{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Facial+Expression",
    "query": {
      "condition": "Facial Expression"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Facial+Expression&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T10:46:13.677Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00275288",
      "title": "MRI Imaging in Borderline Personality Disorder",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Borderline Personality Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2005-01",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2010-11-02",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00275288"
    },
    {
      "nct_id": "NCT06778421",
      "title": "Impact of OnabotulinumtoxinA (BOTOX®) on Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Stress (Psychology)",
        "Stress",
        "Healthy Adult Female Participants",
        "Stress, Psychologic",
        "Stress, Psychological Cumulative",
        "Stress, Physiological",
        "Stress Response",
        "Stress Levels",
        "Stress Perception"
      ],
      "interventions": [
        {
          "name": "Intramuscular injection",
          "type": "PROCEDURE"
        },
        {
          "name": "OnabotulinumtoxinA (Botox®) Injections",
          "type": "DRUG"
        },
        {
          "name": "Sodium Chloride",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Center for Advanced Facial Plastic Surgery",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 4,
      "start_date": "2025-03-19",
      "completion_date": "2026-01-10",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Beverly Hills, California",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06778421"
    },
    {
      "nct_id": "NCT02106819",
      "title": "Emotional Communication Disorders in Cerebellar Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cerebellar Diseases"
      ],
      "interventions": [
        {
          "name": "Testing of emotional communication ability",
          "type": "BEHAVIORAL"
        },
        {
          "name": "magnetic resonance imaging (MRI) of the brain",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 56,
      "start_date": "2014-04",
      "completion_date": "2016-12-31",
      "has_results": false,
      "last_update_posted_date": "2017-01-31",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02106819"
    },
    {
      "nct_id": "NCT07130669",
      "title": "FACE Phase II (a Stage II Trial)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "MCI",
        "Subjective Cognitive Decline (SCD)",
        "Mild Behavioral Impairment"
      ],
      "interventions": [
        {
          "name": "Cognitive Remediation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Remediation II",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "60 Years to 89 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-10-31",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07130669"
    },
    {
      "nct_id": "NCT05343559",
      "title": "First Impressions and Attractiveness Levels of Smiling Individuals With and Without a Mask",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "First Impressions",
        "Attractiveness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "DeNova Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 808,
      "start_date": "2022-03-04",
      "completion_date": "2022-04-01",
      "has_results": false,
      "last_update_posted_date": "2022-04-25",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05343559"
    },
    {
      "nct_id": "NCT00047944",
      "title": "MRI Study of Brain Activity and Risk for Depression in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Involutional Depression",
        "Anxiety Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "10 Years to 55 Years"
      },
      "enrollment_count": 88,
      "start_date": "2002-10-12",
      "completion_date": "2016-10-27",
      "has_results": false,
      "last_update_posted_date": "2017-10-06",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00047944"
    },
    {
      "nct_id": "NCT02465307",
      "title": "Intelligent Intensive Care Unit",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Delirium",
        "Confusion"
      ],
      "interventions": [
        {
          "name": "Confusion Assessment Method",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Accelerometer",
          "type": "DEVICE"
        },
        {
          "name": "Commercially available camera",
          "type": "DEVICE"
        },
        {
          "name": "Internet Pod (iPod)",
          "type": "DEVICE"
        },
        {
          "name": "Cortisol Swab",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2016-02",
      "completion_date": "2028-05-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02465307"
    },
    {
      "nct_id": "NCT00350402",
      "title": "Masked Faces in Parkinson Disease: Mechanism and Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Respiratory muscle strength training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "45 Years to 80 Years"
      },
      "enrollment_count": 44,
      "start_date": "2004-12",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2012-04-06",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00350402"
    },
    {
      "nct_id": "NCT02923908",
      "title": "Recording Facial Expressions to Assess Taste in Children and Teenagers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Facial Expression"
      ],
      "interventions": [
        {
          "name": "Noldus Facereader 7",
          "type": "OTHER"
        },
        {
          "name": "Voice Recording",
          "type": "OTHER"
        },
        {
          "name": "5-Point Facial Hedonic Scale",
          "type": "OTHER"
        },
        {
          "name": "Follow-Up Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arkansas Children's Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "7 Years to 16 Years"
      },
      "enrollment_count": 12,
      "start_date": "2016-12",
      "completion_date": "2017-06-01",
      "has_results": false,
      "last_update_posted_date": "2018-04-10",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02923908"
    },
    {
      "nct_id": "NCT00071123",
      "title": "Evaluating Brain Responses to Facial Expressions in Major Depressive Disorder",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Current Major Depressive Disorder",
        "Healthy",
        "Remitted Major Depressive Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 172,
      "start_date": "2003-10-09",
      "completion_date": "2010-11-15",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-09-04T10:46:13.677Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00071123"
    }
  ]
}