{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=GREM1",
    "query": {
      "condition": "GREM1"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 2,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:54:50.529Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06342440",
      "title": "Early Detection of Advanced Adenomas and Colorectal Cancer",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Colorectal Cancer",
        "Colorectal Neoplasms",
        "Colorectal Polyp",
        "Colorectal Adenocarcinoma",
        "Colorectal Disorders",
        "Colorectal Dysplasia",
        "Colorectal Cancer Stage I",
        "Colorectal Cancer Stage II",
        "Colorectal Cancer Stage III",
        "Colorectal Cancer Stage IV",
        "Colorectal Neoplasms Malignant",
        "Colorectal Serrated Adenocarcinoma",
        "Colorectal Adenoma With Severe Dysplasia",
        "Colorectal Adenoma With Mild Dysplasia",
        "Colorectal Adenoma With Moderate Dysplasia",
        "Colorectal Adenoma and Carcinoma 1",
        "Colorectal Adenomatous Polyp",
        "Colorectal Adenocarcinoma Metastatic in the Liver"
      ],
      "interventions": [
        {
          "name": "DENEB",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "City of Hope Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2020-03-15",
      "completion_date": "2026-06-18",
      "has_results": false,
      "last_update_posted_date": "2025-06-17",
      "last_synced_at": "2026-05-22T03:54:50.529Z",
      "location_count": 2,
      "location_summary": "Monrovia, California • San Diego, California",
      "locations": [
        {
          "city": "Monrovia",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06342440"
    },
    {
      "nct_id": "NCT05420064",
      "title": "An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "BRCA1 Mutation",
        "POLD1 Gene Mutation",
        "CDKN2A Mutation",
        "BRCA2 Mutation",
        "POLE Gene Mutation",
        "APC Gene Mutation",
        "ATM Gene Mutation",
        "MLH1 Gene Mutation",
        "BARD1 Gene Mutation",
        "MSH2 Gene Mutation",
        "BRIP1 Gene Mutation",
        "MSH6 Gene Mutation",
        "CHEK2 Gene Mutation",
        "PMS2 Gene Mutation",
        "PALB2 Gene Mutation",
        "EPCAM Gene Mutation",
        "RAD51C Gene Mutation",
        "BMPR1A Gene Mutation",
        "RAD51D Gene Mutation",
        "SMAD4",
        "PTEN Gene Mutation",
        "GREM1"
      ],
      "interventions": [
        {
          "name": "Intervention Arm At-risk Relative/ARR Contacts",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MyGene Portal",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard of Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2022-12-01",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-05-22T03:54:50.529Z",
      "location_count": 8,
      "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        },
        {
          "city": "Middletown",
          "state": "New Jersey"
        },
        {
          "city": "Montvale",
          "state": "New Jersey"
        },
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "Harrison",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05420064"
    }
  ]
}