{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eyelid+Deformity",
    "query": {
      "condition": "Eyelid Deformity"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Eyelid+Deformity&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T23:05:53.270Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02230761",
      "title": "Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lower Eyelid Steatoblepharon (Excess Eyelid Fat)"
      ],
      "interventions": [
        {
          "name": "XOPH5 Ointment",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Topokine Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 90,
      "start_date": "2014-09",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-02-08",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02230761"
    },
    {
      "nct_id": "NCT03280069",
      "title": "Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Skin Laxity",
        "Meibomian Gland Dysfunction"
      ],
      "interventions": [
        {
          "name": "THERMIeyes® 20 RF System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ophthalmic Consultants of Long Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2017-07-25",
      "completion_date": "2019-07-31",
      "has_results": false,
      "last_update_posted_date": "2017-09-12",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 1,
      "location_summary": "Lynbrook, New York",
      "locations": [
        {
          "city": "Lynbrook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03280069"
    },
    {
      "nct_id": "NCT07133464",
      "title": "CDH1-associated Blepharocheilodontic Syndrome Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Blepharocheilodontic Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2025-06-17",
      "completion_date": "2040-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-21",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07133464"
    },
    {
      "nct_id": "NCT01738243",
      "title": "Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Thyroid Eye Disease"
      ],
      "interventions": [
        {
          "name": "Hyaluronic Acid Gel injection",
          "type": "DRUG"
        },
        {
          "name": "Saline injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 2,
      "start_date": "2013-12",
      "completion_date": "2021-09",
      "has_results": false,
      "last_update_posted_date": "2021-10-04",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01738243"
    },
    {
      "nct_id": "NCT04585217",
      "title": "A Comparison of the Effect of Suture Material on Blepharoplasty Incision",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dermatochalasis",
        "Ptosis, Eyelid"
      ],
      "interventions": [
        {
          "name": "Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 23,
      "start_date": "2020-05-30",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-10-23",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04585217"
    },
    {
      "nct_id": "NCT05956535",
      "title": "Air Optix® Night and Day® Aqua Therapeutic Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bullous Keratopathy",
        "Corneal Erosion",
        "Entropion",
        "Corneal Edema",
        "Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2023-09-26",
      "completion_date": "2024-10-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-13",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 3,
      "location_summary": "Delray Beach, Florida • St Louis, Missouri • Fort Worth, Texas",
      "locations": [
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05956535"
    },
    {
      "nct_id": "NCT06511453",
      "title": "Acupressure in Patients With Sickle Cell Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Verum Acupressure (using AcuWand)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Acupressure (using AcuWand)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 300,
      "start_date": "2024-03-07",
      "completion_date": "2032-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 2,
      "location_summary": "Irvine, California • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06511453"
    },
    {
      "nct_id": "NCT05945069",
      "title": "Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects with Dry Eye Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eyelid Diseases",
        "Eyelid Movement Disorders",
        "Dry Eye",
        "Dry Eye Syndromes",
        "Skin Laxity"
      ],
      "interventions": [
        {
          "name": "TriLift device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lumenis Be Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2023-08-01",
      "completion_date": "2024-09-05",
      "has_results": false,
      "last_update_posted_date": "2025-03-10",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05945069"
    },
    {
      "nct_id": "NCT05294640",
      "title": "Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Eyelid Tumor",
        "Eyelid Bump",
        "Eyelid Deformity",
        "Eyelid Abscess",
        "Eyelid Boil",
        "Eyelid Papilloma",
        "Anesthesia, Local",
        "Ophthalmology"
      ],
      "interventions": [
        {
          "name": "0.9% Bacteriostatic Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "Eyelid Lesion Removal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 95,
      "start_date": "2022-05-17",
      "completion_date": "2023-02-21",
      "has_results": true,
      "last_update_posted_date": "2025-07-08",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05294640"
    },
    {
      "nct_id": "NCT05891106",
      "title": "AONDA Therapeutic Indication Study I",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bullous Keratopathy",
        "Corneal Erosion",
        "Entropion",
        "Corneal Edema",
        "Corneal Dystrophy",
        "Corneal Ulcer",
        "Foreign Body in Cornea",
        "Bell Palsy",
        "Keratoconjunctivitis",
        "Filamentary Keratitis",
        "Sicca Syndrome; Keratoconjunctivitis (Etiology)"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2023-06-28",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2023-07-20",
      "last_synced_at": "2026-07-23T23:05:53.270Z",
      "location_count": 3,
      "location_summary": "Orlando, Florida • Franklin Park, Illinois • Memphis, Tennessee",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Franklin Park",
          "state": "Illinois"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05891106"
    }
  ]
}