{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=31",
    "query": {
      "condition": "Extremity Injuries Lower",
      "page": 31
    },
    "page_size": 10
  },
  "pagination": {
    "page": 31,
    "page_size": 10,
    "total_count": 803,
    "total_pages": 81,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=32&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=30&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T05:42:48.576Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05442879",
      "title": "Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries",
        "Lower Extremity Problem"
      ],
      "interventions": [
        {
          "name": "Knowledge Translation Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational handout",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "14 Years to 19 Years"
      },
      "enrollment_count": 671,
      "start_date": "2022-07-01",
      "completion_date": "2024-08-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 1,
      "location_summary": "Flint, Michigan",
      "locations": [
        {
          "city": "Flint",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05442879"
    },
    {
      "nct_id": "NCT00635479",
      "title": "Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Fractures",
        "Acetabular Fractures",
        "Hip Fractures"
      ],
      "interventions": [
        {
          "name": "VAC device",
          "type": "DEVICE"
        },
        {
          "name": "Gauze dressing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 115,
      "start_date": "2008-03",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2017-12-11",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00635479"
    },
    {
      "nct_id": "NCT05153863",
      "title": "C Scope Visualization System Prospective Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries and Disorders",
        "Shoulder Disease",
        "Shoulder Injuries"
      ],
      "interventions": [
        {
          "name": "C Scope Visualization System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIT Ortho",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2022-01-20",
      "completion_date": "2023-07-07",
      "has_results": false,
      "last_update_posted_date": "2023-12-01",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 1,
      "location_summary": "Henderson, Nevada",
      "locations": [
        {
          "city": "Henderson",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05153863"
    },
    {
      "nct_id": "NCT03035266",
      "title": "The Effect of Blood Flow Restriction Training on Muscle Atrophy Following Knee Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction",
          "type": "OTHER"
        },
        {
          "name": "Standard rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Keller Army Community Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 22,
      "start_date": "2017-04-05",
      "completion_date": "2020-03-12",
      "has_results": false,
      "last_update_posted_date": "2020-08-21",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 2,
      "location_summary": "West Point, New York • Fort Bragg, North Carolina",
      "locations": [
        {
          "city": "West Point",
          "state": "New York"
        },
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03035266"
    },
    {
      "nct_id": "NCT02089880",
      "title": "Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Poliomyelitis",
        "Post-polio Syndrome",
        "Arthritis",
        "Lower Motor Neurone Lesion"
      ],
      "interventions": [
        {
          "name": "C-brace",
          "type": "DEVICE"
        },
        {
          "name": "Stance control orthosis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 24,
      "start_date": "2014-02",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-01",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02089880"
    },
    {
      "nct_id": "NCT00888550",
      "title": "Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibia Fracture"
      ],
      "interventions": [
        {
          "name": "Post-Op Splinting",
          "type": "PROCEDURE"
        },
        {
          "name": "No Splinting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Denver Health and Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2007-08",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-09-29",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00888550"
    },
    {
      "nct_id": "NCT07828613",
      "title": "Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Open Tibia Fracture",
        "Open Dislocation of Ankle",
        "Extremity Fracture Lower",
        "Extremity Injuries Lower"
      ],
      "interventions": [
        {
          "name": "Accelerated Flap Coverage Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care Flap Timing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 356,
      "start_date": "2027-01-01",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-18",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 31,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Sacramento, California + 24 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07828613"
    },
    {
      "nct_id": "NCT04925791",
      "title": "Does Limb Pre-Conditioning Reduce Pain After Hip Arthroscopy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip Injuries",
        "Hip Dislocation",
        "Hip Fractures"
      ],
      "interventions": [
        {
          "name": "standardized pre-conditioning treatment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Partial occlusion",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 68,
      "start_date": "2021-10-18",
      "completion_date": "2023-10-20",
      "has_results": false,
      "last_update_posted_date": "2024-08-20",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04925791"
    },
    {
      "nct_id": "NCT01670617",
      "title": "DeNovo NT Natural Tissue Graft Stratified Knee Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Defect of Articular Cartilage",
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Particulated Juvenile Articular Cartilage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Zimmer Orthobiologics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 90,
      "start_date": "2012-03",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-26",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 16,
      "location_summary": "Los Angeles, California • San Deigo, California • Aurora, Colorado + 13 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Deigo",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01670617"
    },
    {
      "nct_id": "NCT02090140",
      "title": "Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Lesion of Articular Cartilage of Knee"
      ],
      "interventions": [
        {
          "name": "ADSC Application",
          "type": "PROCEDURE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 17,
      "start_date": "2015-11",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-04-25",
      "last_synced_at": "2026-11-15T05:42:48.576Z",
      "location_count": 3,
      "location_summary": "Redwood City, California • Santa Monica, California • Denver, Colorado",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02090140"
    }
  ]
}