{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Genetic+Variation",
    "query": {
      "condition": "Genetic Variation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 207,
    "total_pages": 21,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Genetic+Variation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T09:00:56.937Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01971957",
      "title": "Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sjogren-Larsson Syndrome (SLS)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2013-04-01",
      "completion_date": "2023-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-08",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 2,
      "location_summary": "Omaha, Nebraska • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01971957"
    },
    {
      "nct_id": "NCT00710177",
      "title": "PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Persistent Pulmonary Hypertension of the Newborn"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "Up to 12 Months"
      },
      "enrollment_count": 200,
      "start_date": "2006-01",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00710177"
    },
    {
      "nct_id": "NCT02408445",
      "title": "Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Klinefelter Syndrome"
      ],
      "interventions": [
        {
          "name": "testosterone cypionate 200mg/ml",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "42 Days",
        "maximum_age": "108 Days",
        "sex": "MALE",
        "summary": "42 Days to 108 Days · Male only"
      },
      "enrollment_count": 20,
      "start_date": "2015-05-08",
      "completion_date": "2020-01-01",
      "has_results": true,
      "last_update_posted_date": "2020-04-15",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02408445"
    },
    {
      "nct_id": "NCT05656261",
      "title": "APOL1 Genetic Testing in African Americans",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Genetic Predisposition",
        "Chronic Kidney Diseases",
        "Nephropathy",
        "APOL1 Associated Kidney Disease",
        "Disparities"
      ],
      "interventions": [
        {
          "name": "Assessment of the frequency of APOL-1 renal risk variant in the black population, and evaluating their attitudes about genetic testing and APOL1 genotype via self-administered surveys",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 600,
      "start_date": "2019-01-24",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-20",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05656261"
    },
    {
      "nct_id": "NCT00040469",
      "title": "Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Sickle Cell Anemia",
        "Hemoglobinopathy",
        "Thalassemia"
      ],
      "interventions": [
        {
          "name": "Campath -1H",
          "type": "DRUG"
        },
        {
          "name": "Dilantin",
          "type": "DRUG"
        },
        {
          "name": "Busulfan",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "1 Day to 64 Years"
      },
      "enrollment_count": 15,
      "start_date": "2000-08",
      "completion_date": "2003-11-21",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00040469"
    },
    {
      "nct_id": "NCT01650948",
      "title": "Genetic Load and Phenotype in Aggressive AMD",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Age-related Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "RetnaGene AMD LDT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sequenom, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2012-07",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-01-20",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Lexington, Kentucky • Nashville, Tennessee",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01650948"
    },
    {
      "nct_id": "NCT06334315",
      "title": "Oral Contraceptive Pill (OCP) Pharmacogenomics",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Contraception",
        "Pharmacogenomic Drug Interaction"
      ],
      "interventions": [
        {
          "name": "Desogestrel / Ethinyl Estradiol Pill",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 700,
      "start_date": "2024-10-29",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • New Haven, Connecticut",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06334315"
    },
    {
      "nct_id": "NCT02487888",
      "title": "A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Chronic Pain",
        "Mental Disorders",
        "Cardiovascular Diseases",
        "Diabetes Mellitus, Type 2",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Unblinded to Genetic Testing Results",
          "type": "OTHER"
        },
        {
          "name": "Blinded to Genetic Testing Results",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Proove Bioscience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100000,
      "start_date": "2014-09",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2016-03-30",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 31,
      "location_summary": "Beverly Hills, California • Fresno, California • La Jolla, California + 23 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02487888"
    },
    {
      "nct_id": "NCT02428660",
      "title": "Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cytochrome P450 CYP2D6 Enzyme Deficiency",
        "Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant",
        "Ultrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant",
        "Extensive Metabolizer Due to Cytochrome P450 CYP2D6 Variant",
        "Cytochrome P450 CYP2C9 Enzyme Deficiency",
        "Cytochrome P450 CYP2C19 Enzyme Deficiency",
        "Drug Metabolism, Poor, CYP2D6-RELATED",
        "Drug Metabolism, Poor, CYP2C19-RELATED",
        "CYP2D6 Polymorphism"
      ],
      "interventions": [
        {
          "name": "Pharmacogenetic testing",
          "type": "GENETIC"
        },
        {
          "name": "Software-based drug & gene interaction risk analysis",
          "type": "OTHER"
        },
        {
          "name": "MTM",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "GENETIC",
        "OTHER"
      ],
      "sponsor": "Genelex Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 341,
      "start_date": "2015-02",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2017-02-23",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02428660"
    },
    {
      "nct_id": "NCT05419245",
      "title": "Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Freeman-Burian Syndrome",
        "Freeman-Sheldon Syndrome",
        "Whistling Face Syndrome",
        "Sheldon-Hall Syndrome",
        "Freeman-Sheldon Syndrome Variant",
        "Arthrogryposis Distal Type 1",
        "Arthrogryposis Distal Type 3",
        "Gordon Syndrome"
      ],
      "interventions": [
        {
          "name": "Guided Health History for Freeman-Burian Syndrome Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Freeman-Burian syndrome Semi-Structured Quality of Life Interview",
          "type": "OTHER"
        },
        {
          "name": "Medical Records Review",
          "type": "OTHER"
        },
        {
          "name": "PTSD Checklist for DSM-5",
          "type": "OTHER"
        },
        {
          "name": "Modified Flanagan Quality of Life Scale",
          "type": "OTHER"
        },
        {
          "name": "Center for Epidemiologic Studies Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Review of Systems",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Craniofacial - Appearance of the Face",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Craniofacial - Appearance Distress",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Craniofacial - Facial Function",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dufresne, Craig, MD, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-01",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-06-26T09:00:56.937Z",
      "location_count": 1,
      "location_summary": "Fairfax, Virginia",
      "locations": [
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05419245"
    }
  ]
}