{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eye+Irritation", "query": { "condition": "Eye Irritation" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 11, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eye+Irritation&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-22T18:05:58.757Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02854137", "title": "Evaluation of the Irritation Potential of Sunscreen Products in Human Eyes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sunscreening Agents" ], "interventions": [ { "name": "BAY987521", "type": "DRUG" }, { "name": "Control", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 23, "start_date": "2015-10-14", "completion_date": "2015-10-14", "has_results": false, "last_update_posted_date": "2018-12-12", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "St. Petersburg, Florida", "locations": [ { "city": "St. Petersburg", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02854137" }, { "nct_id": "NCT01391364", "title": "A Study to Evaluate a Modified Contact Lens", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia" ], "interventions": [ { "name": "SofLens in investigational solution", "type": "DEVICE" }, { "name": "SofLens in currently marketed solution", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 438, "start_date": "2011-04", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2020-09-30", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01391364" }, { "nct_id": "NCT00803387", "title": "Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Ocular Dryness", "Ocular Irritation", "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Travaprost without BAC (Travatan Z)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "United States Air Force", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 33, "start_date": "2008-04", "completion_date": "2008-09", "has_results": false, "last_update_posted_date": "2008-12-05", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "Lackland Air Force Base, Texas", "locations": [ { "city": "Lackland Air Force Base", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00803387" }, { "nct_id": "NCT05832996", "title": "Cool vs Room-temperature Artificial Tears", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis)", "Central Retinal Vein Occlusion With Macular Edema", "Exudative Age-Related Macular Degeneration, Unspecified Eye", "Cystoid Macular Edema", "Ocular Surface Disease", "Dry Eye Sensation", "Eye Pain" ], "interventions": [ { "name": "Refresh Plus Preservative-free Lubricant Eye Drops", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "105 Years", "sex": "ALL", "summary": "18 Years to 105 Years" }, "enrollment_count": 124, "start_date": "2022-03-01", "completion_date": "2022-07-06", "has_results": true, "last_update_posted_date": "2025-03-04", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT05832996" }, { "nct_id": "NCT02728856", "title": "Evaluation of the Irritation Potential of Products in Human Eyes.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sunscreening Agents" ], "interventions": [ { "name": "Sunscreen Spray SPF50 Z15-034(BAY987516)", "type": "OTHER" }, { "name": "Shampoo Control", "type": "OTHER" }, { "name": "Sunscreen Spray SPF50 Z15-038(BAY987516)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 48, "start_date": "2016-02-27", "completion_date": "2016-02-27", "has_results": false, "last_update_posted_date": "2017-03-31", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "St. Petersburg, Florida", "locations": [ { "city": "St. Petersburg", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02728856" }, { "nct_id": "NCT06538662", "title": "An Investigation of FID 123320 for the Reduction of Ocular Redness in Pediatric and Adult Populations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ocular Redness", "Eye Irritation" ], "interventions": [ { "name": "FID 123320 Ophthalmic Solution", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": null, "sex": "ALL", "summary": "5 Years and older" }, "enrollment_count": 283, "start_date": "2024-10-07", "completion_date": "2025-04-03", "has_results": false, "last_update_posted_date": "2026-01-22", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 10, "location_summary": "Azusa, California • Newport Beach, California • Colorado Springs, Colorado + 7 more", "locations": [ { "city": "Azusa", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06538662" }, { "nct_id": "NCT02163824", "title": "Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ocular Infections, Irritations and Inflammations" ], "interventions": [ { "name": "KPI-121 0.25%", "type": "DRUG" }, { "name": "KPI-121 1.0%", "type": "DRUG" }, { "name": "Vehicle of KPI-121 0.25%", "type": "DRUG" }, { "name": "Vehicle of KPI-121 1.0%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kala Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 380, "start_date": "2014-05", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2021-01-29", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 23, "location_summary": "Artesia, California • Mission Hills, California • Rancho Cordova, California + 17 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Rancho Cordova", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Morrow", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02163824" }, { "nct_id": "NCT06583395", "title": "Quest to Analyze One Thousand Humans Meditating", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyotrophic Lateral Sclerosis (ALS)", "Angina, Stable", "Anxiety", "Asthma", "Atrial Fibrillation", "Cancer Brain", "Cancer, Breast", "Cancer Colon", "Cancer, Lung", "Cancer, Ovarian", "Cancer Prostate", "Cancer Skin", "Throat Cancer", "Lymphoma", "Cancer, Thyroid", "Cancer, Other", "Cerebral Palsy", "Chronic Fatigue Syndrome", "Cluster Headache", "Chronic Obstructive Pulmonary Disease (COPD)", "Chronic Kidney Diseases", "Crohn Disease", "Deafness", "Depression", "Diabetes", "Eczema", "Epilepsy", "Fibroids", "Fibromyalgia", "Heart Failure", "Hypertension", "Hyperthyroidism", "Hypothyroidism", "Irritable Bowel Syndrome (IBS)", "Infertility", "Lyme Disease", "Macular Degeneration", "Migraine", "Multiple Allergies", "Multiple Sclerosis", "Osteoarthritis", "Osteoporosis", "Ovarian Cysts", "Parkinson Disease", "Phantom Limb Pain", "Psoriasis", "Post Traumatic Stress Disorder (PTSD)", "Rheumatoid Arthritis", "Sjogrens Disease", "Spinal Cord Injury", "Spinal Stenosis", "Stroke", "Tension Headache", "Tinnitus", "Ulcerative Colitis" ], "interventions": [ { "name": "Advanced multi-component meditation practice", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Tobias Moeller-Bertram", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 3000, "start_date": "2021-12-05", "completion_date": "2025-03-25", "has_results": false, "last_update_posted_date": "2024-11-01", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "Palm Desert, California", "locations": [ { "city": "Palm Desert", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06583395" }, { "nct_id": "NCT05615805", "title": "The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Intravitreal Injection", "Ocular Rinse", "Age-Related Macular Degeneration", "Diabetic Macular Edema", "Cystoid Macular Edema" ], "interventions": [ { "name": "OSDI questionnaire", "type": "OTHER" }, { "name": "SPEEDII questionnaire", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 142, "start_date": "2021-03-01", "completion_date": "2021-10-01", "has_results": false, "last_update_posted_date": "2023-04-25", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "Oklahoma City, Oklahoma", "locations": [ { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT05615805" }, { "nct_id": "NCT03945071", "title": "The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dry Eye Syndromes", "Dry Eye", "Ocular Surface Disease" ], "interventions": [ { "name": "Punctal plug", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 126, "start_date": "2019-06-01", "completion_date": "2020-10-18", "has_results": false, "last_update_posted_date": "2023-12-07", "last_synced_at": "2026-07-22T18:05:58.757Z", "location_count": 1, "location_summary": "Oklahoma City, Oklahoma", "locations": [ { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT03945071" } ] }