{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fluid+Imbalance&page=2",
    "query": {
      "condition": "Fluid Imbalance",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fluid+Imbalance&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T11:59:59.333Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03924674",
      "title": "SOFI: A Quality Improvement Project to Standardize Use of Intravenous Fluids in Hospitalized Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intravenous Fluids",
        "Fluid and Electrolyte Imbalance",
        "ADH Inappropriate"
      ],
      "interventions": [
        {
          "name": "Education, clinical decision support tools",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "28 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "28 Days to 18 Years"
      },
      "enrollment_count": 106,
      "start_date": "2019-04-01",
      "completion_date": "2020-05-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-29",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 89,
      "location_summary": "Phoenix, Arizona • Fresno, California • Loma Linda, California + 76 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03924674"
    },
    {
      "nct_id": "NCT02524002",
      "title": "Enhanced vs. Routine Clear Liquid Intake in Labor",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abnormal Labor",
        "Failed Induction of Labor",
        "Ketosis"
      ],
      "interventions": [
        {
          "name": "Accel Gel",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Usual clear diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Temple University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 76,
      "start_date": "2014-08",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2018-06-12",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02524002"
    },
    {
      "nct_id": "NCT01227512",
      "title": "Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hyponatremia",
        "Dilutional Hyponatremia",
        "Inappropriate ADH Syndrome"
      ],
      "interventions": [
        {
          "name": "tolvaptan",
          "type": "DRUG"
        },
        {
          "name": "Fluid Restriction",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2010-10",
      "completion_date": "2013-05",
      "has_results": true,
      "last_update_posted_date": "2014-10-30",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 56,
      "location_summary": "Birmingham, Alabama • Mobile, Alabama • Azusa, California + 46 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Azusa",
          "state": "California"
        },
        {
          "city": "Banning",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01227512"
    },
    {
      "nct_id": "NCT03636568",
      "title": "Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyponatremia",
        "Hyponatremic",
        "Pituitary Tumor",
        "Pituitary",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Fluid Restricted Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2016-06-02",
      "completion_date": "2024-07-22",
      "has_results": false,
      "last_update_posted_date": "2024-07-23",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03636568"
    },
    {
      "nct_id": "NCT06366230",
      "title": "Adding Urea to the Final Dialysis Fluid",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Dysequilibrium Syndrome",
        "ESRD",
        "Hyperkalemia",
        "Metabolic Acidosis"
      ],
      "interventions": [
        {
          "name": "Urea in the dialysate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-09-16",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06366230"
    },
    {
      "nct_id": "NCT06995144",
      "title": "Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure",
        "Edema",
        "Pulmonary Congestion",
        "Fluid Overload"
      ],
      "interventions": [
        {
          "name": "Extended Release Torsemide Tablets",
          "type": "DRUG"
        },
        {
          "name": "Immedate Release Torsemide Tablets",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sarfez Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-05-28",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06995144"
    },
    {
      "nct_id": "NCT05768789",
      "title": "Buoy Electrolyte Study on Hydration Status of Active Men and Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration",
        "Electrolyte Imbalance",
        "Electrolyte Depletion",
        "Fluid and Electrolyte Imbalance"
      ],
      "interventions": [
        {
          "name": "Buoy Electrolyte",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Water only",
          "type": "OTHER"
        },
        {
          "name": "Nuun Electrolyte",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-09-13",
      "completion_date": "2024-04-27",
      "has_results": true,
      "last_update_posted_date": "2025-05-14",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05768789"
    },
    {
      "nct_id": "NCT02667977",
      "title": "Reexamining Hypotonic Intravenous Fluid Use",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyponatremia"
      ],
      "interventions": [
        {
          "name": "0.9 Normal Saline",
          "type": "OTHER"
        },
        {
          "name": "0.45 Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "6 Months to 16 Years"
      },
      "enrollment_count": 0,
      "start_date": "2014-10",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-01-29",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02667977"
    },
    {
      "nct_id": "NCT06858904",
      "title": "Rehydration With a Trace Mineral Supplement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration (Physiology)"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "ConcenTrace",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "ZeroLyte",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-03-26",
      "completion_date": "2025-08-29",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06858904"
    },
    {
      "nct_id": "NCT01270854",
      "title": "Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wounds and Injuries",
        "Multiple Trauma",
        "Disorder of Fluid Balance"
      ],
      "interventions": [
        {
          "name": "Plasmalyte A",
          "type": "OTHER"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2011-02",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-07-23T11:59:59.333Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01270854"
    }
  ]
}