{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Familial+Breast+Cancer",
    "query": {
      "condition": "Familial Breast Cancer"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 69,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Familial+Breast+Cancer&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:21:21.632Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05243641",
      "title": "Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Metastatic Breast Cancer",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Neratinib",
          "type": "DRUG"
        },
        {
          "name": "Capmatinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2022-08-18",
      "completion_date": "2024-11-19",
      "has_results": true,
      "last_update_posted_date": "2025-06-11",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05243641"
    },
    {
      "nct_id": "NCT00304941",
      "title": "Insulin Resistance and Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer",
        "Insulin Resistance"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 70 Years · Female only"
      },
      "enrollment_count": 25,
      "start_date": "2006-03-14",
      "completion_date": "2010-09-17",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00304941"
    },
    {
      "nct_id": "NCT01374685",
      "title": "Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ovarian Neoplasm",
        "Cancer Genetics",
        "Breast Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2011-06-07",
      "completion_date": "2016-01-07",
      "has_results": false,
      "last_update_posted_date": "2019-12-03",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01374685"
    },
    {
      "nct_id": "NCT03030404",
      "title": "Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stomach Neoplasms",
        "Stomach Cancer",
        "Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)",
        "Hereditary Diffuse Gastric Cancer (HDGC)",
        "Familial Diffuse Gastric Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 733,
      "start_date": "2017-01-27",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03030404"
    },
    {
      "nct_id": "NCT02253251",
      "title": "Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "KRAS-variant and microRNA binding site mutation testing",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "MiraKind",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15000,
      "start_date": "2014-09",
      "completion_date": "2035-09",
      "has_results": false,
      "last_update_posted_date": "2025-01-23",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02253251"
    },
    {
      "nct_id": "NCT02957981",
      "title": "The Genetic Education for Men Trial: Web-Based Education vs. Standard Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prostate Carcinoma",
        "Breast Neoplasm",
        "Pancreatic Cancer",
        "BRCA1 Mutation",
        "BRCA2 Mutation"
      ],
      "interventions": [
        {
          "name": "Web-based Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "MALE",
        "summary": "25 Years to 70 Years · Male only"
      },
      "enrollment_count": 63,
      "start_date": "2018-10-01",
      "completion_date": "2022-04-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02957981"
    },
    {
      "nct_id": "NCT02012699",
      "title": "Integrated Cancer Repository for Cancer Research",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pancreatic Cancer",
        "Thyroid Cancer",
        "Lung Cancer",
        "Esophageal Cancer",
        "Thymus Cancer",
        "Colon Cancer",
        "Rectal Cancer",
        "Gastrointestinal Stromal Tumors",
        "Anal Cancer",
        "Bile Duct Cancer",
        "Duodenal Cancer",
        "Gallbladder Cancer",
        "Gastric Cancer",
        "Liver Cancer",
        "Small Intestine Cancer",
        "Peritoneal Surface Malignancies",
        "Familial Adenomatous Polyposis",
        "Lynch Syndrome",
        "Bladder Cancer",
        "Kidney Cancer",
        "Penile Cancer",
        "Prostate Cancer",
        "Testicular Cancer",
        "Ureter Cancer",
        "Urethral Cancer",
        "Hypopharyngeal Cancer",
        "Laryngeal Cancer",
        "Lip Cancer",
        "Oral Cavity Cancer",
        "Nasopharyngeal Cancer",
        "Oropharyngeal Cancer",
        "Paranasal Sinus Cancer",
        "Nasal Cavity Cancer",
        "Salivary Gland Cancer",
        "Skin Cancer",
        "Central Nervous System Tumor",
        "Central Nervous System Cancer",
        "Mesothelioma",
        "Breast Cancer",
        "Leukemia",
        "Melanoma",
        "Sarcoma",
        "Unknown Primary Tumor",
        "Multiple Myeloma",
        "Ovarian Cancer",
        "Endometrial Cancer",
        "Vaginal Cancer",
        "Neuroendocrine Tumors",
        "Plasma Cell Dyscrasia",
        "Healthy Control"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "19 Years to 110 Years"
      },
      "enrollment_count": 999999,
      "start_date": "2013-11-01",
      "completion_date": "2099-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 42,
      "location_summary": "Greenwood Village, Colorado • Manchester, Connecticut • Daytona Beach, Florida + 34 more",
      "locations": [
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Manchester",
          "state": "Connecticut"
        },
        {
          "city": "Daytona Beach",
          "state": "Florida"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Orange City",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02012699"
    },
    {
      "nct_id": "NCT04763915",
      "title": "Improving Care After Inherited Cancer Testing",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inherited Cancer Syndrome",
        "Prostate Cancer",
        "Colorectal Cancer",
        "Endometrial Cancer",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Correlative Studies (Survey)",
          "type": "OTHER"
        },
        {
          "name": "Correlative Studies (Interview)",
          "type": "OTHER"
        },
        {
          "name": "GeneSHARE",
          "type": "BEHAVIORAL"
        },
        {
          "name": "LivingLabReport",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard-of-care & Adaptive Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Access to Education Materials",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt-Ingram Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 720,
      "start_date": "2022-08-05",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-19",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04763915"
    },
    {
      "nct_id": "NCT02667626",
      "title": "Reproductive Health Survivorship Care Plan",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Hot Flashes",
        "Sexual Dysfunction",
        "Fertility",
        "Contraception"
      ],
      "interventions": [
        {
          "name": "Reproductive Health Survivorship Care Plan (SCPR)",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 182,
      "start_date": "2015-03-25",
      "completion_date": "2019-01-24",
      "has_results": true,
      "last_update_posted_date": "2020-04-20",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02667626"
    },
    {
      "nct_id": "NCT00582803",
      "title": "Adherence to Intensive Surveillance for Hereditary Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "25 Years and older · Female only"
      },
      "enrollment_count": 85,
      "start_date": "2003-05",
      "completion_date": "2009-03",
      "has_results": false,
      "last_update_posted_date": "2009-07-10",
      "last_synced_at": "2026-05-22T04:21:21.632Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00582803"
    }
  ]
}