{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gastro-esophageal+Reflux",
    "query": {
      "condition": "Gastro-esophageal Reflux"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 96,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gastro-esophageal+Reflux&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T10:13:23.977Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05696184",
      "title": "Mechanisms Preventing Pharyngeal Reflux",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "GERD"
      ],
      "interventions": [
        {
          "name": "Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Slow and rapid intra-esophageal infusion",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 300,
      "start_date": "2013-11-01",
      "completion_date": "2026-10-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05696184"
    },
    {
      "nct_id": "NCT02227927",
      "title": "Treatment Use of Domperidone for Gastroparesis",
      "overall_status": "NO_LONGER_AVAILABLE",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Gastroesophageal Reflux Disease",
        "GERD",
        "Gastroparesis"
      ],
      "interventions": [
        {
          "name": "Domperidone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Scott Gabbard, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2025-06-29",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 2,
      "location_summary": "Weston, Florida • Cleveland, Ohio",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02227927"
    },
    {
      "nct_id": "NCT00260572",
      "title": "Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "Questionnaires to evaluate QOL",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaires to evaluate heartburn and quality of life",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaire to evaluate satisfaction with treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaire to evaluate presence or absence of pain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2500,
      "start_date": "1999-04",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00260572"
    },
    {
      "nct_id": "NCT00206180",
      "title": "NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Erosive Esophagitis",
        "Reflux Esophagitis",
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "esomeprazole magnesium (oral medication)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AstraZeneca",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 120,
      "start_date": "2004-06",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2009-03-26",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 39,
      "location_summary": "Alabaster, Alabama • Anaheim, California • Dinuba, California + 36 more",
      "locations": [
        {
          "city": "Alabaster",
          "state": "Alabama"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Dinuba",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00206180"
    },
    {
      "nct_id": "NCT00582972",
      "title": "Does Omeprazole Decrease Intestinal Calcium Absorption?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Osteoporosis",
        "Achlorhydria",
        "GERD",
        "Hip Fracture"
      ],
      "interventions": [
        {
          "name": "Omeprazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 23,
      "start_date": "2008-01",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2013-02-15",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00582972"
    },
    {
      "nct_id": "NCT00222079",
      "title": "Evaluation of Esomeprazole in Treating Gastro-esophageal Reflux Disease (GERD) in Head and Neck Cancer Patients Exposed to Radiation Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastro-esophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Esomeprazole (Nexium)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Douglas Trask",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2004-11",
      "completion_date": "2008-02",
      "has_results": false,
      "last_update_posted_date": "2017-12-14",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00222079"
    },
    {
      "nct_id": "NCT04901429",
      "title": "Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric Bypass",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "GERD"
      ],
      "interventions": [
        {
          "name": "Truncal vagotomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2021-07-01",
      "completion_date": "2028-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-25",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901429"
    },
    {
      "nct_id": "NCT03143608",
      "title": "GERD Treatment With Transoral Incisionless Fundoplication (TIF) Following Hiatal Hernia Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gastro Esophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Esophyx",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Peter G Mavrelis",
      "sponsor_class": "INDIV",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 99,
      "start_date": "2014-05-01",
      "completion_date": "2016-12-31",
      "has_results": false,
      "last_update_posted_date": "2017-05-08",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 2,
      "location_summary": "Merrillville, Indiana • Appleton, Wisconsin",
      "locations": [
        {
          "city": "Merrillville",
          "state": "Indiana"
        },
        {
          "city": "Appleton",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03143608"
    },
    {
      "nct_id": "NCT03939819",
      "title": "Endoscopic vs. Suction Device Calibration in Sleeve Gastrectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastrectomy",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "ViSiGi® 3D suction calibration device",
          "type": "DEVICE"
        },
        {
          "name": "Esophagogastroduodenoscopy (EGD) calibration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 106,
      "start_date": "2019-07-30",
      "completion_date": "2022-02-02",
      "has_results": true,
      "last_update_posted_date": "2024-05-21",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03939819"
    },
    {
      "nct_id": "NCT00847210",
      "title": "Pharmacokinetic and Safety of Dexlansoprazole in Adolescents With Gastroesophageal Reflux Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Dexlansoprazole MR",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 36,
      "start_date": "2009-05",
      "completion_date": "2009-09",
      "has_results": true,
      "last_update_posted_date": "2012-02-02",
      "last_synced_at": "2026-07-22T10:13:23.977Z",
      "location_count": 3,
      "location_summary": "Anaheim, California • Cypress, California • Overland Park, Kansas",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Cypress",
          "state": "California"
        },
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00847210"
    }
  ]
}