{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Frailty+Syndrome",
    "query": {
      "condition": "Frailty Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Frailty+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:18:23.644Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04132739",
      "title": "Piloting Diet and Exercise Interventions in Older Hispanics With Diabetes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Senior Syndrome",
        "Frailty"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Diet and exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Florida International University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2019-03-01",
      "completion_date": "2020-03-30",
      "has_results": false,
      "last_update_posted_date": "2021-01-06",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 4,
      "location_summary": "Miami, Florida • Sweetwater, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Sweetwater",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04132739"
    },
    {
      "nct_id": "NCT03413449",
      "title": "A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thoracic",
        "Thoracic Neoplasm",
        "Lung Cancer",
        "Esophageal Cancer",
        "Surgery--Complications",
        "Surgery",
        "Sarcopenia",
        "Malnutrition",
        "Frail Elderly Syndrome"
      ],
      "interventions": [
        {
          "name": "Frailty model",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 360,
      "start_date": "2018-01-08",
      "completion_date": "2024-11-08",
      "has_results": false,
      "last_update_posted_date": "2024-11-14",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03413449"
    },
    {
      "nct_id": "NCT01898611",
      "title": "Ghrelin Plus Strength Training in Frail Elderly Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Frailty Syndrome"
      ],
      "interventions": [
        {
          "name": "Ghrelin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "70 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2013-07-01",
      "completion_date": "2016-08-31",
      "has_results": true,
      "last_update_posted_date": "2019-12-11",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01898611"
    },
    {
      "nct_id": "NCT07563777",
      "title": "100-Year Human Aging Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aging",
        "Aging Well",
        "All-Cause Mortality",
        "Mortality",
        "Metabolic Syndrome",
        "Cardiovascular Diseases",
        "Cognitive Dysfunction",
        "Musculoskeletal Diseases",
        "Neoplasms",
        "Frailty",
        "Activities of Daily Living",
        "Health-Related Quality of Life",
        "Disability Physical",
        "Neuro-Degenerative Disease",
        "Dementia"
      ],
      "interventions": [
        {
          "name": "Comprehensive Multi-System Clinical Screening",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Longevity Metrics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2025-02-09",
      "completion_date": "2099-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07563777"
    },
    {
      "nct_id": "NCT04954690",
      "title": "Structured Program of Exercise for Recipients of Kidney Transplantation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Transplant; Complications",
        "Dialysis; Complications",
        "Physical Disability",
        "Frailty Syndrome"
      ],
      "interventions": [
        {
          "name": "Structured Program of exercise for Recipients of Kidney Transplantation (WC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Structured Program of exercise for Recipients of Kidney Transplantation (WC + CG)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2022-11-22",
      "completion_date": "2029-07",
      "has_results": false,
      "last_update_posted_date": "2023-10-16",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04954690"
    },
    {
      "nct_id": "NCT04804579",
      "title": "Boston ARCH 4F Intervention to Reduce Fall Risk in People With HIV and Alcohol Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infection",
        "Alcohol Consumption",
        "Falls, Accidental",
        "Falls"
      ],
      "interventions": [
        {
          "name": "Fall Prevention Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2021-10-20",
      "completion_date": "2022-08-01",
      "has_results": true,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04804579"
    },
    {
      "nct_id": "NCT05471011",
      "title": "COVID-19 Outcome Prediction Algorithm",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19",
        "Post Acute Sequelae of COVID-19",
        "Long COVID",
        "Organ Dysfunction Syndrome, Multiple",
        "Frailty Syndrome"
      ],
      "interventions": [
        {
          "name": "Blood and nasal swab sampling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2022-08-08",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Sylmar, California • Torrance, California + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sylmar",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05471011"
    },
    {
      "nct_id": "NCT04524247",
      "title": "Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracoabdominal Aortic Aneurysm",
        "Thoracoabdominal; Aortic, Aneurysm, Dissecting",
        "Pararenal Aneurysm",
        "Frailty Syndrome"
      ],
      "interventions": [
        {
          "name": "Physician Modified Endografts",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2021-02-23",
      "completion_date": "2032-07-02",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04524247"
    },
    {
      "nct_id": "NCT05858034",
      "title": "Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Customized activity plan",
          "type": "OTHER"
        },
        {
          "name": "Customized nutrition plan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2023-06-27",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05858034"
    },
    {
      "nct_id": "NCT02711709",
      "title": "Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Frailty Measurements",
          "type": "OTHER"
        },
        {
          "name": "Modified Minnesota Leisure Time Activities",
          "type": "OTHER"
        },
        {
          "name": "Computed tomography morphometrics",
          "type": "OTHER"
        },
        {
          "name": "Mobility Monitors",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2016-04",
      "completion_date": "2026-02-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-16",
      "last_synced_at": "2026-05-22T05:18:23.644Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02711709"
    }
  ]
}