{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=GastroEsophageal+Reflux+Disease",
    "query": {
      "condition": "GastroEsophageal Reflux Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 447,
    "total_pages": 45,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=GastroEsophageal+Reflux+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-13T13:21:51.100Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00855361",
      "title": "A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in New Born Infants With Gastroesophageal Reflux Disease (GERD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Rabeprazole sodium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Janssen Research & Development, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "44 Weeks",
        "sex": "ALL",
        "summary": "Up to 44 Weeks"
      },
      "enrollment_count": 69,
      "start_date": "2009-07",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2013-04-29",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 10,
      "location_summary": "Orange, California • Washington D.C., District of Columbia • Augusta, Georgia + 7 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Maywood",
          "state": "Illinois"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00855361"
    },
    {
      "nct_id": "NCT00295685",
      "title": "Nexium 40mg Once Daily vs Prevacid 30mg Twice a Day for Control of Severe GERD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "GERD"
      ],
      "interventions": [
        {
          "name": "Antacids",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Digestive & Liver Disease Specialists",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2005-10",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2009-02-25",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00295685"
    },
    {
      "nct_id": "NCT01053286",
      "title": "Stimulation of Sensation and Improvement in Swallowing Using Oral Capsaicin",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dysphagia",
        "Gastroesophageal Reflux"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2009-10",
      "completion_date": "2012-07",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01053286"
    },
    {
      "nct_id": "NCT04301986",
      "title": "Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Barrett Esophagus",
        "GERD"
      ],
      "interventions": [
        {
          "name": "Cytosponge",
          "type": "DEVICE"
        },
        {
          "name": "Transnasal Endoscopy (TNE)",
          "type": "DEVICE"
        },
        {
          "name": "Esophagogastroduodenoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2020-08-11",
      "completion_date": "2022-05-10",
      "has_results": true,
      "last_update_posted_date": "2023-05-08",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04301986"
    },
    {
      "nct_id": "NCT03366012",
      "title": "Rapid Assessment of Esophageal Adenocarcinoma Risk Test",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Barrett Esophagus",
        "Esophageal Adenocarcinoma"
      ],
      "interventions": [
        {
          "name": "Cytosponge",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 51,
      "start_date": "2018-08-01",
      "completion_date": "2023-05-19",
      "has_results": true,
      "last_update_posted_date": "2024-11-08",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03366012"
    },
    {
      "nct_id": "NCT02930824",
      "title": "Genotype-supported Versus Conventional Proton Pump Inhibitor Dosing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "CYP2C19 genotyping",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "5 Years to 100 Years"
      },
      "enrollment_count": 185,
      "start_date": "2016-12",
      "completion_date": "2019-07-17",
      "has_results": true,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida • Orlando, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02930824"
    },
    {
      "nct_id": "NCT01921686",
      "title": "Morphological Markers of Gastroesophageal Reflux Disease (GERD)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eosinophilic Esophagitis",
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "Sample collection and Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 54,
      "start_date": "2013-03",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01921686"
    },
    {
      "nct_id": "NCT01288612",
      "title": "Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts Esophagus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Barrett's Esophagus"
      ],
      "interventions": [
        {
          "name": "Sedated Endoscopy",
          "type": "DEVICE"
        },
        {
          "name": "Transnasal Endoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "50 Years to 95 Years"
      },
      "enrollment_count": 459,
      "start_date": "2011-02",
      "completion_date": "2013-10",
      "has_results": true,
      "last_update_posted_date": "2015-01-07",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01288612"
    },
    {
      "nct_id": "NCT00586963",
      "title": "Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Erosive Esophagitis",
        "Reflux Esophagitis",
        "GERD"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2008-01",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2010-08-23",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00586963"
    },
    {
      "nct_id": "NCT01696734",
      "title": "Domperidone in Treating Patients With Gastrointestinal Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Digestive System Disorder",
        "Dyspepsia",
        "Esophagitis",
        "Gastroesophageal Reflux Disease",
        "Gastroparesis",
        "Heartburn",
        "Nausea and Vomiting"
      ],
      "interventions": [
        {
          "name": "Domperidone",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2012-10-23",
      "completion_date": "2027-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-06-13T13:21:51.100Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01696734"
    }
  ]
}