{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Gender+Affirmation+Surgery",
    "query": {
      "condition": "Gender Affirmation Surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:10:55.304Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06436560",
      "title": "Support for Transgender and Non-Binary Individuals Seeking Vaginoplasty Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gender Affirmation Surgery",
        "Perioperative Care",
        "Transgender Health"
      ],
      "interventions": [
        {
          "name": "STRIVE Peer Support Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 290,
      "start_date": "2024-12-10",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 9,
      "location_summary": "San Francisco, California • Chicago, Illinois • Detroit, Michigan + 6 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06436560"
    },
    {
      "nct_id": "NCT05372770",
      "title": "Flourish Vaginal Care System to Establish Neovaginal Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neovaginal Microbiome"
      ],
      "interventions": [
        {
          "name": "Flourish Vaginal Care system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vaginal Biome Science",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2022-01-24",
      "completion_date": "2024-12-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-01",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "New Hope, Pennsylvania",
      "locations": [
        {
          "city": "New Hope",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05372770"
    },
    {
      "nct_id": "NCT06443164",
      "title": "Efficacy of a Chronic Pain Treatment Prior to Gender-affirming Surgery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Catastrophizing",
        "Pain, Chronic",
        "Gender Identity"
      ],
      "interventions": [
        {
          "name": "Empowered Relief",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 78,
      "start_date": "2024-05-15",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06443164"
    },
    {
      "nct_id": "NCT06073808",
      "title": "The Role of Amnion Membrane Allografts in Nipple Preservation",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mastectomy",
        "Gender Affirmation Surgery",
        "Nipple Sparing Mastectomy",
        "Prophylactic Mastectomy",
        "Benign Breast Condition"
      ],
      "interventions": [
        {
          "name": "AmnioFix dehydrated Human Amnion/Chorion Membrane Allograft",
          "type": "DEVICE"
        },
        {
          "name": "Control Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "15 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-06-01",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06073808"
    },
    {
      "nct_id": "NCT04979338",
      "title": "Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gender Dysphoria"
      ],
      "interventions": [
        {
          "name": "Ultrasound guided Continuous Infraclavicular Brachial Plexus Block",
          "type": "OTHER"
        },
        {
          "name": "Ultrasound guided Continuous Femoral Nerve Block",
          "type": "OTHER"
        },
        {
          "name": "Ultrasound guided Pudendal Nerve Block",
          "type": "OTHER"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bilateral ultrasound guided Transversus Abdominis Plane Block",
          "type": "OTHER"
        },
        {
          "name": "Bilateral spermatic cord block",
          "type": "OTHER"
        },
        {
          "name": "Pecs I & II Block",
          "type": "OTHER"
        },
        {
          "name": "Local anesthetic",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 640,
      "start_date": "2021-11-11",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04979338"
    },
    {
      "nct_id": "NCT04474366",
      "title": "The Effect of Pectoral Blocks on Perioperative Pain in Gender Affirmation Top Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gender Dysphoria",
        "Opioid Use",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Ropivacaine 0.2% Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Saline (0.9%)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2020-06-16",
      "completion_date": "2022-04-30",
      "has_results": true,
      "last_update_posted_date": "2023-07-03",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04474366"
    },
    {
      "nct_id": "NCT03293771",
      "title": "Transgender Post-reassignment Urogynecologic Measures and Perceptions",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gender Identity Disorder of Adult",
        "Voiding Disorders",
        "Sexual Dysfunction"
      ],
      "interventions": [
        {
          "name": "Focus group interviews",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire packet",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 200,
      "start_date": "2017-12-27",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-04-23",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03293771"
    },
    {
      "nct_id": "NCT07324967",
      "title": "A Standardized Counseling Approach to Preoperative Education in Transmasculine Individuals Receiving Gender-affirming Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hysterectomy",
        "Gender Affirming Surgery"
      ],
      "interventions": [
        {
          "name": "Educational Handout",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 250,
      "start_date": "2026-03-12",
      "completion_date": "2028-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-03",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07324967"
    },
    {
      "nct_id": "NCT06428669",
      "title": "Effect of Nitropaste in Chest Masculinizing Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gender Dysphoria"
      ],
      "interventions": [
        {
          "name": "Nitro-Bid 2 % Topical Ointment",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 256,
      "start_date": "2022-08-15",
      "completion_date": "2025-11",
      "has_results": false,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06428669"
    },
    {
      "nct_id": "NCT06565663",
      "title": "MaPGAS Decision Making",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gender Dysphoria",
        "Gender Dysphoria, Adult",
        "Gender Incongruence",
        "Transgenderism",
        "Transsexualism",
        "Transgender Persons",
        "Phalloplasty"
      ],
      "interventions": [
        {
          "name": "MaPGAS Decision Aid",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 140,
      "start_date": "2024-10-23",
      "completion_date": "2028-03-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-05-22T08:10:55.304Z",
      "location_count": 2,
      "location_summary": "Hanover, New Hampshire • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Hanover",
          "state": "New Hampshire"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06565663"
    }
  ]
}