{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=FXS&page=2",
    "query": {
      "condition": "FXS",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=FXS&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T20:14:04.285Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00879515",
      "title": "Examining Social, Emotional, and Cognitive Functioning in People With Fragile X and Down Syndromes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anxiety Disorders",
        "Child Developmental Disorders, Pervasive"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "5 Years to 25 Years"
      },
      "enrollment_count": 511,
      "start_date": "2005-10",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00879515"
    },
    {
      "nct_id": "NCT03140813",
      "title": "An Initial Study of AZD7325 in Adults With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "AZD7325 (High-Dose)",
          "type": "DRUG"
        },
        {
          "name": "AZD7325 (Low-Dose)",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 15,
      "start_date": "2018-01-16",
      "completion_date": "2020-06-18",
      "has_results": false,
      "last_update_posted_date": "2021-02-08",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03140813"
    },
    {
      "nct_id": "NCT04141163",
      "title": "Metformin in Patients With Fragile X",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Metformin",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rowan University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 40,
      "start_date": "2019-10-29",
      "completion_date": "2021-03",
      "has_results": false,
      "last_update_posted_date": "2019-10-31",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Stratford, New Jersey",
      "locations": [
        {
          "city": "Stratford",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04141163"
    },
    {
      "nct_id": "NCT02920892",
      "title": "AFQ056 for Language Learning in Children With FXS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "AFQ056",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Language Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Elizabeth Berry-Kravis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "32 Months",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "32 Months to 6 Years"
      },
      "enrollment_count": 110,
      "start_date": "2017-08-17",
      "completion_date": "2022-05-17",
      "has_results": true,
      "last_update_posted_date": "2023-10-10",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 14,
      "location_summary": "Davis, California • Denver, Colorado • New Haven, Connecticut + 11 more",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02920892"
    },
    {
      "nct_id": "NCT00334971",
      "title": "Aromatase Activity and Ovarian Growth Factors in African-American Versus Caucasian Women",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Follicle Aspiration",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 116,
      "start_date": "2004-09",
      "completion_date": "2018-01",
      "has_results": false,
      "last_update_posted_date": "2013-11-06",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00334971"
    },
    {
      "nct_id": "NCT06139172",
      "title": "Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Telomeric 22Q13 Monosomy Syndrome",
        "Tuberous Sclerosis",
        "Hamartoma Syndrome, Multiple",
        "Fragile X Syndrome",
        "Angelman Syndrome",
        "Rett Syndrome",
        "Chromosome 15Q, Partial Deletion",
        "Creatine Deficiency, X-linked"
      ],
      "interventions": [
        {
          "name": "Functional Behavioral Training (FBT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Positive Parenting Strategies-Treatment as Usual",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "2 Years to 12 Years"
      },
      "enrollment_count": 92,
      "start_date": "2023-09-15",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06139172"
    },
    {
      "nct_id": "NCT02642653",
      "title": "Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "Genetic Diseases"
      ],
      "interventions": [
        {
          "name": "Lovastatin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 30,
      "start_date": "2016-01",
      "completion_date": "2018-07",
      "has_results": true,
      "last_update_posted_date": "2019-09-11",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02642653"
    },
    {
      "nct_id": "NCT01013480",
      "title": "An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Arbaclofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seaside Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "6 Years to 40 Years"
      },
      "enrollment_count": 45,
      "start_date": "2009-11",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2012-12-20",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Sacramento, California • Chicago, Illinois + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Staten Island",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01013480"
    },
    {
      "nct_id": "NCT04308954",
      "title": "Neuroimaging GABA Physiology in Fragile X Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Fragile X Syndrome (FXS)",
        "Idiopathic Intellectual Developmental Disorder (IDD)"
      ],
      "interventions": [
        {
          "name": "[18F]flumazenil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "MALE",
        "summary": "18 Years to 30 Years · Male only"
      },
      "enrollment_count": 17,
      "start_date": "2016-11-01",
      "completion_date": "2018-12-06",
      "has_results": false,
      "last_update_posted_date": "2021-01-28",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04308954"
    },
    {
      "nct_id": "NCT03697161",
      "title": "A Study of OV101 in Individuals With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome (FXS)"
      ],
      "interventions": [
        {
          "name": "OV101 (gaboxadol)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Healx AI",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "22 Years",
        "sex": "MALE",
        "summary": "13 Years to 22 Years · Male only"
      },
      "enrollment_count": 36,
      "start_date": "2018-09-17",
      "completion_date": "2020-02-26",
      "has_results": true,
      "last_update_posted_date": "2024-01-23",
      "last_synced_at": "2026-07-22T20:14:04.285Z",
      "location_count": 6,
      "location_summary": "Sacramento, California • Aurora, Colorado • Chicago, Illinois + 3 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03697161"
    }
  ]
}