{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fibrous+Dysplasia%2FMcCune-Albright+Syndrome", "query": { "condition": "Fibrous Dysplasia/McCune-Albright Syndrome" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 14, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fibrous+Dysplasia%2FMcCune-Albright+Syndrome&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-10T09:26:44.873Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00017927", "title": "A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "McCune Albright Syndrome", "Polyostotic Fibrous Dysplasia" ], "interventions": [ { "name": "Pegvisomant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 10, "start_date": "2001-06", "completion_date": "2005-06", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00017927" }, { "nct_id": "NCT03231644", "title": "Fibrous Dysplasia, McCune-Albright Syndrome Patient Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Fibrous Dysplasia", "McCune Albright Syndrome", "Mazabraud Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Tovah Burstein", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 600, "start_date": "2016-10-31", "completion_date": "2028-10", "has_results": false, "last_update_posted_date": "2025-08-12", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03231644" }, { "nct_id": "NCT00001728", "title": "Alendronate to Treat Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Polyostotic Fibrous Dysplasia" ], "interventions": [ { "name": "Fosamax (Alendronate)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 40, "start_date": "1998-08-24", "completion_date": "2011-05-02", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001728" }, { "nct_id": "NCT04125862", "title": "Pain in Fibrous Dysplasia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Fibrous Dysplasia/McCune-Albright Syndrome" ], "interventions": [ { "name": "MRI-based Neuroimaging", "type": "DIAGNOSTIC_TEST" }, { "name": "Non-contrast MRI", "type": "DIAGNOSTIC_TEST" }, { "name": "18F-FDG-PET/CT", "type": "DIAGNOSTIC_TEST" }, { "name": "18F-NaF-PET/CT", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "10 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "10 Years to 45 Years" }, "enrollment_count": 37, "start_date": "2021-01-05", "completion_date": "2025-12-01", "has_results": false, "last_update_posted_date": "2025-12-11", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04125862" }, { "nct_id": "NCT00001727", "title": "Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "McCune-Albright Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "100 Years", "sex": "ALL", "summary": "1 Day to 100 Years" }, "enrollment_count": 500, "start_date": "1998-12-13", "completion_date": null, "has_results": false, "last_update_posted_date": "2026-06-08", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001727" }, { "nct_id": "NCT00318097", "title": "Histamine Responsiveness in McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "McCune-Albright Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Mercy Hospital Kansas City", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "39 Years", "sex": "ALL", "summary": "Up to 39 Years" }, "enrollment_count": 22, "start_date": "2004-08-01", "completion_date": "2007-08-01", "has_results": false, "last_update_posted_date": "2018-02-06", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00318097" }, { "nct_id": "NCT05509595", "title": "Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Fibrous Dysplasia Of Bone" ], "interventions": [ { "name": "Burosumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "99 Years", "sex": "ALL", "summary": "1 Year to 99 Years" }, "enrollment_count": 12, "start_date": "2022-12-07", "completion_date": "2024-11-18", "has_results": true, "last_update_posted_date": "2026-02-02", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05509595" }, { "nct_id": "NCT00006174", "title": "Effects of Letrozole on Precocious Puberty Due to McCune Albright Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "McCune Albright Syndrome", "Polyostotic Fibrous Dysplasia", "Precocious Puberty" ], "interventions": [ { "name": "Letrozole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "8 Years", "sex": "FEMALE", "summary": "1 Year to 8 Years · Female only" }, "enrollment_count": 25, "start_date": "2000-08-03", "completion_date": "2009-05-18", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00006174" }, { "nct_id": "NCT00001181", "title": "Testolactone for the Treatment of Girls With LHRH Resistant Precocious Puberty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Polyostotic Fibrous Dysplasia", "Precocious Puberty" ], "interventions": [ { "name": "Testolactone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 100, "start_date": "1982-10", "completion_date": "2003-05", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001181" }, { "nct_id": "NCT00001851", "title": "Bone Marrow Injection to Replace Diseased Bone in Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Polyostotic Fibrous Dysplasia" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": null, "sex": "ALL", "summary": "4 Years and older" }, "enrollment_count": 50, "start_date": "1998-12-15", "completion_date": "2002-04-30", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-06-10T09:26:44.873Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001851" } ] }