{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fibrinolysis",
    "query": {
      "condition": "Fibrinolysis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 41,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fibrinolysis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T00:04:54.432Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02901067",
      "title": "STAT-STatin and Aspirin in Trauma",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Wounds and Injuries",
        "Venous Thromboembolism"
      ],
      "interventions": [
        {
          "name": "Aspirin and Rosuvastatin",
          "type": "DRUG"
        },
        {
          "name": "Placebo (for Aspirin and Rosuvastatin)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Denver Health and Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 43,
      "start_date": "2017-02-03",
      "completion_date": "2021-08-01",
      "has_results": true,
      "last_update_posted_date": "2023-04-27",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02901067"
    },
    {
      "nct_id": "NCT00685945",
      "title": "Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Control (bradykinin)",
          "type": "DRUG"
        },
        {
          "name": "L-NMMA + bradykinin",
          "type": "DRUG"
        },
        {
          "name": "Isosorbide + L-NMMA + bradykinin",
          "type": "DRUG"
        },
        {
          "name": "Sildenafil + L-NMMA + bradykinin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2007-12",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2013-02-25",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00685945"
    },
    {
      "nct_id": "NCT00607672",
      "title": "The RAS, Fibrinolysis and Cardiopulmonary Bypass",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Angiotensin Converting Enzyme",
        "Angiotensin Receptor Blockers",
        "Cardiopulmonary Bypass",
        "Fibrinolysis",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ramipril",
          "type": "DRUG"
        },
        {
          "name": "Candesartan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 111,
      "start_date": "2006-08",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2012-10-10",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 2,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00607672"
    },
    {
      "nct_id": "NCT01862458",
      "title": "Empyema Treated With tPA & DNAse",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Empyema"
      ],
      "interventions": [
        {
          "name": "tPA alone",
          "type": "BIOLOGICAL"
        },
        {
          "name": "tPA plus dornase",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2016-01",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-01-28",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01862458"
    },
    {
      "nct_id": "NCT00780637",
      "title": "Brachial Artery t-PA Release in Heart Transplant Recipients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Transplantation"
      ],
      "interventions": [
        {
          "name": "Bradykinin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2008-10",
      "completion_date": "2011-05",
      "has_results": false,
      "last_update_posted_date": "2016-07-15",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00780637"
    },
    {
      "nct_id": "NCT02973139",
      "title": "Fibrinolysis Compared to Thoracoscopy for Pleural Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pleural Infection",
        "Pleural Diseases"
      ],
      "interventions": [
        {
          "name": "Medical Thoracoscopy",
          "type": "OTHER"
        },
        {
          "name": "Fibrinolytic Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2017-07-14",
      "completion_date": "2019-11-01",
      "has_results": false,
      "last_update_posted_date": "2019-12-26",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02973139"
    },
    {
      "nct_id": "NCT05387577",
      "title": "Coagulation and Fibrinolysis of Estradiol in Transwomen",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Transgenderism",
        "Clotting Disorder"
      ],
      "interventions": [
        {
          "name": "Estradiol Tablets",
          "type": "DRUG"
        },
        {
          "name": "Transdermal patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 6,
      "start_date": "2021-12-07",
      "completion_date": "2022-11-23",
      "has_results": false,
      "last_update_posted_date": "2022-12-21",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05387577"
    },
    {
      "nct_id": "NCT02352675",
      "title": "Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease",
        "Fibrinolysis",
        "Rotational Thromboelastometry"
      ],
      "interventions": [
        {
          "name": "Intraoperative Blood Sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "2 Months to 12 Months"
      },
      "enrollment_count": 40,
      "start_date": "2015-04",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2017-08-01",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02352675"
    },
    {
      "nct_id": "NCT07227740",
      "title": "Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Cord Injuries",
        "Endothelial Dysfunction",
        "Testosterone Deficiency"
      ],
      "interventions": [
        {
          "name": "Intra-arterial Infusion of Vasoactive Agents",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Intra-arterial Vitamin C Infusion",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Sampling",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Craig Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "MALE",
        "summary": "18 Years to 89 Years · Male only"
      },
      "enrollment_count": 48,
      "start_date": "2025-07-15",
      "completion_date": "2028-07-14",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07227740"
    },
    {
      "nct_id": "NCT01513759",
      "title": "Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pulmonary Embolism",
        "Acute Pulmonary Embolism",
        "Sub-massive Pulmonary Embolism",
        "Massive Pulmonary Embolism",
        "Pulmonary Thromboembolism"
      ],
      "interventions": [
        {
          "name": "recombinant tissue plasminogen activator",
          "type": "DRUG"
        },
        {
          "name": "EKOS EkoSonic Endovascular System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2012-06-07",
      "completion_date": "2013-02-17",
      "has_results": true,
      "last_update_posted_date": "2021-07-19",
      "last_synced_at": "2026-05-22T00:04:54.432Z",
      "location_count": 22,
      "location_summary": "Montgomery, Alabama • Modesto, California • Stanford, California + 18 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Modesto",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01513759"
    }
  ]
}