{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fontan&page=2",
    "query": {
      "condition": "Fontan",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fontan&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:07:33.547Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04867954",
      "title": "Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cirrhosis, Liver",
        "Gastroesophageal Varices",
        "Fontan Procedure"
      ],
      "interventions": [
        {
          "name": "Ensure Plus®",
          "type": "OTHER"
        },
        {
          "name": "Pre-clinical validation contrast enhanced MRI",
          "type": "OTHER"
        },
        {
          "name": "Clinical validation MRI",
          "type": "OTHER"
        },
        {
          "name": "Pre-clinical validation contrast enhanced MRI + fasting",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 146,
      "start_date": "2021-10-28",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04867954"
    },
    {
      "nct_id": "NCT02946892",
      "title": "Effect of Carvedilol on Exercise Performance in Fontan Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Single Ventricle",
        "Fontan"
      ],
      "interventions": [
        {
          "name": "Carvedilol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "10 Years to 35 Years"
      },
      "enrollment_count": 26,
      "start_date": "2016-11",
      "completion_date": "2020-01",
      "has_results": true,
      "last_update_posted_date": "2021-01-22",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02946892"
    },
    {
      "nct_id": "NCT03470428",
      "title": "Clinical Characteristics and Associations of the \"Good Fontan\" Patient",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease",
        "Single-ventricle"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "10 Years to 60 Years"
      },
      "enrollment_count": 146,
      "start_date": "2018-03-05",
      "completion_date": "2023-04-18",
      "has_results": false,
      "last_update_posted_date": "2023-04-19",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03470428"
    },
    {
      "nct_id": "NCT03726229",
      "title": "Cholate Clearance in Fontans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fontan Procedure"
      ],
      "interventions": [
        {
          "name": "Cholate assay",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2019-05-01",
      "completion_date": "2022-05-25",
      "has_results": false,
      "last_update_posted_date": "2022-06-10",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03726229"
    },
    {
      "nct_id": "NCT01149603",
      "title": "The Destination Therapy Evaluation for Failing Fontan Study",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Failing Fontan Physiology",
        "Failing Fontan",
        "Single-ventricle",
        "Single-ventricle Fontan",
        "Single-ventricle Physiology"
      ],
      "interventions": [
        {
          "name": "HeartMate II Ventricular Assist Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Timothy Icenogle, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2010-07",
      "completion_date": "2017-09-19",
      "has_results": false,
      "last_update_posted_date": "2017-09-21",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Spokane, Washington",
      "locations": [
        {
          "city": "Spokane",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01149603"
    },
    {
      "nct_id": "NCT00945529",
      "title": "The Effects of Inhaled Nitric Oxide After Fontan Operation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Congenital Heart Defect"
      ],
      "interventions": [
        {
          "name": "inhaled nitric oxide (iNO)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ellen Spurrier",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "1 Year to 5 Years"
      },
      "enrollment_count": 21,
      "start_date": "2008-02",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00945529"
    },
    {
      "nct_id": "NCT03088345",
      "title": "Early Use of Vasopressin in Post-Fontan Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Circulatory Perfusion Disorder",
        "Congenital Heart Disease",
        "Single-ventricle"
      ],
      "interventions": [
        {
          "name": "Vasopressin, Arginine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Weeks",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Weeks to 18 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-03-06",
      "completion_date": "2019-01-28",
      "has_results": true,
      "last_update_posted_date": "2020-07-07",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03088345"
    },
    {
      "nct_id": "NCT03153137",
      "title": "Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Macitentan 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Actelion",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 142,
      "start_date": "2017-08-14",
      "completion_date": "2021-07-26",
      "has_results": true,
      "last_update_posted_date": "2025-03-30",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 6,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Boston, Massachusetts + 3 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03153137"
    },
    {
      "nct_id": "NCT00211081",
      "title": "Spironolactone in Patients With Single Ventricle Heart",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Disorders"
      ],
      "interventions": [
        {
          "name": "Spironolactone (drug)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2004-11",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00211081"
    },
    {
      "nct_id": "NCT00974025",
      "title": "Impact of Vitamin C on Endothelial Function and Exercise Capacity in Fontan-Palliated Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fontan Procedure",
        "Hypoplastic Left Heart Syndrome",
        "Tricuspid Atresia"
      ],
      "interventions": [
        {
          "name": "Vitamin C",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "8 Years to 25 Years"
      },
      "enrollment_count": 53,
      "start_date": "2009-06",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2017-06-01",
      "last_synced_at": "2026-05-22T03:07:33.547Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00974025"
    }
  ]
}