{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=4",
    "query": {
      "condition": "Extremity Injuries Lower",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 803,
    "total_pages": 81,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Extremity+Injuries+Lower&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T00:59:30.129Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03365908",
      "title": "Pain Management of ACL Reconstruction",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Adductor Canal Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Ropivacaine injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 60,
      "start_date": "2017-10-09",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03365908"
    },
    {
      "nct_id": "NCT03711747",
      "title": "Indications for Osteochondral Allograft Transplantation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-Traumatic Osteoarthritis of Ankle",
        "Ankle Osteoarthritis",
        "Ankle Injuries"
      ],
      "interventions": [
        {
          "name": "Osteochondral allograft ankle",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-01-01",
      "completion_date": "2022-10-01",
      "has_results": false,
      "last_update_posted_date": "2022-11-17",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03711747"
    },
    {
      "nct_id": "NCT02292004",
      "title": "Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury",
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "ACL Repair with MIACH Scaffold",
          "type": "DEVICE"
        },
        {
          "name": "Standard ACL Reconstruction",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Miach Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2015-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02292004"
    },
    {
      "nct_id": "NCT06050668",
      "title": "Essential Amino Acid Supplementation for Femoral Fragility Fractures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Femoral Fracture",
        "Fragility Fracture",
        "Muscle Atrophy"
      ],
      "interventions": [
        {
          "name": "Essential Amino Acid Supplementation",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Michael C Willey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-06-17",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-10-07",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa • Eugene, Oregon",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06050668"
    },
    {
      "nct_id": "NCT05317676",
      "title": "Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tibial Fractures",
        "Fibula Fracture",
        "Knee Fracture"
      ],
      "interventions": [
        {
          "name": "Palmitoylethanolamide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2023-05",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2023-05-09",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05317676"
    },
    {
      "nct_id": "NCT05245097",
      "title": "Mitigation of Major Hip Injury Due to Fall With a Smart Belt",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hip Injuries",
        "Fractures, Hip",
        "Fall Injury",
        "Fall Risk",
        "Osteoporosis",
        "Osteoporosis Risk"
      ],
      "interventions": [
        {
          "name": "Tango Belt",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care (SOC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "ActiveProtective Technologies, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 471,
      "start_date": "2022-03-29",
      "completion_date": "2023-11-03",
      "has_results": true,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 10,
      "location_summary": "Sacramento, California • Bensalem, Pennsylvania • Gwynedd, Pennsylvania + 7 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Bensalem",
          "state": "Pennsylvania"
        },
        {
          "city": "Gwynedd",
          "state": "Pennsylvania"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        },
        {
          "city": "Lansdale",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05245097"
    },
    {
      "nct_id": "NCT01433718",
      "title": "Decreasing Knee Injury Risk Factors With Neuromuscular Training",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL",
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "Neuromuscular and Resistance Training",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Ohio University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "20 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 20 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2011-09",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2017-04-21",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 1,
      "location_summary": "Athens, Ohio",
      "locations": [
        {
          "city": "Athens",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01433718"
    },
    {
      "nct_id": "NCT05292313",
      "title": "Dual Implant Versus Single Implant Distal End of Femur",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distal Femur Fracture"
      ],
      "interventions": [
        {
          "name": "Single distal femur implant",
          "type": "PROCEDURE"
        },
        {
          "name": "Dual distal femur implants",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "60 Years to 100 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-03-14",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 5,
      "location_summary": "Rochester, Minnesota • New York, New York • Portland, Oregon + 2 more",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Harrisburg",
          "state": "Pennsylvania"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05292313"
    },
    {
      "nct_id": "NCT00623389",
      "title": "Evaluation of an Advanced Lower Extremity Neuroprostheses",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Stroke",
        "Paralysis",
        "Tetraplegia",
        "Paraplegia"
      ],
      "interventions": [
        {
          "name": "IST (Implanted Stimulator-Telemeter)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2018-06-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00623389"
    },
    {
      "nct_id": "NCT06635668",
      "title": "Baseline ACL Injury Risk Screening and Normative Data",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ACL Injury",
        "Anterior Cruciate Ligament Injuries",
        "Musculoskeletal Injury"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Sanford Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "10 Years to 65 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2022-07-19",
      "completion_date": "2033-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-11-15T00:59:30.129Z",
      "location_count": 1,
      "location_summary": "Fargo, North Dakota",
      "locations": [
        {
          "city": "Fargo",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06635668"
    }
  ]
}