{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Flow+Mediated+Dilation",
    "query": {
      "condition": "Flow Mediated Dilation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 50,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Flow+Mediated+Dilation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T07:04:17.923Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07109739",
      "title": "Dose-Response Effects of Inspiratory Muscle Strength Training on Blood Pressure and Vascular Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Systolic Hypertension",
        "Brachial Artery Flow-mediated Dilation"
      ],
      "interventions": [
        {
          "name": "POWERbreathe K5",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2025-10-24",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07109739"
    },
    {
      "nct_id": "NCT05221905",
      "title": "Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Vascular Dilation",
        "Arterial Stiffness"
      ],
      "interventions": [
        {
          "name": "BEET IT - Concentrate Beet root juice",
          "type": "DRUG"
        },
        {
          "name": "BEET IT - Concentrate Beet root juice (nitrate depleted)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 75 Years · Female only"
      },
      "enrollment_count": 24,
      "start_date": "2021-11-01",
      "completion_date": "2023-04-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-30",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05221905"
    },
    {
      "nct_id": "NCT01398943",
      "title": "Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive"
      ],
      "interventions": [
        {
          "name": "Tetrahydrobiopterin (BH4)",
          "type": "DRUG"
        },
        {
          "name": "Antioxidant Cocktail",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2010-09",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-12-11",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01398943"
    },
    {
      "nct_id": "NCT01911169",
      "title": "Vitamin D to Improve Endothelial Function in SLE",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Atherosclerosis",
        "Systemic Lupus Erythematosus"
      ],
      "interventions": [
        {
          "name": "Cholecalciferol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 9,
      "start_date": "2011-06",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2017-10-27",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01911169"
    },
    {
      "nct_id": "NCT01964807",
      "title": "Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter"
      ],
      "interventions": [
        {
          "name": "Cigarette, NIDA test type with 16.6 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "Cigarette, NIDA test type with <0.45 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarette with 18 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Electronic Cigarette with no nicotine",
          "type": "OTHER"
        },
        {
          "name": "Moist snuff",
          "type": "OTHER"
        },
        {
          "name": "Sham Smoking",
          "type": "OTHER"
        },
        {
          "name": "Secondhand cigarette smoke (SHS)",
          "type": "OTHER"
        },
        {
          "name": "Conditioned, filtered air",
          "type": "OTHER"
        },
        {
          "name": "Sham Moist Snuff",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 81,
      "start_date": "2013-11-03",
      "completion_date": "2021-05-31",
      "has_results": false,
      "last_update_posted_date": "2021-12-27",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01964807"
    },
    {
      "nct_id": "NCT02682576",
      "title": "Brachial Artery Ultrasound Imaging: A Repeatability Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Brachial artery ultrasound imaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Everist Genomics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2016-04",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2017-02-08",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 2,
      "location_summary": "Derby, Connecticut • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Derby",
          "state": "Connecticut"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02682576"
    },
    {
      "nct_id": "NCT01502787",
      "title": "Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Metoprolol succinate",
          "type": "DRUG"
        },
        {
          "name": "Nebivolol",
          "type": "DRUG"
        },
        {
          "name": "Forearm blood flow",
          "type": "PROCEDURE"
        },
        {
          "name": "Microneurography",
          "type": "PROCEDURE"
        },
        {
          "name": "Rhythmic handgrip exercise",
          "type": "PROCEDURE"
        },
        {
          "name": "Lower body negative pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "Angiotensin II",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 46,
      "start_date": "2009-04",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2020-07-07",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01502787"
    },
    {
      "nct_id": "NCT00924157",
      "title": "Effect of Ile-Pro-Pro (IPP) on Endothelial Function in Patients With Coronary Artery Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "IPP",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 54,
      "start_date": "2009-07",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2012-05-25",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00924157"
    },
    {
      "nct_id": "NCT03486145",
      "title": "Effect of Nitrate-rich Fruit and Vegetable Supplement on Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "High Blood Pressure",
        "Flow Mediated Dilation"
      ],
      "interventions": [
        {
          "name": "fruit and vegetable juice supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 57,
      "start_date": "2015-11-16",
      "completion_date": "2016-03-30",
      "has_results": false,
      "last_update_posted_date": "2018-04-03",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03486145"
    },
    {
      "nct_id": "NCT02414204",
      "title": "Phosphodiesterase Type 5 Inhibition to Improve Endothelial Function and Vascular Remodeling in Chronic Kidney Disease and End Stage Renal Disease Patients Requiring New Arteriovenous Fistula",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Improve Endothelial Function and Decrease Vascular Stenosis"
      ],
      "interventions": [
        {
          "name": "Sildenafil",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "19 Years to 99 Years"
      },
      "enrollment_count": 4,
      "start_date": "2015-04",
      "completion_date": "2018-06-30",
      "has_results": true,
      "last_update_posted_date": "2019-08-12",
      "last_synced_at": "2026-07-24T07:04:17.923Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02414204"
    }
  ]
}