{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fra%28X%29+Syndrome",
    "query": {
      "condition": "Fra(X) Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T06:11:37.216Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02642653",
      "title": "Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "Genetic Diseases"
      ],
      "interventions": [
        {
          "name": "Lovastatin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 30,
      "start_date": "2016-01",
      "completion_date": "2018-07",
      "has_results": true,
      "last_update_posted_date": "2019-09-11",
      "last_synced_at": "2026-07-23T06:11:37.216Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02642653"
    },
    {
      "nct_id": "NCT03479476",
      "title": "A Trial of Metformin in Individuals With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "Fragile X Mental Retardation Syndrome",
        "Mental Retardation, X Linked",
        "Genetic Diseases, X-Linked",
        "Trinucleotide Repeat Expansion",
        "Fra(X) Syndrome",
        "Intellectual Disability",
        "FXS",
        "Neurobehavioral Manifestations",
        "Sex Chromosome Disorders"
      ],
      "interventions": [
        {
          "name": "Placebo Medication",
          "type": "DRUG"
        },
        {
          "name": "Metformin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "6 Years to 25 Years"
      },
      "enrollment_count": 120,
      "start_date": "2018-04-30",
      "completion_date": "2024-05-22",
      "has_results": false,
      "last_update_posted_date": "2025-01-17",
      "last_synced_at": "2026-07-23T06:11:37.216Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03479476"
    },
    {
      "nct_id": "NCT04869930",
      "title": "Establishing a Diagnostic and Therapeutic Index in Autism Spectrum Disorder (ASD) and Fragile X Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autism Spectrum Disorder",
        "Fra(X) Syndrome"
      ],
      "interventions": [
        {
          "name": "specimen collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Nova Mentis Life Science Corp",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "6 Months to 21 Years"
      },
      "enrollment_count": 300,
      "start_date": "2021-11-01",
      "completion_date": "2023-05",
      "has_results": false,
      "last_update_posted_date": "2021-10-13",
      "last_synced_at": "2026-07-23T06:11:37.216Z",
      "location_count": 1,
      "location_summary": "Fort Lauderdale, Florida",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04869930"
    },
    {
      "nct_id": "NCT02126995",
      "title": "A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "MG01CI extended-release tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alcobra Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "15 Years to 55 Years"
      },
      "enrollment_count": 62,
      "start_date": "2014-06",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2016-07-06",
      "last_synced_at": "2026-07-23T06:11:37.216Z",
      "location_count": 11,
      "location_summary": "Phoenix, Arizona • Sacramento, California • Aurora, Colorado + 8 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02126995"
    },
    {
      "nct_id": "NCT03569631",
      "title": "A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "FXS",
        "Fra(X) Syndrome"
      ],
      "interventions": [
        {
          "name": "BPN14770",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tetra Discovery Partners",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2018-07-09",
      "completion_date": "2020-07-31",
      "has_results": true,
      "last_update_posted_date": "2024-12-19",
      "last_synced_at": "2026-07-23T06:11:37.216Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03569631"
    },
    {
      "nct_id": "NCT03399461",
      "title": "Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wiskott-Aldrich Syndrome"
      ],
      "interventions": [
        {
          "name": "Patient Interview guide",
          "type": "OTHER"
        },
        {
          "name": "Caregiver interview guide",
          "type": "OTHER"
        },
        {
          "name": "Sociodemographic questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Pediatric quality of life (PedsQL) questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Clinical questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "30 Years",
        "sex": "MALE",
        "summary": "12 Years to 30 Years · Male only"
      },
      "enrollment_count": 19,
      "start_date": "2018-01-24",
      "completion_date": "2018-09-14",
      "has_results": false,
      "last_update_posted_date": "2019-03-14",
      "last_synced_at": "2026-07-23T06:11:37.216Z",
      "location_count": 1,
      "location_summary": "Collegeville, Pennsylvania",
      "locations": [
        {
          "city": "Collegeville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03399461"
    }
  ]
}