{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fragile+X+Syndrome+%28FXS%29",
    "query": {
      "condition": "Fragile X Syndrome (FXS)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 81,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Fragile+X+Syndrome+%28FXS%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T09:25:24.132Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00895752",
      "title": "Riluzole in Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Riluzole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2009-04",
      "completion_date": "2010-07",
      "has_results": true,
      "last_update_posted_date": "2017-04-18",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00895752"
    },
    {
      "nct_id": "NCT01911455",
      "title": "Study of Acamprosate in Fragile x Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "acamprosate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "23 Years",
        "sex": "ALL",
        "summary": "5 Years to 23 Years"
      },
      "enrollment_count": 46,
      "start_date": "2013-08-27",
      "completion_date": "2018-11-08",
      "has_results": false,
      "last_update_posted_date": "2021-02-03",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01911455"
    },
    {
      "nct_id": "NCT05367960",
      "title": "An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Zatolmilast/ BPN14770",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tetra Discovery Partners",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "9 Years to 45 Years · Male only"
      },
      "enrollment_count": 314,
      "start_date": "2022-11-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-03",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 17,
      "location_summary": "Irvine, California • Orange, California • Sacramento, California + 14 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05367960"
    },
    {
      "nct_id": "NCT05957549",
      "title": "Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG-Preschool Age",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Speech discrimination",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "4 Years",
        "sex": "ALL",
        "summary": "24 Months to 4 Years"
      },
      "enrollment_count": 90,
      "start_date": "2022-10-04",
      "completion_date": "2027-03-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-10",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05957549"
    },
    {
      "nct_id": "NCT03836300",
      "title": "Parent and Infant Inter(X)Action Intervention (PIXI)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "Angelman Syndrome",
        "Prader-Willi Syndrome",
        "Dup15Q Syndrome",
        "Duchenne Muscular Dystrophy",
        "Phelan-McDermid Syndrome",
        "Rett Syndrome",
        "Smith Magenis Syndrome",
        "Williams Syndrome",
        "Turner Syndrome",
        "Klinefelter Syndrome",
        "Chromosome 22q11.2 Deletion Syndrome",
        "Tuberous Sclerosis",
        "Down Syndrome"
      ],
      "interventions": [
        {
          "name": "Parent-Infant Inter(X)action Intervention (PIXI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "RTI International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "Up to 99 Years"
      },
      "enrollment_count": 120,
      "start_date": "2018-11-30",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Research Triangle Park, North Carolina",
      "locations": [
        {
          "city": "Research Triangle Park",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03836300"
    },
    {
      "nct_id": "NCT01254045",
      "title": "Double-blind Placebo Controlled Study of Oxytocin in Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "placebo",
          "type": "DRUG"
        },
        {
          "name": "oxytocin 24IU",
          "type": "DRUG"
        },
        {
          "name": "oxytocin 48IU",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "29 Years",
        "sex": "MALE",
        "summary": "13 Years to 29 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2007-02",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01254045"
    },
    {
      "nct_id": "NCT01894958",
      "title": "A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "NNZ-2566",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Neuren Pharmaceuticals Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "12 Years to 45 Years · Male only"
      },
      "enrollment_count": 72,
      "start_date": "2014-01",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2018-02-05",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 17,
      "location_summary": "Sacramento, California • Denver, Colorado • Washington D.C., District of Columbia + 14 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01894958"
    },
    {
      "nct_id": "NCT06413537",
      "title": "Study of SPG601 in Adult Men With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "SPG601",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Spinogenix",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2024-07-05",
      "completion_date": "2024-12-31",
      "has_results": true,
      "last_update_posted_date": "2026-05-26",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06413537"
    },
    {
      "nct_id": "NCT02747394",
      "title": "Cognitive Training for Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Working Memory Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 106,
      "start_date": "2013-01",
      "completion_date": "2018-10-18",
      "has_results": false,
      "last_update_posted_date": "2019-05-03",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02747394"
    },
    {
      "nct_id": "NCT01300923",
      "title": "Acamprosate in Youth With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome",
        "Autism Spectrum Disorders"
      ],
      "interventions": [
        {
          "name": "Acamprosate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 14,
      "start_date": "2010-08",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2019-07-30",
      "last_synced_at": "2026-06-10T09:25:24.132Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01300923"
    }
  ]
}