{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Familial+Polyposis",
    "query": {
      "condition": "Familial Polyposis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 48,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Familial+Polyposis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-21T23:12:11.513Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00641147",
      "title": "Curcumin in Treating Patients With Familial Adenomatous Polyposis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Familial Adenomatous Polyposis"
      ],
      "interventions": [
        {
          "name": "Curcumin",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 44,
      "start_date": "2010-10",
      "completion_date": "2016-11-30",
      "has_results": true,
      "last_update_posted_date": "2017-09-29",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00641147"
    },
    {
      "nct_id": "NCT03030404",
      "title": "Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stomach Neoplasms",
        "Stomach Cancer",
        "Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)",
        "Hereditary Diffuse Gastric Cancer (HDGC)",
        "Familial Diffuse Gastric Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 733,
      "start_date": "2017-01-27",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03030404"
    },
    {
      "nct_id": "NCT00151476",
      "title": "Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Familial Adenomatous Polyposis (FAP)"
      ],
      "interventions": [
        {
          "name": "Celecoxib",
          "type": "DRUG"
        },
        {
          "name": "Routine Medical Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2004-11",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2024-09-04",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00151476"
    },
    {
      "nct_id": "NCT00503035",
      "title": "Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Familial Adenomatous Polyposis"
      ],
      "interventions": [
        {
          "name": "Celecoxib",
          "type": "DRUG"
        },
        {
          "name": "Colonoscopy Biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2003-08-20",
      "completion_date": "2021-04-02",
      "has_results": true,
      "last_update_posted_date": "2023-02-13",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00503035"
    },
    {
      "nct_id": "NCT02747862",
      "title": "Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Attenuated Familial Adenomatous Polyposis",
        "Deleterious Familial Adenomatous Polyposis"
      ],
      "interventions": [
        {
          "name": "Chart Review",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1500,
      "start_date": "2008-02",
      "completion_date": "2022-08-17",
      "has_results": false,
      "last_update_posted_date": "2022-09-02",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02747862"
    },
    {
      "nct_id": "NCT05552755",
      "title": "Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Familial Adenomatous Polyposis"
      ],
      "interventions": [
        {
          "name": "REC-4881",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Recursion Pharmaceuticals Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2023-07-10",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 17,
      "location_summary": "Scottsdale, Arizona • Tucson, Arizona • San Diego, California + 14 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Naples",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05552755"
    },
    {
      "nct_id": "NCT05692596",
      "title": "The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pancreatic Ductal Adenocarcinoma",
        "Pancreatic Cyst",
        "Chronic Pancreatitis",
        "Fatty Pancreas",
        "Genetic Pancreatic Cancer",
        "Genetic Pancreatitis",
        "BRCA Mutation",
        "Lynch Syndrome",
        "FAP",
        "Familial Atypical Multiple Mole-Melanoma",
        "PALB2 Gene Mutation",
        "Peutz-Jeghers Syndrome",
        "Ataxia Telangiectasia"
      ],
      "interventions": [
        {
          "name": "Data collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 317,
      "start_date": "2022-10-06",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05692596"
    },
    {
      "nct_id": "NCT04230499",
      "title": "Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Familial Adenomatous Polyposis"
      ],
      "interventions": [
        {
          "name": "Encapsulated Rapamycin (eRapa)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rapamycin Holdings Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2021-01-18",
      "completion_date": "2025-03",
      "has_results": false,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 4,
      "location_summary": "Ann Arbor, Michigan • Cleveland, Ohio • Columbus, Ohio + 1 more",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04230499"
    },
    {
      "nct_id": "NCT03050268",
      "title": "Familial Investigations of Childhood Cancer Predisposition",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Leukemia",
        "Adenomatous Polyposis",
        "Adrenocortical Carcinoma",
        "AML",
        "BAP1 Tumor Predisposition Syndrome",
        "Carney Complex",
        "Choroid Plexus Carcinoma",
        "Constitutional Mismatch Repair Deficiency Syndrome",
        "Diamond-Blackfan Anemia",
        "DICER1 Syndrome",
        "Dyskeratosis Congenita",
        "Emberger Syndrome",
        "Familial Acute Myeloid Leukemia",
        "Familial Adenomatous Polyposis",
        "Fanconi Anemia",
        "Familial Cancer",
        "Familial Wilms Tumor",
        "Familial Neuroblastoma",
        "GIST",
        "Hereditary Breast and Ovarian Cancer",
        "Hereditary Paraganglioma-Pheochromocytoma Syndrome",
        "Hodgkin Lymphoma",
        "Juvenile Polyposis",
        "Li-Fraumeni Syndrome",
        "Lynch Syndrome",
        "MDS",
        "Melanoma Syndrome",
        "Multiple Endocrine Neoplasia Type 1",
        "Multiple Endocrine Neoplasia Type 2",
        "Neuroblastoma",
        "Neurofibromatosis Type 1",
        "Neurofibromatosis Type II",
        "Nevoid Basal Cell Carcinoma Syndrome",
        "Non Hodgkin Lymphoma",
        "Noonan Syndrome and Other Rasopathy",
        "Overgrowth Syndromes",
        "Pancreatic Cancer",
        "Peutz-Jeghers Syndrome",
        "Pheochromocytoma/Paraganglioma",
        "PTEN Hamartoma Tumor Syndrome",
        "Retinoblastoma",
        "Rhabdoid Tumor Predisposition Syndrome",
        "Rhabdomyosarcoma",
        "Rothmund-Thomson Syndrome",
        "Tuberous Sclerosis",
        "Von Hippel-Lindau Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1500,
      "start_date": "2017-04-06",
      "completion_date": "2037-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03050268"
    },
    {
      "nct_id": "NCT05014360",
      "title": "A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Adenomatous Polyposis Coli"
      ],
      "interventions": [
        {
          "name": "JNJ-64251330",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Janssen Research & Development, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2021-11-10",
      "completion_date": "2023-02-15",
      "has_results": false,
      "last_update_posted_date": "2023-06-02",
      "last_synced_at": "2026-07-21T23:12:11.513Z",
      "location_count": 5,
      "location_summary": "Duarte, California • Miami, Florida • Boston, Massachusetts + 1 more",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05014360"
    }
  ]
}