{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fatigability&page=2",
    "query": {
      "condition": "Fatigability",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fatigability&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T19:01:36.978Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04321304",
      "title": "Impact of Transcranial Direct Current Stimulation Intensity on Leg Muscle Fatigability in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Sham transcranial direct current stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Transcranial direct current stimulation at 2 mA",
          "type": "DEVICE"
        },
        {
          "name": "Transcranial direct current stimulation at 4 mA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 35,
      "start_date": "2019-05-01",
      "completion_date": "2019-09-01",
      "has_results": false,
      "last_update_posted_date": "2021-07-08",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04321304"
    },
    {
      "nct_id": "NCT03735654",
      "title": "Multi-joint Muscle Fatigability and Gait Performance in People With Multiple Sclerosis",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Multiple Sclerosis",
        "Gait Disorders, Neurologic",
        "Fatigue"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington D.C. Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 35,
      "start_date": "2018-11-15",
      "completion_date": "2021-10-01",
      "has_results": false,
      "last_update_posted_date": "2018-11-08",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03735654"
    },
    {
      "nct_id": "NCT04706299",
      "title": "Effects of Surgical Mask Use on Peak Torque, Total Work and Interset Fatigability During Isokinetic Strength Testing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prevention of COVID-19"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-01-12",
      "completion_date": "2021-05-21",
      "has_results": false,
      "last_update_posted_date": "2021-05-24",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Garfield Heights, Ohio",
      "locations": [
        {
          "city": "Garfield Heights",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04706299"
    },
    {
      "nct_id": "NCT03065959",
      "title": "A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Mobility Limitation"
      ],
      "interventions": [
        {
          "name": "reldesemtiv",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Astellas Pharma Global Development, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "65 Years to 89 Years"
      },
      "enrollment_count": 42,
      "start_date": "2017-06-28",
      "completion_date": "2018-10-10",
      "has_results": false,
      "last_update_posted_date": "2024-10-31",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 5,
      "location_summary": "Gainesville, Florida • Boston, Massachusetts • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Athens",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03065959"
    },
    {
      "nct_id": "NCT05558501",
      "title": "Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Mild Intermittent Hypoxia",
          "type": "OTHER"
        },
        {
          "name": "Sham MIH",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-01-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-04",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05558501"
    },
    {
      "nct_id": "NCT03888040",
      "title": "Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Marquette University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 120,
      "start_date": "2020-09-01",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-11",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03888040"
    },
    {
      "nct_id": "NCT03800342",
      "title": "Recovery, Fatigability, and Proteomic Response to Aerobic Exercise Training in Healthy Individuals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adult",
        "Fatigue"
      ],
      "interventions": [
        {
          "name": "Aerobic Exercise Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "George Mason University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 21,
      "start_date": "2019-01-22",
      "completion_date": "2019-04-24",
      "has_results": false,
      "last_update_posted_date": "2019-05-16",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Fairfax, Virginia",
      "locations": [
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03800342"
    },
    {
      "nct_id": "NCT04442451",
      "title": "Mechanisms of Fatigability With Diabetes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pre-diabetes",
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Control Exercise",
          "type": "OTHER"
        },
        {
          "name": "Blood Flow Restriction Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "30 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-09-01",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-08",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04442451"
    },
    {
      "nct_id": "NCT01661595",
      "title": "The Effect of Sildenafil and Tadalafil on Skeletal Muscle and Perceptual Fatigue",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fatigue"
      ],
      "interventions": [
        {
          "name": "Sildenafil",
          "type": "DRUG"
        },
        {
          "name": "tadalafil",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "50 Years to 60 Years"
      },
      "enrollment_count": 30,
      "start_date": "2012-11",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2018-07-17",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01661595"
    },
    {
      "nct_id": "NCT05618574",
      "title": "Nitrite Supplementation in Long COVID Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Long COVID",
        "Cardiorespiratory Fitness"
      ],
      "interventions": [
        {
          "name": "140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "210 ml of nitrate-depleted placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2023-12-01",
      "completion_date": "2025-02-14",
      "has_results": false,
      "last_update_posted_date": "2025-03-19",
      "last_synced_at": "2026-07-22T19:01:36.978Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05618574"
    }
  ]
}