{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gastro-intestinal+Tolerance",
    "query": {
      "condition": "Gastro-intestinal Tolerance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 55,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gastro-intestinal+Tolerance&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T15:14:52.843Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00889473",
      "title": "Study of the Efficacy of Larazotide Acetate to Treat Celiac Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Celiac Disease"
      ],
      "interventions": [
        {
          "name": "Larazotide acetate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Gluten 900 mg",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "9 Meters Biopharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "72 Years",
        "sex": "ALL",
        "summary": "18 Years to 72 Years"
      },
      "enrollment_count": 42,
      "start_date": "2009-04",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2017-09-20",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 14,
      "location_summary": "Orange, California • Topeka, Kansas • Lexington, Kentucky + 11 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Topeka",
          "state": "Kansas"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Hagerstown",
          "state": "Maryland"
        },
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00889473"
    },
    {
      "nct_id": "NCT05668468",
      "title": "A Bifido Bacteria to Improve Lactose Digestion and Tolerance",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lactose Intolerance"
      ],
      "interventions": [
        {
          "name": "Bifidobacterium adolescentis IVS-1 capsule",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo cellulose capsule",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 35,
      "start_date": "2022-05-01",
      "completion_date": "2024-05-01",
      "has_results": false,
      "last_update_posted_date": "2022-12-29",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05668468"
    },
    {
      "nct_id": "NCT05794100",
      "title": "Evaluating the Impact of Different Sugar Replacer Combinations on Gastrointestinal Tolerance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tolerance",
        "Healthy Population"
      ],
      "interventions": [
        {
          "name": "Acute intake of one of the products (active comparator 1 to 9) or Placebo comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mondelēz International, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 60,
      "start_date": "2021-10-11",
      "completion_date": "2022-07-30",
      "has_results": false,
      "last_update_posted_date": "2023-04-03",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "Addison, Illinois",
      "locations": [
        {
          "city": "Addison",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05794100"
    },
    {
      "nct_id": "NCT00194922",
      "title": "Study to Determine the Effectiveness of the Probiotic E. Coli Strain M17 in Treating Irritable Bowel Syndrome (IBS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Irritable Bowel Syndrome (IBS)"
      ],
      "interventions": [
        {
          "name": "E. Coli Strain M17 Probiotic",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 35,
      "start_date": "2004-08",
      "completion_date": "2006-11",
      "has_results": false,
      "last_update_posted_date": "2008-04-04",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00194922"
    },
    {
      "nct_id": "NCT00922727",
      "title": "Safety of Lactobacillus Reuteri (L. Reuteri) in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Colic",
        "Gastrointestinal Tract Infections"
      ],
      "interventions": [
        {
          "name": "L. reuteri",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sunflower Oil",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 40,
      "start_date": "2009-10",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2018-01-25",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00922727"
    },
    {
      "nct_id": "NCT02565472",
      "title": "Effects of Juice on Gastrointestinal Tolerance and Breath Hydrogen Response in Human Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Food Selection"
      ],
      "interventions": [
        {
          "name": "White grape juice",
          "type": "OTHER"
        },
        {
          "name": "Apple juice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2015-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-02-24",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02565472"
    },
    {
      "nct_id": "NCT01965769",
      "title": "Effects Of Not Measuring Gastric Residual Content On Feeding Tolerance In Premature Infants iNFANTS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Infant"
      ],
      "interventions": [
        {
          "name": "No gastric residual evaluation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Days",
        "sex": "ALL",
        "summary": "Up to 3 Days"
      },
      "enrollment_count": 61,
      "start_date": "2011-03",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2013-10-18",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01965769"
    },
    {
      "nct_id": "NCT03967132",
      "title": "Growth and Tolerance of Infants Fed Milk-Based Infant Formula",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastro-Intestinal Tolerance"
      ],
      "interventions": [
        {
          "name": "Control Infant Formula",
          "type": "OTHER"
        },
        {
          "name": "Experimental Infant Formula",
          "type": "OTHER"
        },
        {
          "name": "Reference Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abbott Nutrition",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "14 Days",
        "sex": "ALL",
        "summary": "Up to 14 Days"
      },
      "enrollment_count": 189,
      "start_date": "2019-06-08",
      "completion_date": "2020-05-29",
      "has_results": false,
      "last_update_posted_date": "2020-09-22",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 19,
      "location_summary": "Tucson, Arizona • Sacramento, California • Norwich, Connecticut + 16 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Norwich",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03967132"
    },
    {
      "nct_id": "NCT05432648",
      "title": "Fiber Food Introduction in Pediatric Short Bowel Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Short Gut Syndrome"
      ],
      "interventions": [
        {
          "name": "Green bean puree",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "4 Months to 18 Years"
      },
      "enrollment_count": 60,
      "start_date": "2022-05-08",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2025-08-17",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05432648"
    },
    {
      "nct_id": "NCT02456805",
      "title": "Alternate Formula Feedings in Formula Intolerant Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastrointestinal Tolerance"
      ],
      "interventions": [
        {
          "name": "Infant Formula 1",
          "type": "OTHER"
        },
        {
          "name": "Infant Formula 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abbott Nutrition",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Weeks",
        "maximum_age": "9 Weeks",
        "sex": "ALL",
        "summary": "2 Weeks to 9 Weeks"
      },
      "enrollment_count": 113,
      "start_date": "1996-08",
      "completion_date": "1997-06",
      "has_results": false,
      "last_update_posted_date": "2015-05-29",
      "last_synced_at": "2026-06-26T15:14:52.843Z",
      "location_count": 7,
      "location_summary": "Little Rock, Alaska • Aurora, Colorado • Stone Mountain, Georgia + 4 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Alaska"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Stone Mountain",
          "state": "Georgia"
        },
        {
          "city": "Dubuque",
          "state": "Iowa"
        },
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02456805"
    }
  ]
}