{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fluid+and+Electrolyte+Imbalance",
    "query": {
      "condition": "Fluid and Electrolyte Imbalance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fluid+and+Electrolyte+Imbalance&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:48:47.171Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02052284",
      "title": "The Application of Sterile Water to the Skin of Extremely Low Birth Weight (ELBW) Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fluid Loss",
        "Dehydration",
        "Extreme Immaturity"
      ],
      "interventions": [
        {
          "name": "Sterile water application",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 30,
      "start_date": "2014-01",
      "completion_date": "2017-12-31",
      "has_results": false,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02052284"
    },
    {
      "nct_id": "NCT05285371",
      "title": "Boluses of Ringer's in Surgical Kids (BRiSK Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Dehydration in Children",
        "Fluid Therapy"
      ],
      "interventions": [
        {
          "name": "Urinalysis (UA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Complete Metabolic Panel (CMP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Glucose Stick Test (d-Stick)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Medical Chart Review",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "1 Year to 21 Years"
      },
      "enrollment_count": 70,
      "start_date": "2022-02-22",
      "completion_date": "2024-08-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05285371"
    },
    {
      "nct_id": "NCT05768789",
      "title": "Buoy Electrolyte Study on Hydration Status of Active Men and Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration",
        "Electrolyte Imbalance",
        "Electrolyte Depletion",
        "Fluid and Electrolyte Imbalance"
      ],
      "interventions": [
        {
          "name": "Buoy Electrolyte",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Water only",
          "type": "OTHER"
        },
        {
          "name": "Nuun Electrolyte",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-09-13",
      "completion_date": "2024-04-27",
      "has_results": true,
      "last_update_posted_date": "2025-05-14",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05768789"
    },
    {
      "nct_id": "NCT00807885",
      "title": "Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dehydration"
      ],
      "interventions": [
        {
          "name": "hylenex-facilitated subcutaneous Lactated Ringer's infusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baxter Healthcare Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 100,
      "start_date": "2008-12",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2011-10-26",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 2,
      "location_summary": "Lincoln, Nebraska • Neptune City, New Jersey",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        },
        {
          "city": "Neptune City",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00807885"
    },
    {
      "nct_id": "NCT03924674",
      "title": "SOFI: A Quality Improvement Project to Standardize Use of Intravenous Fluids in Hospitalized Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intravenous Fluids",
        "Fluid and Electrolyte Imbalance",
        "ADH Inappropriate"
      ],
      "interventions": [
        {
          "name": "Education, clinical decision support tools",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "28 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "28 Days to 18 Years"
      },
      "enrollment_count": 106,
      "start_date": "2019-04-01",
      "completion_date": "2020-05-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-29",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 89,
      "location_summary": "Phoenix, Arizona • Fresno, California • Loma Linda, California + 76 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03924674"
    },
    {
      "nct_id": "NCT06366230",
      "title": "Adding Urea to the Final Dialysis Fluid",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Dysequilibrium Syndrome",
        "ESRD",
        "Hyperkalemia",
        "Metabolic Acidosis"
      ],
      "interventions": [
        {
          "name": "Urea in the dialysate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-09-16",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06366230"
    },
    {
      "nct_id": "NCT01056848",
      "title": "International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hyponatremia With Normal Extracellular Fluid Volume",
        "Hyponatremia With Excess Extracellular Fluid Volume"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "CardioKine Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2010-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-06-21",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 6,
      "location_summary": "Lomita, California • Clearewater, Florida • Fleming Island, Florida + 3 more",
      "locations": [
        {
          "city": "Lomita",
          "state": "California"
        },
        {
          "city": "Clearewater",
          "state": "Florida"
        },
        {
          "city": "Fleming Island",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Creve Cour",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01056848"
    },
    {
      "nct_id": "NCT03799380",
      "title": "DRIHNC - Dehydration Reduction in Head & Neck Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration",
        "Head & Neck Cancer",
        "Esophageal Cancer"
      ],
      "interventions": [
        {
          "name": "Gatorade G2",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Standard of care nutritional support",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2019-11-05",
      "completion_date": "2021-05-05",
      "has_results": false,
      "last_update_posted_date": "2021-11-03",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03799380"
    },
    {
      "nct_id": "NCT06858904",
      "title": "Rehydration With a Trace Mineral Supplement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration (Physiology)"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "ConcenTrace",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "ZeroLyte",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-03-26",
      "completion_date": "2025-08-29",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06858904"
    },
    {
      "nct_id": "NCT00578695",
      "title": "THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hyponatremia"
      ],
      "interventions": [
        {
          "name": "lixivaptan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "CardioKine Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 652,
      "start_date": "2007-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-06-28",
      "last_synced_at": "2026-05-22T06:48:47.171Z",
      "location_count": 102,
      "location_summary": "Birmingham, Alabama • Mobile, Alabama • Bakersfield, California + 82 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Banning",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00578695"
    }
  ]
}