{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eye+Diseases+Hereditary&page=18", "query": { "condition": "Eye Diseases Hereditary", "page": 18 }, "page_size": 10 }, "pagination": { "page": 18, "page_size": 10, "total_count": 807, "total_pages": 81, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eye+Diseases+Hereditary&page=19&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eye+Diseases+Hereditary&page=17&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-15T17:05:35.440Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07404111", "title": "A Study of VV-14305 for the Treatment of Thyroid Eye Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Thyroid Eye Disease (TED)" ], "interventions": [ { "name": "VV-14305", "type": "GENETIC" }, { "name": "Sham (No Treatment)", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "Kriya Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 135, "start_date": "2026-05-01", "completion_date": "2029-08", "has_results": false, "last_update_posted_date": "2026-08-27", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 3, "location_summary": "Livonia, Michigan • Las Vegas, Nevada • Erie, Pennsylvania", "locations": [ { "city": "Livonia", "state": "Michigan" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "Erie", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07404111" }, { "nct_id": "NCT01931644", "title": "At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "All Diagnosed Health Conditions", "ADD/ADHD", "Alopecia Areata", "Ankylosing Spondylitis", "Asthma", "Atopic Dermatitis Eczema", "Beta Thalassemia", "Bipolar Disorder", "Breast Cancer", "Celiac Disease", "Cervical Cancer", "Chronic Inflammatory Demyelinating Polyneuropathy", "Chronic Kidney Diseases", "Chronic Obstructive Pulmonary Disease", "Colon Cancer", "Colorectal Cancer", "Crohn's Disease", "Cystic Fibrosis", "Depression", "Diabetes Mellitus", "Duchenne Muscular Dystrophy", "Endometriosis", "Epilepsy", "Facioscapulohumeral Muscular Dystrophy", "G6PD Deficiency", "General Anxiety Disorder", "Hepatitis B", "Hereditary Hemorrhagic Telangiectasia", "HIV/AIDS", "Human Papilloma Virus", "Huntington's Disease", "Idiopathic Thrombocytopenic Purpura", "Insomnia", "Kidney Cancer", "Leukemia", "Lung Cancer", "Lupus Nephritis", "Lymphoma", "Melanoma", "Multiple Myeloma", "Multiple Sclerosis", "Myositis", "Myotonic Dystrophy", "Ovarian Cancer", "Pancreatic Cancer", "Parkinson's Disease", "Polycystic Kidney Diseases", "Prostate Cancer", "Psoriasis", "Psoriatic Arthritis", "Rosacea", "Scleroderma", "Sickle Cell Anemia", "Sickle Cell Trait", "Sjogren's Syndrome", "Skin Cancer", "Spinal Muscular Atrophy", "Systemic Lupus Erythematosus", "Thrombotic Thrombocytopenic Purpura", "Trisomy 21", "Ulcerative Colitis" ], "interventions": [], "intervention_types": [], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 17667, "start_date": "2013-07", "completion_date": "2024-04", "has_results": false, "last_update_posted_date": "2024-04-18", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931644" }, { "nct_id": "NCT00346333", "title": "Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin A", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Retinitis Pigmentosa" ], "interventions": [ { "name": "Lutein", "type": "DRUG" }, { "name": "Cornstarch control", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT" ], "sponsor": "National Eye Institute (NEI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 240, "start_date": "2003-07", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2014-01-31", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00346333" }, { "nct_id": "NCT06307626", "title": "A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Thyroid Eye Disease" ], "interventions": [ { "name": "Efgartigimod PH20 SC", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo PH20 SC", "type": "OTHER" } ], "intervention_types": [ "COMBINATION_PRODUCT", "OTHER" ], "sponsor": "argenx", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 105, "start_date": "2024-03-28", "completion_date": "2026-02-12", "has_results": false, "last_update_posted_date": "2026-03-16", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 11, "location_summary": "Los Angeles, California • Mission Hills, California • Rancho Cordova, California + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Rancho Cordova", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Boynton Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06307626" }, { "nct_id": "NCT04839315", "title": "COVID-19 Vaccination in Rheumatic Disease Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Systemic Lupus Erythematosus", "Sjogren's Syndrome", "Inflammatory Myositis", "Psoriatic Arthritis", "Gout", "Ankylosing Spondylitis", "Arthritis of Multiple Sites Associated With Inflammatory Bowel Disease (Diagnosis)", "Osteoarthritis" ], "interventions": [ { "name": "mRNA COVD19 vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 58, "start_date": "2021-02-15", "completion_date": "2022-02-09", "has_results": false, "last_update_posted_date": "2022-06-03", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04839315" }, { "nct_id": "NCT04049266", "title": "A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Wet Macular Degeneration" ], "interventions": [ { "name": "KSI-301", "type": "DRUG" }, { "name": "Aflibercept", "type": "DRUG" }, { "name": "Sham Procedure", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Kodiak Sciences Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 559, "start_date": "2019-10-08", "completion_date": "2022-04-26", "has_results": true, "last_update_posted_date": "2024-07-18", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 59, "location_summary": "Phoenix, Arizona • Springdale, Arkansas • Bakersfield, California + 53 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Springdale", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Fresno", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04049266" }, { "nct_id": "NCT05573984", "title": "Natural History of PRPF31 Mutation-Associated Retinal Dystrophy", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Retinitis Pigmentosa", "Eye Diseases, Hereditary", "Retinal Dystrophies", "Retinal Dystrophy Rod", "Retinal Dystrophy Rod Progressive" ], "interventions": [], "intervention_types": [], "sponsor": "PYC Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": null, "sex": "ALL", "summary": "10 Years and older" }, "enrollment_count": 50, "start_date": "2022-07-07", "completion_date": "2026-11-01", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 5, "location_summary": "San Francisco, California • Jacksonville, Florida • Ann Arbor, Michigan + 2 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Portland", "state": "Oregon" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05573984" }, { "nct_id": "NCT00176826", "title": "T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Hemophagocytic Lymphohistiocytosis", "X-Linked Lymphoproliferative Disorders", "Chediak-Higashi Syndrome", "Griscelli Syndrome", "Immunologic Diseases", "Langerhans-Cell Histiocytosis", "Hematologic Diseases" ], "interventions": [ { "name": "Stem Cell Transplant", "type": "PROCEDURE" }, { "name": "Myeloablative conditioning regimen", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "55 Years", "sex": "ALL", "summary": "Up to 55 Years" }, "enrollment_count": 22, "start_date": "2000-09", "completion_date": "2015-08", "has_results": true, "last_update_posted_date": "2018-01-23", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00176826" }, { "nct_id": "NCT02909985", "title": "Visual Activity Evoked by Infrared in Humans After Dark Adaptation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Age Related Macular Degeneration", "Retinitis Pigmentosa", "Congenital Stationary Night Blindness", "Colorblindness" ], "interventions": [ { "name": "Tungsten halogen light with narrow bandpass filters", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of New Mexico", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 21, "start_date": "2015-09", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2024-12-13", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT02909985" }, { "nct_id": "NCT02416622", "title": "Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "X-linked Retinoschisis" ], "interventions": [ { "name": "rAAV2tYF-CB-hRS1", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Beacon Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "MALE", "summary": "6 Years and older · Male only" }, "enrollment_count": 27, "start_date": "2015-05", "completion_date": "2023-05-09", "has_results": true, "last_update_posted_date": "2023-06-12", "last_synced_at": "2026-10-15T17:05:35.440Z", "location_count": 9, "location_summary": "San Francisco, California • Miami, Florida • Baltimore, Maryland + 6 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02416622" } ] }