
    },
    {
      "nct_id": "NCT01379118",
      "title": "Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Joint Disease",
        "Osteoarthritis",
        "Knee Injury, Trauma",
        "Connective Tissue Disorder",
        "Pain",
        "Loss of Function"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2012-07",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-09-15",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "San Bernardino, California",
      "locations": [
        {
          "city": "San Bernardino",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01379118"
    },
    {
      "nct_id": "NCT03966027",
      "title": "Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures"
      ],
      "interventions": [
        {
          "name": "Postoperative protocol (Immediate weight bearing)",
          "type": "OTHER"
        },
        {
          "name": "Postoperative Protocol (Delayed Weight Bearing)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kyle Schweser MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2020-08-01",
      "completion_date": "2028-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03966027"
    },
    {
      "nct_id": "NCT06496035",
      "title": "Blood Flow Restriction Training in Patients With Lower Extremity Fractures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Fractures",
        "Lower Extremity Fracture"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction with low load exercise",
          "type": "DEVICE"
        },
        {
          "name": "Therapeutic Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Denver Health and Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-11-01",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06496035"
    },
    {
      "nct_id": "NCT06589115",
      "title": "Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Plateau Fractures"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction Cuff",
          "type": "OTHER"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-12-01",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06589115"
    },
    {
      "nct_id": "NCT01294098",
      "title": "Efficacy Study of Femoral Nerve Block in Children With a Femur Fracture",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Femoral Fractures",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Marcaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "7 Years to 14 Years"
      },
      "enrollment_count": 2,
      "start_date": "2011-02",
      "completion_date": "2014-10-08",
      "has_results": true,
      "last_update_posted_date": "2018-03-30",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 2,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01294098"
    },
    {
      "nct_id": "NCT06668376",
      "title": "A Study to Evaluate the Incrediwear Products Immediately After ACL Repair",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Medial Collateral Ligament"
      ],
      "interventions": [
        {
          "name": "Leg Sleeve",
          "type": "DEVICE"
        },
        {
          "name": "Placebo",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Texas Bone and Joint",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 90,
      "start_date": "2024-10-29",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2024-11-01",
      "last_synced_at": "2026-11-15T04:30:44.206Z",
      "location_count": 1,
      "location_summary": "Denton, Texas",
      "locations": [
        {
          "city": "Denton",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06668376"
    }
  ]
}